Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Modern Hospital》 2004-11
Add to Favorite Get Latest Update

Comparison of The Effects of Stragalus membranaceus and Anisodamine on Lung Isch emia /Reperfusion Injury During Hemorrhage Shock in Rabbits

Lin ShiQing, Hei ZiQing, Mo LiQiu, et al. The First Affiliated Hospital of ZhongShan University. GuangZhou 510080  
Objective To compare the effects of stragalus membranaceus and anisodamine on lung ischemia╱reperfusion injury during hemorrhage shock i n rabbits. Methods 24 rabbits were randomly divided into thre e Groups: Group H (n=8), used Astragalus membranaceus (10 g/kg); Group S ( n=8), used Anisodamine (2.5 mg/kg); Group C (n=8), used saline as thera peutic drugs. After hemorrhage shock 60 minutes and recovering therapy 60 minnu tes, wet weight/dry weight ratio (W/D) and injury scores of lung, SOD and MDA of lung tissue were detected. Results Histopathologic examinatio n results show that lung injury in Group H or Group S was mild or moderate, but severe or maximum in Group C. The values of W/D and lung injury scores in Group H and Group S were lower than that in Group C(P0.01), but there were no significantly difference between Group H and Group C (P0.05). Compared to other two Groups, SOD was the lowest and MDA highest in Group C (P0.01 or P0.05), SOD was highest and MDA lowest in Group H (P0.01 or P0.05). Conclusions Stragalus membranaceus can more signi f icantly reduce oxygen-derived free radicals in pulmonary tissue than anisodamine , but both have similar effect on avoiding the lung damage during hemorrhage sho ck in rabbits.
【CateGory Index】: R605.971
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 4 Hits
1 /LI Quanmin;YAO Zhen;GAOShangzhi; et alChinese Critical Care Medicine,;Therapeutic effects of combined admiinistration of halfdose of dexamethasone and anisodamine on severe hem-orrhagic shook[J];CHINESE CRITICAL CARE MEDICINE;1995-06
2 DENG You-hua, GUO Zheng-heng, CHEN Hong-ming, QIN Zhong-wei, QIN Zhi-jian, HE Yin-lei (Department of Cardiothoracic Surgery, Affiliated Hospital of Youjiang Medical College for Nationalities, Bose, Guangxi 533000, P.R.China);The combination of Anisodamine with exogenous pulmonary surfactant in protecting the ischemic-reperfusion lung injury[J];Journal of Youjiang Medical College For Nationalities;2002-02
3 WU Hao 1, CHAO Fu 2, YANG Hongsheng 2, AI Ziqiang 3. 1. Department of Thoracic Surgery, the First Hospital of Hangzhou City, Hangzhou 310006, Zhejiang, China; 2. Department of Thoracic Surgery, the First Affiliated Hospital, Kunming Medical College, Kunming 650032, Yunnan, China; 3. Traffic Hospital of Yunnan Province, Kunming 650106, Yunnan, China;Experimental study on protective effect of anisodamine on lung ischemia/reperfusion injury in rabbits[J];Chinese Journal of Integrated Traditional and Western Medicine in Intentire Critical Care;2003-05
4 LIN Shi-qing, HEI Zi-qing , CHEN Bing-xue , et al. Department of Anesthesiology, First Affiliated Hospital, Zhongshan Unixesity, Guangzhou 510080, China;Effect of astragalus membranaceus on the ultrastructure of small intestinal epithelial cells in rabbits with hemorrhagic shock[J];Chinese Journal of Anesthesiology;2003-06
【Co-citations】
Chinese Journal Full-text Database 9 Hits
1 XIE Hui-chen,LIU Fen,YANG Qiang(Medical College of Hubei Institute for Nationalities,Enshi 445000,China);Regulatory Effects of Panax Ginseng and Astragalus Membranaceus Injection on Glucocorticoid Receptor Concentration of Intestinal Mucosa after Hemorrhage Shock-Reperfusion in Rats[J];Journal of Hubei University for Nationalities(Medical Edition);2008-04
2 Yang Xiaolong,Yuan Shiying.Department of Anesthesiology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022;Effects of penequinine hydrochloride on septic lung injury in rats[J];Central China Medical Journal;2007-02
3 Daixing Zhou, Chengye Zhan, Puzhen Deng Department of Emergency, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China;Effects of anisodamine on altered [Ca~(2+)]i and cerebral cortex ultrastructure following acute cerebral ischemia/reperfusion injury in rabbits[J];中国神经再生研究(英文版);2008-10
4 HEI Zi-qing 1, ZHANG Jin-jun 2, LIN Shi-qing 2, LIU Ke-xuan 2, CHEN Bing-xue 2 (1. Department of Anesthesiology, The Third Affiliated Hospital of Zhong Shan University, Guangzhou 510630, China; 2. Department of Anesthesiology, The First Affiliated Hospital of Zhong Shan University, Guangzhou 510080, China);Effects of Astragalus membranaceus injection on nitric oxide and endothelin concentration of intestinal mucosa after hemorrhage shock-reperfusion in rats[J];China Journal of Chinese Materia Medica;2004-05
5 WANG Zhiwei,WU Yinai,LIU Xiantang,JIANG Banghao,HU Shixiong,LUO Zhendong,JIN Haosheng.Department of General Surgery,the 157th Hospital of PLA,Guangzhou 510510,Guangdong,China;Protective effect of dexamethasone on celiac seawater immersion wound in rats[J];Chinese Critical Care Medicine;2002-07
6 XIE Lixin~, LIU Youning, ZHAO Xiaowei, CHEN Liangan, HUANG Lijie, HAO Fengying, CAO Lu.~ Department of Respiratory Medicine, General Hospital of PLA, Beijing 100853, China;Effects of lung protective ventilation in prone or supine position on inhibiting adrenomedulin release in acute respiratory distress syndrome caused by pulmonary and extrapulmonary insults in dog[J];Chinese Critical Care Medicine;2005-08
7 GENG Qing, WU Da, XIE Yuancai, ZHANG Bengu, WU Hao, YIN Weihua. Department of Thoracic Surgery, Shenzhen Hospital, Peking University, Shenzhen 518036, Guangdong, China;Effects of ginsenoside Rb1 on apoptosis and Bcl-2, Bax gene expression in rabbits with lung ischemia/reperfusion injury[J];Chinese Journal of Integrated Traditional and Western Medicine in Intentire Critical Care;2005-03
8 LIN Shi-qing, HEI Zi-qing , CHEN Bing-xue , et al. Department of Anesthesiology, First Affiliated Hospital, Zhongshan Unixesity, Guangzhou 510080, China;Effect of astragalus membranaceus on the ultrastructure of small intestinal epithelial cells in rabbits with hemorrhagic shock[J];Chinese Journal of Anesthesiology;2003-06
9 CAO Huan-jun ZHANG Cheng-ming Sun Yong-hong,et al.( Department of Anesthesiology,Weifang Medical College,Weifang 261042,China);Protect Effect of Radix Injection Fluid on Stress Ulcer in Rats[J];Journal of Clinical Emergency Call;2008-03
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LIAO Yi-hua\+1, DENG Yun-mei\+1, DENG Jing-xiu\+1, CHENG Wei\+2, MEI Yong-hong\+1 (1.No.457 Hospital of PLA,Wuhan 430012,Hubei,China; 2\^The Affiliated Hospital of Hubei College of TCM,Wuhan 430061,Hubei,China);Protective Effects of Astragalus Membranaceus Injection on Myocardial Ischemia-Reperfusion in Rabbits[J];Journal of Liaoning College of Traditional Chinese Medicine;2002-03
2 WANG Jianxin,MEI Guanglin,HU Weidong (Department of General Surgery, Affiliated Hospital of Nantong University,Nantong226001);Protective effect of astragalus membranaceus on hepatic ischemia-reperfusion injury[J];Journal of Nantong Medical;2005-03
3 Yue Maoxing;Li Chenglin; Li Ximgyuan, et al.( Department of General Surgery, General Hospital, The commission ofHead Equipment Ministry of the People's Republic of China, Beijing 100101);The effect of anisodaminum and dexamethasone to the TNF and LPO in models of rabbit[J];JOURNAL OF EMERGENOY MEDICINE;1999-01
4 FENG Jinping, YAO Zhi, ZHAO Bingrang Department of 'Cardiology, Tianjin Chest Hospital 300051;Changes of Cytokines in Myocardial Apoptosis during Ischemia/Reperfusion and Effects of Huangqi on Them[J];Tianjing Medical Journal;2001-07
5 YU Qin-chao, ZHU Tong-yu, ZHANG Yong-kang, ZHANG Li, GUAN Jian-ming(Department of Urology,Zhongshan Hospital,Fudan University,Shanghai 200032,China);Effect of Astrgaloside Ⅳ on Long-term MCP-1 Expression in Renal Ischemia-reperfusion Injury in the Rat[J];Journal of Shanghai Medica(University);2004-06
6 Affiliated Hospital,Medical College,Yan'an University (Yan'an 716000) Li Hui,Jiang Fengyuan,Guo Long;Protective effect of Radix Astragali(Astragalus root) and vitamin E on ischemic reinfusion injury of limbs in rabbits[J];Shaanxi Medical Journal;2004-03
7 WU Hao,CHAO Fu,YANG Hong-sheng,et al.(Department of Thoracic Surgery, the First Affiliated Hospital of Kunming Medical College,Kunming 650032,China);Experimental study on protective effect of anisodamine on lung ischemia-reperfusion injury in rabbits[J];Medicine and Pharmacy of Yunnan;2005-01
8 YUAN Chun-hui, LIU Yong-feng, CHENG Ying, et al Department of Organ Transplantation, The First Affiliated Hospital of China Medical University, Shenyang (110001);Experimental Study on Effect of Astragalus Extractum on Canine Isolated Kidney during Hypothermia Perfusion and Preservation[J];Chinese Journal of Integrated Traditional and Western Medicine;2003-04
9 SHI Zeng-li, LEI Ning-yu, LIU Feng, et al. Department of Pathophysiology, Binzhou Medical College, Shandong Binzhou, 256603, China;Effects of Anisodamine Pretreatment on Cytokins in Serum and Pulmonary in Rats with ARDS[J];Journal of Chinese Microcirculation;2003-05
10 Qu Youzhi,Zhao Yanling,Zhao Zhenwei,et al;The Effects of Astragus on the Content of IL-1βand the Activity of MPO in Rats after Cerebral Ischemia-Reperfusion[J];Journal of Emergency in Traditional Chinese Medicine;2006-02
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 WANG Xin, HAN Jiyuan. Emergency Department,Wuhan Union Hospital Affiliated to the Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022,China;Advances in treatment of acute lung injury in paraquat poisoning[J];International Journal of Emergency and Critical Care Medicine;2007-03
2 FAN Yi-feng LI De-ruing XU Xin (Affiliated Hospital of Nantong University,Nantong 226001,China);Content determination of Raceanisodamine Mixture by HPLC[J];China Medical Herald;2008-05
【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 Xing Quansheng, Zhang Shantong, Chen Zhanggen, et al. Department of Cardiothoracic Surgery,Children's Hospital, Shanghai Medical University 200032;The effects of cardiopulmonary by pass on pulmonary surfactant activity[J];CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES;1997-04
2 Wang Deqing, Wang Chengbin, Tian Yaping, et al General Hospital of PLA, Beijing (100853);Effect of Total Flavonoids of Astragalus on Nitroxide in Ischemia Reperfusion Injury[J];CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE;1999-04
3 /LI Quanmin;YAO Zhen;GAOShangzhi; et alChinese Critical Care Medicine,;Therapeutic effects of combined admiinistration of halfdose of dexamethasone and anisodamine on severe hem-orrhagic shook[J];CHINESE CRITICAL CARE MEDICINE;1995-06
4 SU Pixiong *, GUAN Yingpeng, YOU Bin, et al. * Heart Center, Beijing Chaoyang Hospital,Beijing 100020;Stereological studies of myocardium in different types of rheumatic vavular diseases[J];Chinese Journal of Thoracic and Cardiovaescular Surgery;2000-06
5 YIN Wen, LIANG Ji-he, CAI Chun, et al. Department of Emergency,Xijing Hospital Fourth Military Medical University, Xi'an 710032,China [;Effect and significance of Anisodamine on tumor necrosis factor-α in acute lung injury[J];CHINESE JOURNAL OF CRITICAL CARE MEDICINE;2000-01
6 JIANG Lan, ZHAO Xiu-Mei, TIAN Niu, LIU Yu-Ying, LI Xiang-Hong, JIANG Chao-Guang Lab of Microcirculation, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing (100853);Simulation study of hemodynamic of small intestinal villosity microvessels in vitro[J];CHINESE JOURNAL OF PATHOPHYSIOLOGY;1999-01
7 Zhu Yu, et al Department of Pathophysiology, Beijing Medical University, Beijing;Studies on antishock action of anisodamine—Effect on liver lysosome stability[J];Chinese Journal of Pahophysiology;1988-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved