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《CHINESE JOURNAL OF THE CARDIAC FUNCTION》 1996-04
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A study on correlations between endothelin level and parameters of cardiac function in coronary heart disease

Liu Wanxia 1, Pei Zhuguo 2 1 Department of Nuclear Medicine , Qingdao Municiple Hospital, Qingdao 266011 2Department of Nuclear Medicine, The Second Affiliated Hospital, China Medical University, Shenyang 110003  
Plasma endothelin(ET) of 48 patients with coronary heart disease (CHD) and 22 normal subjects were determined by radioimmunoassay(RIA).All the values were compared with parameters obtained from radionuclide ventriculography.The results showed that ET level of CHD patients increased significantly and their cardiac functoin parameters were different from that of normal subjects.There were marked correlations between ET level and four of the parameters (left ventricular ejectin fraction, peak ejecfion rate, peak filling rate, and time of peak filling). Therefore we come to the conclusion that the determination of ET level by RIA is significant for diagnosisof heart failure in CHD and evaluation of cardiac function.
【CateGory Index】: R541.4
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