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《Chinese Journal of Cardiovascular Medicine》 2002-04
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Effects of L-Arginine on the Endothelin in plasma and Local Angiotensin II in the hypertrophic heart in rats with renovascular hypertension

Zhang Chang e' Dan Jian xin Deparment of Pathophysiology, Xianning Medical College,Xianning,437100  
Objective To investigate the effects of L Arginine(L Arg) on the Endothelin (ET) in plasma and local AngiotensinII(ArgII) in the hypertrophic heart tissue in rats with renovascular hypertension. Methods The ET in plasma and local AngⅡ in the heart tissue were measured by radioimmunoassay. Results After eight weeks of treatment, The ET in plasma and local AngⅡ in the hypertrophic heart tissue could be significantly decreased by AngⅡ( P 0.01). Conclusion The ET in plasma and local AngⅡ in the hypertrophic heart tissue could be decreased by L AngⅡ.
【CateGory Index】: R544.14
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