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《Xinjiang Agricultural Sciences》 2004-03
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The Studies on Fermentation of L-Serine

FU Jian-hong,CUI CHun-sheng,XIE Yu-qing,LI CHen-hua (Microbial Application Institute of Xinjiang Agriculture Sciences Academy,Urumqi 830000,China)  
S112 is a mutant strain of anti-serine structural analogue and deficient in decomposition ability which produces1.6 g/l serine.In shaking culture test that initial sugar 50 g/l and supplemental sugar 40 g/l after fermenting 37 hours could increase production about 50%. Supplemental nitrogen test in batch culturd indicate that the difference in serine production isn't apparent between simultaneous supplemental sugar nitrogen and single supplemental sugar.The phenomenon suggests that the strain of serine-producing doesn't need much nitrogen.10% fish powder hydrolyzate is optimal by screening fermentation culture medium. The strain began to produce serine after 46 hours culture under no supplemental sugar. The serine production is roughly the same after fermenting 46 h、54 h、58 h、62h、66 h and 72 h which is 1.8 g/l.
【Fund】: 国家"十五"重要科研项目(2001BA708B02-03)
【CateGory Index】: Q93-33
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