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Changes of pathology and fibronectin in corneal alkaline burn in rabbits

ZHANG Luo, QIU Liang Xiu, SHEN Yuan Ping  
Objective To investigate the changes of pathology and fibronectin(FN) in corneal alkaline burn and to explore the clinical effects of FN.Methods Pathohistologic and immumohistochemical assay were used to observerve the changes of cornea in rabbit model after alkaline burn.Results Corneal ulcer occured in 10 eyes 5~11 day later, and corneal perforation occurred in 5 eyes 7~12 days later.After alkaline burn,FN increased in cornea coincide which was identical to the reaction of tissues.Conclusion FN is involved in the whole course of corneal alkaline burn and play a role of rehabilitation and treatment.
【CateGory Index】: R779.1
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