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《Recent Advances In Ophthalmology》 2005-02
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Effects of electric acupuncture to the neurotransmitters of rabbit visual cortex

LIU Wen-Zhou,DUAN Jun-Guo,ZHOU Hua-Xiang,JIANG Wen-Shan,CHEN Xiao-LiFrom the Department of Ophthalmology,the Fifth Hospital of PLA,now he is a MD in Chengdu University of T.C.M),Yinchuan 750004,Ningxia Autonomous Region,China;Department of Ophthalmologic Laboratory of Chengdu University of T.C.M,Chengdu 610075,Sichuan Province,China;Department of Ophthalmology,West-South Hospital of the Third Military Medical University,Chongqing 400038,China;Department of Acupunture and Moxibustion of Chengdu University of T.C.M,Chengdu 610075,Sichuan Province,China  
Objective To investigate the effects and mechanisms of electric acupuncture on neurotransmitters of the rabbit visual cortex and the visual function.Methods To separate 36 rabbits average into three groups:Hegu point group,Taixi point group and normal group.Stimulate the Hegu point and Taixi point 15 minutes,kill the rabbit immediately,and isolate the visual cortex under low temperature.To analyze odd amine transmitters (5-HT,NA,DN) by fluorescence spectrophotometer,determine the cholinesterase by Ellman method.Results The activity of cholinesterase increased after stimulation of acupuncture point of Taixi and Hegu,compare them with the normal group,the difference was remarkable (P0.01).The NA,DA,5-HT increased by stimulating the Hegu point.Compare it with the normal group,the difference was very preeminent(P0.01),the changes of NA,5-HT were not clear,while DA increased by stimulating the Taixi point,compare it with the normal group,the difference was prominent (P0.05).Conclusion Electric acupuncture can cause the change of neurotransmitters in the rabbit visual center,such as the increasing of the activity of cholinesterase,the NA,DA,5-HT and the effects are point specified.
【Fund】: 国家自然科学基金资助 (编号 :39470 866)~~
【CateGory Index】: R245
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