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《Chinese Journal of Human Sexuality》 2014-01
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Tumor markers in differential diagnosis of benign and malignant ovarian tumors

ZHU Xiaolin;LI Yuyan;ZHAO Limei;LUO Yanmei;YAN Ping;LIANG Zhiqing;Department of Obstetrics and Gynecology,Zhuji Center Hospital;Department of Obstetrics and Gynecology,Southwest Hospital;  
Objectives: To analyze the role tumor markers plays in the diagnosis of benign and malignant tumors and to provide the theory basis for the diagnosis of ovarian tumors. Method: 171 cases of OT inpatients admitted into our hospital from September 2007 to March 2010 were selected and divided into two groups,the benign group( n = 94) and the malignant group( n = 77). 80 healthy women were chosen as the control group. Differences in the level of tumor markers were compared among the subjects in the three groups. Results: The tumor marker levels of CA125,CA153,CA199,CA242,CEA and ferritin of the OT group were significantly higher than that of the control group; tumor marker levels of patients with the malignant tumor were significantly higher than those with benign tumor( P 0. 05). The levels of NSE,β- HCG,AFP,PSA,f- PSA and HCG showed no statistical difference in the three groups( P 0. 05). In the malignant group,the positive rate of CA125,CA153,CA199, CA242,CEA,ferritin,β- HCG,AFP and HGH was significantly higher than those in the benign group and control group,with significant statistical difference( P 0. 05). Conclusion: Tumor markers of CA125,CA199, CA242,CEA,ferritin,β- HCG,AFP and HGH play a useful role in the OT diagnosis of benign and malignant tumors. The higher level and positive rate of the tumor markers indicate more advanced OT development and higher risk of malignant tumors. The combined test of CA125,CA199 and CEA can obtain good detection effect with less cost,which is worthy of wide clinical application.
【Fund】: 中国青年科学基金项目(31101058)
【CateGory Index】: R737.31
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