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《Chinese Journal of Animal and Veterinary Sciences》 1990-01
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A STUDY ON TOXICITY OF OXYTROPIS OCHROCEPHALA IN GOATS

Wang Kai ( Oinghai Animal Science and Veterinary Medicine College ) Cao Guangrong, Duan Dexian, Li Shaojun, Gao Juxing ( Northwestern University of Agriculture )  
10g/kg B.W/day Oxytropis ochrocephala power was given to 5 goats via permanent fistula of the rumen, respectively, for study the toxicity of Oxytropis ochrocephala in goats. On the 18-22th day of test, goats appeared neural signs: depression, staring eyes, ataxia, leg weakness, hind quarter paralysis, recumbency and oliguria.On the 33-65th days, the goats died.In lab examinations, liver function tests showed obvious changes: the GOT activity and icterus index in serum increased, α-mannosidase activity in plasma decreased'oligosaccharide excretion increased in urine. Alkaloids was found in urine, MHb and GSH-peroxidase in blood did not change. The major patho-histological lesions were vacuo-lar degeneration in cerebellum Purkinje and Pancreas gland cells, and granular degeneration in hepatic and renal tubular epithelial cells. The results of experiment eliminate the possibility that Oxytropis ochroceph-ala poisoning was due to its excessive selenium and aliphatic Nitro-compounds, and proved that the toxic principles of Oxytropis ochrocephala might be indolizidine alkaloid.lt is assumed that the key factor of poisoning is the activity of α-mannosidase suppressed by the alkaloid.
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【References】
Chinese Journal Full-text Database 10 Hits
1 Ding Boliang; Wang Jianchen; Xue Dengmin; Wang Shue(Dept. of Veterinary Science, Northwestern Agric. University, Yangling, Shaanxi, China 712100);The Detection of Swainsonine From Oxytropis Kansuensis and Urine, Placental Fluid and Fetoplacenta of Poisoned Dairy Goats[J];Acta Agrestia Sinica;1994-02
2 LU Ping1,ZHAO Meng-li2,HAN Guo-dong2(1.College of Life Science and Technology,Inner Mongolia Normal University,Huhhot 010022,China;2.College of Ecological and Environmental Science,Inner Mongolia Agricultural University,Huhhot 010018,China);Hazards and utilization on toxicity of Oxytropis glabra[J];Pratacultural Science;2009-03
3 SHEN Ming-hua1,MO Chong-hui1,ZHAO Bao-yu2,WANG Zhan-xin2(1.College of Agriculture and Animal Science,Qinghai University,Xining,Qinghai,810006,China;2.College of Veterinary Medicine,Northwest A & F University,Yangling,Shaanxi,712100,China);Clinical Symptoms and Pathomorphological Observation of Experimental Oxytropis kansuensis Poisoning in Rabbits[J];Progress in Veterinary Medicine;2010-01
4 Zhao Baoyu Cao Guangrong Tong Dewen (College of Animal Science and Veterinary Medicine Northwestern Agricultural University,Yangling,Shaanxi 712100) Wang Kai Mo Chonghui (College of Agricultural and Animal Husbandry Qinghai University;Preliminary Research of “Jifang C” Preventing Oxytropis Kansuensis Poisoning in Goats[J];PROGRESS IN VETERINARY MEDICINE;1999-01
5 DOU Guo-jun(Station of Veterinary Medicine of Qieji Country,Hainan Prefecture,Qinghai Province,Qieji,813000);Toxicity test of Oxytropis latibracteata in Sheep[J];Chinese Qinghai Journal of Animal and Veterinary Sciences;2004-04
6 SHEN Xiu-ying et al (Qinghai Academy of Animal and Veterinary Sciences,Xining,810016);Pathological Observation of Sheep Poisoned Experimently by Oxytropis ltibracteata jurta[J];Chinese Qinghai Journal of Animal and Veterinary Sciences;2007-02
7 ZHAO Jian-jun (Servise Centre of Animal and Veterinary Technique of Ledu County,Qinghai Pravincl,Ledu,810700);Effect of Adding Oxytropis on Infusorian Numbers in Rumen of Sheep[J];Chinese Qinghai Journal of Animal and Veterinary Sciences;2008-02
8 YANG Xiao-ping (The Library of Wuhan Institute of Science and Technology, Wuhan Hubei 430073, China);Clinical Symptoms of Toxicosis in Animals by Crazyweed[J];Journal of Wuhan Textile S.h.t. Institute;2002-03
9 ZHAO Bao-yu1,2,DONG Qiang1,SHI Zhi-cheng2,MO Chong-hui3,WANG Kai4(1.Institute of Eco-toxicology,Northwest University,Xi′an 710069,China;2.College of Animal Science and Veterinary Medicine,Northwest A & F University,Yangling 712100,China;3.Agriculture andAnimal Husbandry College of Qinghai University,Xining 810006,China;4.Foshan University of Technology,Foshan 528000,China);The comparative research of preventing locoweed poisoning between "Fengcaoling detoxication slow release pill" and "Locoweed toxin vaccine"[J];Journal of Northwest University(Natural Science Edition);2010-06
10 MA Yan-mei, ZHOU Wen-ming, YANG Xin-juan(College of Life Sciences, Northwest A & F University, Yangling, Shaanxi 712100, China);Advances in the Research of Chemical Constituents and Pharmacology of Oxytropis[J];Journal of Northwest Forestry University;2005-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LI Quan,LI Jun-nian,TAO Shuang-lun,DING Yu-jing,HE Lan,WANG Zheng(College of Biology and Environmental Sciences, Jishou University, Jishou 416000, China);Research progress on toxicity, harm and prevention of Oxytropis[J];Pratacultural Science;2009-04
2 WU Xu-jin~(1),YANG Ming-qi~(1),BAI Chun-li~(2),ZHOU Hong-chao~(1) (1.College of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi,712100,China; 2.Yulin Agriculture School,Shaanxi Province,Yulin,Shaanxi,719000,China);Progress in the Method for Swainsonine Source and Separating Method[J];Progress In Veterinary Medicine;2005-05
3 Yang Minqi Cao Guangrong Li Shaojun Gao Feng Wang Anfu (Department of Veterinary Seience,Northwestern Agricultural University);A Study on Inhibition of Mice with Tumor S 180 and ARS by Swainsonine[J];PROGRESS IN VETERINARY MEDICINE;1998-02
4 SHAO Shu-xun~(1,2,3),ZHENG Bao-shan~(2),WANG Ming-shi~(4),LI Xiao-yan~(5),LIU Xiao-jing~(2),LING Hong-wen~(2),LUO Chong~(4)(1.State Key Laboratory of Ore Deposit Geochemistry,Institute of Geochemistry, Chinese Academy of Sciences,Guiyang 550002,China;2.State Key Laboratory of Environmental Geochemistry,Institute of Geochemistry,Chinese Academy of Sciences,Guiyang 550002,China;3.Graduate School of Chinese Academy of Sciences,Beijing 100049,China;4.College of Natural Resources and Environment,Henan University of Sciences and Engineering,Jiaozuo 454000,China;5.Science College of Geobiology,Guizhou Normal University,Guiyang 550001,China);ENVIRONMENTAL GEOCHEMISTRY OF SE AND DISCUSSION OF THE CAUSE OF LIVESTOCK POISONING RESULTING FROM POISONOUS GRASS IN THE HEXI CORRIDOR[J];Acta Mineralogica Sinica;2006-04
5 CHEN Shao-shu1,ZHAO Bao-yu1,GAO Rui2,LI Rong1 (1.College of Animal Sci-Tech,Northwestern Sci-Tech University of Agriculture and Forestry,Yangling, Shaanxi 712100,China;2.Department of Animal Engineering,Yang Ling Vocational and Technical College,Yangling,Shaanxi 712100,China);THE PROGRESS IN RESEARCH OF SWAINSONINE IMMUNOGENICITY AND ANTICANCER-ACTIVITY[J];Natural Product Research and Development;2004-01
6 TAN Yuan-you WANG Jian-hua LI Qing-fan GAO Ju-xing HONG Zi-li an Qing-hong;Acute Toxicity Sections Screened out from Fragments Extracted from Glacial Crazyweed(Oxytropis Glacialis)[J];Journal of Wuhan Textile S.h.t. Institute;2001-01
7 MA Yan-mei, ZHOU Wen-ming, YANG Xin-juan(College of Life Sciences, Northwest A & F University, Yangling, Shaanxi 712100, China);Advances in the Research of Chemical Constituents and Pharmacology of Oxytropis[J];Journal of Northwest Forestry University;2005-02
8 ZHANG Li,YANG Ming-qi,ZHOU Hong-chao,PU Peng,CAO Guang-rong(College of Animal Science and Technology,Northwest Sci-Tech University of Agriculture and Forestry,Yangling,Shaanxi 712100,China);The study of SW in the metabolism product of Rhizoctonia leguminicola[J];Journal of Northwest Sci-Tech University of Agriculture and Forestry;2003-06
9 FAN Yue-yuan,ZHAO Bao-yu,FAN Ze-feng,WANG Yin-chao,TAN Cheng-jian(College of Animal Science and Technology,Northwestern A & F University,Yangling,Shaanxi,712100,China);Systematic pre-experiment on chemical composition and preminary analyse on alkaloids of Astragalus variabills Bunge(yellow flower)[J];Journal of Northwest Sci-Tech University of Agriculture and Forestry(Natural Science Edition);2006-04
10 Zhao Baoyu, Cao Guangrong, Duan Dexian, Li Shaojun ( Department of Veterinary Science, Northwestern Agricutural University ) Lu Xike, Wang Junbiao ( Bureau of Animal Husbandry, Tibet );A STUDY ON TOXICITY OF ASTRAGALUS STRICTUS IN GOATS IN TIBET[J];Chinese Journal of Animal and Veterinary Sciences;1992-03
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Hui-zhen,WU Yi-ming,WU Yong-jun,et al (Department of Environmental Health,College of Public Health ZhengzhouUniversity,Zhengzhou450052,China);Study on the Toxicity of the Water Extract from the Pulp of Cornus[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-03
2 HUANG Wen1) SHI Bi2) (1)Dept. of Environmental Engineering, College of Environmental Sci ences, Peking University; The Key Lab of Water and Sediment Sciences,Ministry of Education, Beijing, 1008 71;2)The Key Lab of Leather Chemistry and Engineering of Mini stry of Education, Sichuan University, Chengdu,610065);Characters of Valonia Tannin Degrading-Enzymes from Endomyces[J];Acta Scicentiarum Naturalum Universitis Pekinesis;2003-04
3 YAN Hai-yan(Dept.Chem.& Chem.Engn.,Baoji Univ.Arts & Sci.,Baoji 721007,Shaanxi,China);Study on structure and biological activity of two flavones from Oxytropis falcata bunge[J];Journal of Baoji University of Arts and Sciences(Natural Science Edition);2008-02
4 Wang Hongwu Tang Minyan Sun Lingfeng (Department of Chemistry,Jiangxi Normal University,Nanchang 330027);The Alkaloids with Antineoplastic Activities[J];JOURNAL OF JIANGXI NORMAL UNIVERSITY (NATURAL SCIENCES EDITION);1996-03
5 Ding Boliang; Wang Jianchen; Xue Dengmin; Wang Shue(Dept. of Veterinary Science, Northwestern Agric. University, Yangling, Shaanxi, China 712100);The Detection of Swainsonine From Oxytropis Kansuensis and Urine, Placental Fluid and Fetoplacenta of Poisoned Dairy Goats[J];Acta Agrestia Sinica;1994-02
6 ZHANG Li rong, XU Da qing, LIU Da qun (College of Plant Protection, Agricultural University of Hebei, Baoding 071001, China);SSR marker, ISSR marker and their application to plant genetics and breeding[J];Journal of Agricultural University of Hebei;2002-01
7 XI Linqiao1, MA Liping2(1. Pratacultural College, Gansu Agricultural University, Lanzhou 730070;2. Library,Gansu Agricultural University, Lanzhou 730070);Current Research Progress on Grassland Poisonous Weeds Oxytropis[J];Grassland and Turf;2003-03
8 Zhao Huaidei Ji Yonglian (Forage and Feed Extension Station of Gansu Province,Lanzhou);THE PRINCIPAL TOXIC AND UNWANTED SPECIES ON GANSU GRASSLANDS[J];Pratacultural Science;1990-04
9 Sahedula·Huoman (Xinjiang Academy of Animal Sciences, Wulumuqi, 830002);ACHNATHERUM INEBRIAS AND ITS PREVENTED AND CURED MEASURES[J];Pratacultural Science;1992-05
10 WU Da, SI Hongli, WANG Jianhua(College of Animal Science and Veterinary Medicine,Northwest SciTec University of Agriculture and Foresty, Yangling,Shaanxi, China, 712100);Study on Locoweed[J];Pratacultural Science;2003-02
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 WANG Lan-feng et al(College of Animal S & T,Northwest A & F University,Yangling,Shaanxi 712100);Identification of a TMPD Degrading Bacterium Staphylococcus pasteuri LF-2[J];Journal of Anhui Agricultural Sciences;2007-12
2 DUO Jie-cuo(Guinan Veterinary Station of Qinghai Province,Guinan,Qinghai 813100);Study on the Dynamic Changes of Serum Protein Content in Sheep after Tentative Poisoning by Oxtropis ochrocephala Bunge.[J];Journal of Anhui Agricultural Sciences;2008-17
3 SHI Dong-fang et al(Central Laboratory of Changchun Normal University,Changchun,Jilin 130032);Preliminary Study on the Isolation and Purification of Active Secondary Metabolites in the Fermentation Broth of Embellisia oxytropis[J];Journal of Anhui Agricultural Sciences;2009-33
4 XI Linqiao1, MA Liping2(1. Pratacultural College, Gansu Agricultural University, Lanzhou 730070;2. Library,Gansu Agricultural University, Lanzhou 730070);Current Research Progress on Grassland Poisonous Weeds Oxytropis[J];Grassland and Turf;2003-03
5 WANG Bao-hai1,CIREN Duo-ji1,WANG Jing-long1,ZHAO Bao-yu2,ZHA Luo1,XIU Hua1(1.Tibet Academy of Agricultural and Animal Husbandry Sciences Lasa 850009,China;2.College of Animal Sciences and Technology,Northwest Sci-Tec University of Agriculture and Foresty,Yangling 712100,China);Research progress of locoweed in Tibet[J];Grassland and Turf;2009-04
6 WU Da, SI Hongli, WANG Jianhua(College of Animal Science and Veterinary Medicine,Northwest SciTec University of Agriculture and Foresty, Yangling,Shaanxi, China, 712100);Study on Locoweed[J];Pratacultural Science;2003-02
7 YU Yong-tao,GENG Guo-xia,LIU Zhi-bin,ZHAO Xing-hua,WANG Jian-hua(College of Animal Sci-Tech,North-West Sci-Tech University of Agriculture and Forestry,Yangling 712100,China);Progress in the study of Oxytropis serioopetala poisoning in domestic animals[J];Pratacultural Science;2006-05
8 LI Li,TONG De-wen,LIU Wen-ming,XING Ming-hui,ZHAO Jun(College of Animal Science and Technology,Northwest A & F University,Yangling 712100,China);Current status of the study of plant toxin immunity[J];Pratacultural Science;2006-06
9 FAN Ze-feng,ZHAO Bao-yu,FAN Yue-yuan,WANG Yin-chao(College of Animal Sci-Tech,Northwestern Sci-Tech University of Agriculture and Forestry,Yang-ling 712100,China);Advances in research of the poisonous fraction and control of Tibet Oxytropis glacialis[J];Pratacultural Science;2006-09
10 TAN Chen-hu (General Grassland Station of Gansu Province, Lanzhou 730046, China);Distribution, harms and control measures of the main poisonous plants in the natural grassland of Gansu province[J];Pratacultural Science;2006-12
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