Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Acta Veterinaria et Zootechnica Sinica》 2006-05
Add to Favorite Get Latest Update

Determination of Residual Avermectins in the Cattle Liver Using HPLC with Fluorescence Detection

HOU Xiao-lin~1,HE Ji-hong~(1,2),DU Xiang-dang~(1,3),SHEN Jian-zhong~(1*)(1.Department of Pharmacology and Toxicology,College of Veterinary Medicine,China Agricultural University,Beijing 100094,China;2.China Animal Husbandry Industry Co.Lid., Beijing 100070,China;3.Department of Pharmacology and Toxicology,College of Husbandry and Veterinary,Henan Agricultural University,Zhengzhou 450002,China)  
A method using high-performance liquid chromatography(HPLC) with fluorescence detection was presented for the simultaneous measurement of the eprinomectin,avermectin,doramectin and ivermectin in liver.Samples were extracted with acetonitrile and cleaned up using solid phase extraction on alumina-B and C_(18) column,and followed by derivatization with acetic anhydride and 1-methylimidazole in acetonitrile.The optimum time required for the completion of derivation reaction of the 4 drugs was 100 min at 96℃.Mean recoveries of the 4 drugs in bovine liver ranged from 70.02% to 88.75%.The intra-and inter-day variations were less than 8.52% and 7.13% respectively.The limit of detection was 0.4-0.5 μg/kg,and the limit of quantitation of the method was 2 μg/kg for all of the 4 drugs.The procedure provides a reliable and sensitive method for routine residual analysis.
【Fund】: 国家杰出青年科学基金资助项目(30325032)
【CateGory Index】: S859.84
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 10 Hits
1 WEN Hao;ZHOU Xu-zheng;LI Bing;NIU Jian-rong;WEI Xiao-juan;ZHANG Ji-yu;Lanzhou Institute of Husbandry and Pharmaceutical Sciences,Chinese Academy of Agricultural Sciences/Key Laboratory of New Animal Drug Discovery,Ministry of Agriculture;;Research progress on the detection of the residue of avermectins[J];黑龙江畜牧兽医;2015-21
2 Zhang Yongbing;Ding Jinmei;He Juan;Environmental Monitor Center of Taizhou Muniicipal;Jiangsu Environmental Protection Key Laboratory of Monitoring for Organic Pollutants in Soil;;Determination of Avemectin in Soil by ASE-Pre-column Derivation-UPLC Method[J];广东化工;2014-04
3 Lu Zhixiao~1 Ju Su~2 Liu Peihai~1 Yang Liming~1 (l.Rizhao Entry-Exit Inspection and Quarantine Bureau, Rizhao 276826; 2.Lan shan agency of Shandong Entry-Exit Inspection and Quarantine Bureau, Rizhao 276808);Oasis HLB purification and determination of avermectin residues in frozen shrimp by UPLC-MS/MS[J];现代仪器;2011-06
4 LI Zaixing1,2,*,ZUO Jian'e1,WU Chunxu1,ZHANG Jingxuan3,LI Hui3,JU Panpan2,YU Xin1 1.School of Environment,Tsinghua University,Beijing 100084 2.School of Environmental Science and Engineering,Hebei University of Science and Technology,Shijiazhuang 050018 3.China National Center for Quality Supervision and Test of Environmental Protection Products,Shijiazhuang 050015;Determination of avermectin in pharmaceutical wastewater by rapid resolution liquid chromatography-tandem mass spectrometry[J];环境科学学报;2011-09
5 LIAN Hui-feng1,SONG Jie1,ZHANG Wen-juan2,SONG Huan1(1.Shanxi Border Inspection and Quarantine Bureau,Taiyuan 030024,China; 2.College of Life Science,Shanxi University,Taiyuan 030006,China);Study on the Development Method of Avermectins Residue in Food Determination[J];山西农业科学;2011-08
6 YIN Jing-jing,LU Hong-da (College of Fishery and Life Science,Shanghai Ocean University,Shanghai 201306,China);RP-HPLC Determination of Residual Amounts of Abamectin in Muscle Tissues of Shrimps[J];理化检验(化学分册);2011-03
7 LI Lin-xia,CUI Yao-wen,SHEN Jian-zhong,FENG Pei-sheng, WU Hai-xia,CHENG Lin-li,ZHANG Su-xia(College of Animal Medicine,China Agricultural University,Beijing 100193,China);Determination of Moxidectin residue in pork by HPLC-FLD[J];中国农业大学学报;2011-01
8 PENG Zhang-xiao1,JIANG Min1,2,WU Hao1,HE Lin1,YANG Li1(1.Key Laboratory of Aquatic Genetic Resources and Aquacultural Ecology Certificated by the Ministry of Agriculture,Shanghai Ocean University,Shanghai 201306,China;2.Research and Engineering Center on Aquatic Environment Ecosystem,Shanghai Ocean University,Shanghai 201306,China);Research on the method for ivermectin determination in different crucian tissues[J];水产学报;2010-06
9 CHEN Jing1,LUO Yong-huang2,FU Li-zhi1(1.Chongqing Academy of Animal Sciences,Chongqing 402460;2.College Pharmacy Sciences,Southwest University,Chongqing 400716;China);Multi-residue Determination of Avermectin and Ivermectin in Grass Carp Muscle Tissues by HPLC[J];中国兽药杂志;2009-12
10 ZHAO Wei-dong1, ZHENG Wen-jie1,, HE Yan1, WAN Yu-ping2, WANG Shan-liang2(1.Tiangjin Entry-Exit Inspeation and Quarantine Bureau of China, Tianjin 300201, China;2.Beijing Wanger Biotechnology Co., Ltd, Beijing 102206, China);DETECTING AVERMECTINS RESIDUES IN ANIMAL PRODUCT USING ENZYME LINKED IMMUNOSORBENT ASSAY[J];食品研究与开发;2009-04
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Liu Lili;Liu Qian;Zhou Yang;Baoding Branch of Inspection and Quarantine Technical Center, Hebei Entry-Exit Inspection and Quarantine Bureau;;Optimization of Instrument Conditions in Determination of Abamectin Residues by LC/ MS/MS Spectrometry[J];农药科学与管理;2014-03
2 YANG Jun-hong;HE Ji-hong;HOU Xiao-lin;QI Peng;WU Jia-xin;China Animal Husbandry Group;China Animal Husbandry Industry Company Limited;Beijing University of Agriculture;;Determination of Residual Avermectins in the Cattle Muscle Using IAC-HPLC with Fluorescence Detection[J];中国畜牧兽医;2014-01
3 Li Ming;College of Life Science,Daqing Normal University;;Research Advances of Avermectins Toxicology[J];安徽农学通报;2013-20
4 ZHANG Wen-Juan1,LIAN Gen-yin2,GUO Xiao-xi2,YANG Xiao-lan1,SONG Huan2,(1.College of Life Science,Shanxi University,Taiyuan 030006,China;2.Shanxi Border Inspection and Quarantine Bureau,Taiyuan 030024,China);Determination of Avemectin Residues in 10 Foods by Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry[J];食品科学;2012-18
5 JIA Bian-tao,LIU Peng-yan,JIA Hu,LIU Hui-ping(Agronomy College,Shanxi Agricultural University,Taigu 030801,China);Bioactivity Comparison of 10 Insecticides against Diamondback Moth(Plutella xylostella L)[J];山西农业科学;2011-01
6 LI Zeng-Mei 1,DENG Li-Gang1,ZHAO Shu-Fang2,GUO Chang-Ying1, ZHAO Shan-Cang1,MAO Jiang-Sheng1,WANG Yu-Tao1 1 (Inspection Center of Food Quality (Jinan) Ministry of Agriculture,Jinan 250100) 2 (Mushroom Workstation of Shandong Province,Jinan 250102);Determination of Abamectin in Apples and Soil by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry[J];分析化学;2010-10
7 CHENG Lin-li1,AN Hong-ze2,SHEN Jian-zhong1,CAO Bin-bin1,HUANG Xing-hua1 (1.College of Veterinary Medicine,China Agricultural University,Beijing 100193,China;2.China Institute of Veterinary Drug Control,Beijing 100081,China);Rapid HPLC for quantitation of 4 kinds of avermectin residues in milk[J];中国农业大学学报;2010-04
8 ZHANG Kan-kan,HU De-yu,ZHANG Yu-ping,LU Ping,ZENG Song,SONG Bao-an,HUANG Rong-mao,GUO Qing-qing(Research and Development Center for Fine Chemicals,State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering,Key Laboratory of Green Pesticide and Agricultural Bioengineering,Ministry of Education,Guizhou University,Guiyang 550025,China);Residue and decline study of emamectin benzoate in rice field[J];农药学学报;2010-02
9 WU Zhi-xiong1,HU Jiang-tao2,ZHENG Wei-dong3,SHENG Yi2,CHEN Si1,YIN Wen-ya1.1.Department of Nutrition and Food Hygiene,West China School of Public Health,Sichuan University,Chengdu 610041,China;2.Sichuan Entry-Exit Inspection and Quarantine Bureau,Chengdu 610041,China;3.Sichuan Institute of Product Quality Supervision & Inspection,Chengdu 610031,China;Determination of Avermectin and Ivermectin in Swine Muscular Tissues Using High Performance Liquid Chromatography-tandem Mass Spectrometry[J];四川大学学报(医学版);2010-03
10 ZHANG Hui-xia,HU De-yu,LU Ping,JIAO Yang,LI Fei-fei,LUO Hong-min,HUANG Rong-mao(Center of Research and Development of Fine Chemicals,Guizhou Uinversity,Guiyang 550025,China);Determination of Abamectin Residue in Cabbage by HPLC[J];农药;2010-03
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 ZHOU Zun-wu;HE Fang-yang;WAN Yu-ping;FENG Jing;CUI Ting-ting;Shandong Spring Snow Food Co.,Ltd.;Beijing Kwinbon Biotechnology Co.,Ltd.;Beijing Engineering Research Centre of Food Safety Immunodetection;;Determination of Abamectin Residues in Vegetables by Enzyme-linked Immunosorbent Assay[J];现代农业科技;2015-21
2 WEN Hao;ZHOU Xu-zheng;LI Bing;NIU Jian-rong;WEI Xiao-juan;ZHANG Ji-yu;Lanzhou Institute of Husbandry and Pharmaceutical Sciences,Chinese Academy of Agricultural Sciences/Key Laboratory of New Animal Drug Discovery,Ministry of Agriculture;;Research progress on the detection of the residue of avermectins[J];黑龙江畜牧兽医;2015-21
3 Liu Ying;Wu Xiaoping;Su Lifang;Wang Wenjun;Chen Yinhui;Beijing Entry-Exit Inspection and Quarantine Bureau;Beijing WDWK Biotechnological Corporation Ltd;;Establishment of Pretreatment method for the Determination of Avermectins in Milk[J];检验检疫学刊;2015-04
4 Wang Aiping;Pei Yanyan;Zhou Jingming;Li Pengfei;Zhao Jinmeng;Chen Fei;Che Zhifen;Qi Yanhua;College of Life Science,Zhengzhou University;;Preparation and Identification of the Artificial Antigen of Ivermectin[J];中国农学通报;2015-17
5 ZHAO Jian;XU Xiu-qin;LV Yan;WU Yin-liang;YANG Ting;Ningbo Academy of Agricultural Sciences in Zhejiang Province;;Simultaneous Determination of 32 Drugs in Water Body by Ultra-high Performance Liquid Chromatography-Tandem Mass Spectrometry[J];江西农业学报;2014-07
6 WU Xu-jin;LI Meng;ZHOU Ling;MA Jing-wei;WANG Hong;ZHANG Jun-feng;Henan Key Laboratory of Grain Quality and Safety and Testing,Research Center of Agricultural Quality Standards and Testing Techniques,Henan Academy of Agricultural Sciences;;Residue and Degradation Analysis of Abamectine in Cotton and Soil[J];河南农业科学;2014-03
7 WEI Xin-Xin;DOU Cai-Yun;DUAN Yong-Sheng;MA Yu-Song;Hebei Entry-Exit Inspection and Quarantine Bureau;;Determination of avermectin residues in dried chili by HPLC with fluorescence detection[J];食品安全质量检测学报;2013-06
8 FU Qiang;YANG Renbin;ZHENG Liguo;YANG Yumei;LIU Mengjia;College of Resource and Environment,Hunan Agricultural University;Hunan Reseach Institue of Chemical Industry;;Stability of trifluro acetamide derivative products of abamectin and emamectin benzoate[J];农药学学报;2013-06
9 BAO James Jianmin1,2,XIE Dan1,2,SUN Chaohui1,LI Youxin1*,WANG Junju3(1.Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency,School of Pharmaceutical Science and Technology,Tianjin University,Tianjin 300072,China;2.Tianjin ASD Scientific Co.,Ltd.,Tianjin 300452,China;3.Tianjin Institute of Veterinary Drugs and Feed Control,Tianjin 300402,China);Preparation of a hydrophilic-lipophilic composite solid phase extraction material and application in food safety inspection[J];色谱;2013-09
10 RUAN Jiming;HU Kun;YANG Xianle;ZHANG Haixin;WANG Yi;ZHOU Ailing;ZHAO Yini;Shanghai Ocean University, National Pathogen Collection Center for Aquatic Animals;College of Animal Sciences and Technology, Jiangxi Agricultural University;Jiangxi Fisheries Research Institute;;Blood-brain barrier permeability and residual tissue characteristics of Avermectin(AVM) in Carassius auratus gibelio[J];中国水产科学;2013-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved