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《Chinese Journal of Animal and Veterinary Sciences》 2012-03
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Detection of CN and DUMPS Carriers in Holstein Bulls and Pedigree Analysis

XIE Yan1,FAN Xue-hua1,WU Xiao-ping1,ZHANG Yi1,LIU Lin3,GONG Wei-jia2, CHEN Shao-hu2,SUN Dong-xiao1,ZHANG Sheng-li1,ZHANG Yuan1(1.College of Animal Science and Technology,China Agricultural University,Beijing 100193, China;2.Dairy Data Processing Center,Dairy Association of China,Beijing 100085,China; 3.Beijing Dairy Cattle Center,Beijing 100085,China)  
The aim of the present study was to detect the proportion of Holstein bull carrying two recessive genetic defects including citrullinemia(CN) and deficiency of uridine monophosphate synthase(DYMPS) and carry out the pedigreed analysis,a more easier diagnostic method was developed as well.The genetic defects of CN and DYMPS was detected by PCR-RFLP in 591 Holstein bulls,and the AS-PCR technology was constructed for detecting the CN recessive deleterious gene.2 CN carrier bulls and 1 DUMPS carrier bull were found,and the proportion of carrier bulls was 0.34% and 0.17%,respectively.Through pedigree analysis,the two CN carrier bulls were the descendants of Linmack Kriss King,and the DUMPS carrier bull was Skokie sensation Ned's offsprings.The results indicate that it is necessary to establish early monitor system on genetic defects in all Holstein young,proven bulls and suspect cows,and put such information in their pedigree records.Through young bull pre-selection and selection and assortative mating system,carrier bulls could be avoided to enter into the national genetic improvement program,frequencies of the undesired recessive alleles could be greatly decreased as well.
【Fund】: 国家自然科学基金(31072016);; 农业部“948”项目(2006-G48;2011-G2A);; 高等学校博士学科点专项科研基金(20070019044);; 教育部新世纪优秀人才支持计划;; 转基因生物新品种培育重大专项(2009ZX08009-156B);; “十二五”国家科技支撑项目(2011BAD28B02)
【CateGory Index】: S823
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【References】
Chinese Journal Full-text Database 1 Hits
1 CHU Qin 1,JIAO Shi-Hui 2,WANG Ya-Chun 2,LIU Lin 3,LIU Ai-Rong 4,WU Hong-Jun 5,XIE Zhen-Quan 6,HOU Shi-Yu 6,GENG Fan-Jun 7,WANG Cong-Yong 7,HUANG Xi-Xia 8,TAN Shi-Xin 9,TAN Rui 10,ZHANG Yi 2,YU Ying 2,ZHANG Yuan 2 1.Institute of Animal Husbandry and Veterinary Medicine,Beijing Academy of Agriculture and Forestry Sciences,Beijing 100097,China;2.Key Laboratory of Agricultural Animal and Breeding,National Engineering Laboratory for Animal Breeding,College of Animal Science and Technology,China Agricultural University,Beijing 100193,China;3.Beijing Dairy Cattle Centre,Beijing 100192,China;4.Hailaer Farm Buro,Hailaer 021008,China;5.Xiertala Breeding Farm,Hailaer Farm Buro,Hailaer 021008,China;6.Anshan Hengli Dairy Farm,Anshan 114200,China;7.Dingyuan Seedstock Bulls Breeding Ltd.Company,Zhengzhou 450046,China;8.College of Animal Science,Xinjiang Agricultural University,Urumqi 830052,China;9.Xinjiang Tianshan Animal Husbandry Bio-engineering Co.Ltd,Changji 831109,China;10.Xinjiang General Livestock Service,Urumqi 830009,China;Establishment of the detection method for two causative genes of cattle arachnomelia syndrome[J];Hereditas;2013-05
【Citations】
Chinese Journal Full-text Database 3 Hits
1 ZHOU Yue-jun(College of Animal Science and Technology,Northwest A&F University,Yangling,Shaanxi 712100,China);Research Progress on Monogenic Disorders in Dairy Cattle[J];China Cattle Science;2010-05
2 Li Jianbin1 Wang Hongmei1 Gao Yundong1 Zhang Xiuhong2 Li Yanqin Zhong Jifeng1(1Dairy Cattle Research Center,Shandong Academy of Agricultural Sciences,Jinan 250100;2Shandong Ox Biotechnology CO,.LTD,Jinan 250100);Detection of an Inherited Defect:Citrullinemia by PCR-RFLP in Chinese Holstein Dairy Cattle[J];Biotechnology Bulletin;2006-06
3 WEI Yu-chun1,LIU Chou-sheng2,WANG Xin-zhuang3,WANG Zhi-gang2,SUN Xiu-zhu2,HAN Xu2(1 College of Veterinary Medicine,Northwest A&F University,Yangling,Shaanxi 712100,China;2 National Animal Husbandry & Veterinary Service of the Ministry of Agriculture(MOA),Beijing 100193,China;3 College of Animal Science and Veterinary Medicine,Henan Agricultural University,Zhenzhou,Henan 450000,China);Detecting Citrullinemia in Holstein Calves using PCR-SSCP analysis[J];Journal of Northwest A & F University(Natural Science Edition);2009-08
【Co-citations】
Chinese Journal Full-text Database 6 Hits
1 ZHOU Li1,2,JIA Guang-le1,ZHANG Ying2,HAN Xue-qing1,LIN Xiang-mei1(1.Chinese Academy of Inspection and Quarantine,Beijing 100121,China; 2.College of Animal Science and Technology,Shanxi Agricultural University,Taigu 030801,China);Progress on the Study of the Test Methods for Bovine Leukocyte Adhesion Deficiency(BLAD)[J];China Animal Husbandry & Veterinary Medicine;2012-02
2 WEI Yu-chun1,LIU Chou-sheng2,WANG Xin-zhuang3,WANG Zhi-gang2,SUN Xiu-zhu2,HAN Xu2(1 College of Veterinary Medicine,Northwest A&F University,Yangling,Shaanxi 712100,China;2 National Animal Husbandry & Veterinary Service of the Ministry of Agriculture(MOA),Beijing 100193,China;3 College of Animal Science and Veterinary Medicine,Henan Agricultural University,Zhenzhou,Henan 450000,China);Detecting Citrullinemia in Holstein Calves using PCR-SSCP analysis[J];Journal of Northwest A & F University(Natural Science Edition);2009-08
3 DONG Tian,SUN Dong-xiao,ZHANG Yi,ZHANG Sheng-li,ZHANG Yuan (College of Animal Science and Technology,Key Laboratory of Animal Genetics and Breeding of Ministry of Agriculture, China Agricultural University,Beijing 100193);Research Advances of Clotting Factor Ⅺ Deficiency in Dairy Cattle[J];China Dairy Cattle;2011-08
4 YANG Chao1,ZHANG Yi1,SHI Wan-hai2,CHEN Shao-hu3,ZHANG Sheng-li1,ZHANG Yuan1(1.College of Animal Science and Technology,China Agricultural University,Beijing 100193;2.Beijing Dairy Cattle Center,Beijing 100192;3.Data Center of China Dairy Association,Beijing 100192);Establishment of a Genotype Database for Genetic Testing Using Microsatellites in Chinese Hostein Bulls[J];China Dairy Cattle;2011-16
5 DONG Tian1,XIE Yan1,SUN Dong-xiao1,ZHANG Yuan1,ZHANG Sheng-li1,ZHANG Yi1,LIU Lin2,CHEN Shao-hu3(1.College of Animal Science and Technology,China Agricultural University;Key Laboratory of Animal Genetics and Breeding, Ministry of Agriculture,Beijing 100193;2.Beijing Dairy Cattle Centrer,Beijing 100192;3.Data Center of China Dairy Cattle,Beijing 100192);Identification of Factor XI Deficiency in Dairy Cattle[J];China Dairy Cattle;2011-22
6 LI Qiang1,ZHANG Yi1*,WANG Ya-chun1,WU Meng2,XU Xian-zhou2, ZHANG Zhi-jun2,SUN Dong-xiao1,YU Ying1,ZHANG Sheng-li1,ZHANG Yuan1(1.Key Laboratory of Animal Genetics,Breeding and Reproduction of Ministry of Agriculture, College of Animal Science &Technology,China Agricultural University,Beijing 100193,China; 2.Snowdragon Beef Co.,Ltd.,Dalian 116031,China);Molecular Diagnosis and Allele Frequency of the Insertion of 15 Nucleotides in Bovine Factor XI Gene[J];Chinese Journal of Animal and Veterinary Sciences;2013-08
【Co-references】
Chinese Journal Full-text Database 6 Hits
1 LI Rong-Ling1,ZHANG Gui-Xiang2,WANG Zhi-Gang2,WANG Hui1,Han Xu2,WANG Dong-Lei3,WANG Jun-Hui4 1.College of Animal Science and Technology,Shandong Agricultural University,Tai’an 271018,China 2.National Center of Preservation and Utilization of Genetic Resources of Domestic Animals and Forage,National Animal Husbandry and Veterinary Service,Beijing 100094,China 3.College of Animal Science and Technology,Yangzhou University,Yangzhou 225009,China 4.College of Animal Science and Technology,Northwest Sci-Tech University of Agriculture & Forestry,Yangling 712100,China;Analysis of the genetic structure of 12 Chinese and foreign cattle breeds using DNA microsatellite markers[J];Hereditas;2007-12
2 JIAO Shi-Hui,WANG Ya-Chun,ZHANG Yuan National Engineering Laboratory for Animal Breeding,Department of Animal Science and Technology,China Agricultural University,Beijing 100193,China;Arachnomelia syndrome:a skeletal system malformation inherited disorder[J];Hereditas;2011-01
3 Sun Yi,Sun Dongxiao,Zhang Yuan(Department of Animal Genetics and Breeding,China Agricultural University,Beijing 100094);Identification of Bovine Leukocyte Adhesion Deficiency in Chinese Holstein[J];China Dairy Cattle;2007-11
4 JIAO Shi-hui1,TIAN Yue-zhen2,Norbia·Wbuli2,WU Hong-jun3,LIU Ai-rong4,ZHANG Sheng-li1,HUANG Xi-xia2, WANG Ya-chun2,ZHANG Yuan1(1.College of Animal Science and Technology,China Agriculture University,Beijing 100193;2.College of Animal Science and Techonology,Xinjiang Agriculture University,Uromqi 830052;3.Breeding Cow Farm of Inner Mongolia Xieertala,Hulunbeier 021008; 4.Inner Mongolia State Hailar Farms Group Co.Ltd,Hulunbeier 021008);Establishment of Molecular Detection Methods for Arachnomelia Syndrome in Brown Swiss Cattle[J];China Dairy Cattle;2011-10
5 CHENG Ben-yi,XIA Jun-hui,GONG Jun-yi,YANG Shi-hua (China National Rice Research Institute,Hangzhou 310006,China);Application of Capillary Electrophoresis Detection with Fluorescent SSR Markers in Rice DNA Fingerprint Identification[J];Chinese Journal of Rice Science;2011-06
6 YIMING XIaili 1,WANG Ya-chun2,HUANG Xi-xia1*,TIAN Ke-chuan3,TIAN Yue-zhen1,GUO Jun-qing4,TAN Shi-xin5,FU Xue-feng3,YIBULAYIMU Re yilai1(1.College of Animal Science and Techonology,Xinjiang Agriculture University,Urumqi 830052,China;2.College of Animal Science and Technology,China Agriculture University,Beijing 100193,China;3.Xinjiang Academy of Animal Scienc,Urumqi 830000,China;4.Breeding Cow Farm of Urumqi,Urumqi 830049,China;5.Tianshan Animal Husbandry Bio-engineering Co.Ltd,Changji,Xinjiang 831109,China);The Genetic detection of arachnomelia syndrome in the breeding group of Xinjiang brown cattle[J];Chinese Journal of Veterinary Science;2012-09
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 Li Jianbin1 Wang Hongmei1 Gao Yundong1 Zhang Xiuhong2 Li Yanqin Zhong Jifeng1(1Dairy Cattle Research Center,Shandong Academy of Agricultural Sciences,Jinan 250100;2Shandong Ox Biotechnology CO,.LTD,Jinan 250100);Detection of an Inherited Defect:Citrullinemia by PCR-RFLP in Chinese Holstein Dairy Cattle[J];Biotechnology Bulletin;2006-06
2 LI Qiu-ling~1,XU Shang-zhong~2,ZAN Lin-sen~1,GAO Xue~2,ZHANG Zheng-feng~1,REN Hong-yan~2,CHEN Jin-bao~2(1 College of Animal Science and Technology,Northwest A & F University,Yangling,Shaanxi 712100,China;2 Institute of Animal Science,Chinese Academy of Agriculture Science,Beijing 100094,China);Study on polymorphisms of part sequence of intron 5 and exon 6 of bovine UCP3 gene[J];Journal of Northwest Sci-Tech University of Agriculture and Forestry(Natural Science Edition);2006-11
3 LI Yan-Hua,ZHANG Sheng-Li,HAN Guang-Wen,XUE Jian-Hua,ZHAO Peng Beijing Dairy Cattle Center,Beijing 100085,China;A method for detecting bovine leukocyte adhesion deficiency in Hol-stein calves using polymerase chain reaction-single strand conforma-tion polymorphism analysis[J];Hereditas;2007-12
4 WANG Hong-Mei, LI Jian-Bin, HOU Ming-Hai, WANG Chang-Fa, LI Qiu-Ling, ZHONG Ji-Feng Dairy Cattle Center of Shandong Academy of Agricultural Sciences, Ji’nan 250100, China;The development and application of method for detecting bovine complex vertebral malformation[J];Hereditas;2008-09
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