Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Animal Science and Veterinary Medicine》 2014-02
Add to Favorite Get Latest Update

Effects and Efficacy Assessment of Su-Kang Detoxification Oral Liquid on Astragalus Strictus Poisoned Rabbits

HAO Bao-cheng;YANG Xian-peng;WANG Xue-hong;LIU Jian-zhi;WANG Bao-hai;GUO Wen-zhu;GUO Zhi-ting;LIU Yu;SHANG Ruo-feng;HU Yong-hao;LIANG Jian-ping;Key Laboratory of New Animal Drug Project,Gansu Province/Key Laboratory of Veterinary Pharmaceutics Discovery,Ministry of Agricultural/Lanzhou Institute of Husbandry and Pharmaceutical Sciences of ,CAAS;Institute of Animal Husbandry and Veterinary,Tibet Academy of Agricultural and Animal Husbandry Sciences;College of Veterinary Medicine,Gansu Agricultural University;  
Astragalus was fed artificially to 2-month-old experimental rabbits to cause poisoning.Three experimental groups were set including control group,intoxication group,detoxification treatment group,each group with four experimental rabbits,to establish poisoning and detoxification pathological model.On 28-d(poisoning death),45-d(poisoning death) and 49-d(detoxification and control groups were sacrificed),pathological changes of rabbits were investigated and the effect of oral treatment of Su-Kang detoxification were evaluated.The results demonstrated on 18-d detoxification treatment group the rabbits occurred poisoning symptom,on 28-d dead rabbits were found in intoxication group,on 29-d detoxification treatment group was cured by Su-Kang oral liquid,none dead rabbit was found,which showed that the model was established successfully.Pathology slices observations showed that the organs of the intoxication group rabbits showed serious pathological changes such as congestion,inflammation,necrosis and so on,the detoxification treatment group showed mild gore,mild cell degeneration.Therefore,the Su-Kang detoxification oral solution can effectively improve theα-mannose glycosides enzyme activity and detoxifying group test rabbits exhibited mild pathological changes,it confirms that the Su-Kang detoxification oral solution has good detoxifying effect.
【Fund】: 国家高新技术研究发展计划(863计划)课题编号:2011AA10A214;; 中央级公益性科研院所基本科研业务费专项资金(项目编号:1610322012001);; 西藏横向委托项目:预防动物疯草中毒解毒新制剂的研制(2011-2013)
【CateGory Index】: S859.87
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 7 Hits
1 ZHAO Bao-yu1,2,DONG Qiang1,SHI Zhi-cheng2,MO Chong-hui3,WANG Kai4(1.Institute of Eco-toxicology,Northwest University,Xi′an 710069,China;2.College of Animal Science and Veterinary Medicine,Northwest A & F University,Yangling 712100,China;3.Agriculture andAnimal Husbandry College of Qinghai University,Xining 810006,China;4.Foshan University of Technology,Foshan 528000,China);The comparative research of preventing locoweed poisoning between "Fengcaoling detoxication slow release pill" and "Locoweed toxin vaccine"[J];Journal of Northwest University(Natural Science Edition);2010-06
2 ZHAO Baoyu1,WANG Baohai2,MO Chonghui3,DONG Qiang1,GE Luo4,ZHA Luo2,XIU Hua2,TU Deng5 and SUO Duo6(1.Northwest A&F University,Yangling Shaanxi 712100,China;2.Academy of Agriculture and Grazing,Lasa 850000,China;3.College of Agriculture and Grazing,Qinghai University,Xining 810016,China;4.Extension Station of Husbandry Technology in Agricultural and Grazing Hall of Tibet,Lasa 850000,China;5.Veterinary Station of Gaize County in Ngari Prefecture,Gaize Tibet 859000,China;6.Agricultural and Grazing Bureau in Ngari Prefecture,Gar Tibet 85900,China);The Disaster Survey of the Oxytropis glacialis Poisoning in Livestock in the Ngari of Tibet[J];Acta Agriculturae Boreali-Occidentalis Sinica;2011-04
3 Zhao Baoyu, Cao Guangrong, Duan Dexian, Li Shaojun ( Department of Veterinary Science, Northwestern Agricutural University ) Lu Xike, Wang Junbiao ( Bureau of Animal Husbandry, Tibet );A STUDY ON TOXICITY OF ASTRAGALUS STRICTUS IN GOATS IN TIBET[J];Chinese Journal of Animal and Veterinary Sciences;1992-03
4 ZHAO Bao_yu1, TONG De_wen1, GE Peng_bin2, DONG Qiang1, Mo Chong_hui3(1.Animal Sci-Tech College ,Northwest Sci-Tech University of Agriculture and Forestry,Yangling,Shaanxi,712100,China;2.Yangling Danong Bio_Tech Co.,LTD,Shaanxi,712100;3.College of Agriculture and Animal Husbandry Qinghai University,Xining Qinghai 810003,China):Grassland of China,No.4,2003,pp.65~68.;Locoweed Harm Investigation in the West Grassland of China[J];Grassland of China;2003-04
5 LI Jian-ke (College of Life Science, Shaanxi Normal University, Xi'an 710062);The Present Situation and Prospect of the Studies on Locoweed in China[J];Scientia Agricultura Sinica;2003-09
6 ZHAO Bao-yu1, LIU Zhong-yan1, WAN Xue-pan1, HUO Xing-hua1, GUO Xi1, WANG Jiang-jun1, LIU Zhong-yan1, SUN Li-sha1, SHI Zhi-cheng2 (1College of Veterinary Medicine, Northwest A&F University, Yangling 712100, Shaanxi; 2Eco-toxicology Institute, Northwest University, Xi’an 712100, Shaanxi);Damage and Control of Poisonous-Weeds in Chinese Western Grassland[J];Scientia Agricultura Sinica;2008-10
7 ZHOU Qi-wu,ZHAO Bao-yu,LU Hao,WANG Shan-shan,ZHANG Liang,WEN Wei-li,YANG Xiao-wen(College of Veterinary Medicine,Northwest A&F University,Yangling 712100,Shaanxi);The Research and Control Situation of Ecology and Animal Poisoning of Locoweed in Western Natural Grassland of China[J];Scientia Agricultura Sinica;2013-06
Chinese Journal Full-text Database 10 Hits
1 DUO Jie-cuo(Guinan Veterinary Station of Qinghai Province,Guinan,Qinghai 813100);Study on the Dynamic Changes of Serum Protein Content in Sheep after Tentative Poisoning by Oxtropis ochrocephala Bunge.[J];Journal of Anhui Agricultural Sciences;2008-17
2 ZHAO Jian-xi et al(Institute of Nutrition and Food Hygiene,School of Public Health,Lanzhou University,Lanzhou,Gansu 730000);Acute Toxicity of Oxytropis kansuensis Bunge on Rats[J];Journal of Anhui Agricultural Sciences;2011-31
3 HAO Bao-cheng et al(Key Laboratory of New Animal Drug Project,Key Laboratory of Veterinary Pharmaceutics Discovery,Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS,Lanzhou,Gansu 730050);Research Advances in the Detoxificating Preparation of Swainsonine in "Locoweed" and Its Application to Anti-tumor[J];Journal of Anhui Agricultural Sciences;2012-05
4 Ding Boliang; Wang Jianchen; Xue Dengmin; Wang Shue(Dept. of Veterinary Science, Northwestern Agric. University, Yangling, Shaanxi, China 712100);The Detection of Swainsonine From Oxytropis Kansuensis and Urine, Placental Fluid and Fetoplacenta of Poisoned Dairy Goats[J];Acta Agrestia Sinica;1994-02
5 GUO Wei,LI Qin-fan,KONG Xiang-ya,REN Jie,JING Xin-tang(College of veterinary medicine,Northwest A&F University,Yangling,Shaanxi Province 712100,China);Optimal C/N Ratio for Producing Swainsonine(SW) Using Locoweed Endophytes FEL3[J];Acta Agrestia Sinica;2011-04
6 XI Linqiao1, MA Liping2(1. Pratacultural College, Gansu Agricultural University, Lanzhou 730070;2. Library,Gansu Agricultural University, Lanzhou 730070);Current Research Progress on Grassland Poisonous Weeds Oxytropis[J];Grassland and Turf;2003-03
7 WANG Bao-hai1,CIREN Duo-ji1,WANG Jing-long1,ZHAO Bao-yu2,ZHA Luo1,XIU Hua1(1.Tibet Academy of Agricultural and Animal Husbandry Sciences Lasa 850009,China;2.College of Animal Sciences and Technology,Northwest Sci-Tec University of Agriculture and Foresty,Yangling 712100,China);Research progress of locoweed in Tibet[J];Grassland and Turf;2009-04
8 WU Da, SI Hongli, WANG Jianhua(College of Animal Science and Veterinary Medicine,Northwest SciTec University of Agriculture and Foresty, Yangling,Shaanxi, China, 712100);Study on Locoweed[J];Pratacultural Science;2003-02
9 YU Yong-tao,GENG Guo-xia,LIU Zhi-bin,ZHAO Xing-hua,WANG Jian-hua(College of Animal Sci-Tech,North-West Sci-Tech University of Agriculture and Forestry,Yangling 712100,China);Progress in the study of Oxytropis serioopetala poisoning in domestic animals[J];Pratacultural Science;2006-05
10 FAN Ze-feng,ZHAO Bao-yu,FAN Yue-yuan,WANG Yin-chao(College of Animal Sci-Tech,Northwestern Sci-Tech University of Agriculture and Forestry,Yang-ling 712100,China);Advances in research of the poisonous fraction and control of Tibet Oxytropis glacialis[J];Pratacultural Science;2006-09
China Proceedings of conference Full-text Database 3 Hits
1 PANG Long,LU Hao~*,ZHAO Bao-Yu~*,ZHANG Liang,SONG Yan-Yan,Wang Shan-Shan, Zhao Yi-Nan (College of Veterinary Medicine,Northwest A&F University,YangLing 712100,China);The morphological changes of cerebral cortical neurons by swainsonine in neonatal SD rat in vitro culture[A];[C];2011
2 LU Hao,LU Wei,ZHAO Bao-Yu,RONG Jie,CHENG Ji-Ping,PANG Long,SONG Yan-Yan (College of Veterinary Medicine,Northwest A&F University,YangLing 712100,China);Isolation and Identification of Endophytic Fungus from the serious locoweed of China[A];[C];2011
3 Bao-cheng HAO 1,Xian-peng YANG 1,2,3,Xue-hong WANG 1,Yu LIU 1,Xue-hu LI 2,Zhi-jun XIN 2,Jian-ping LIANG 1,2 (1.Key Laboratory of New Animal Drug Project,Gansu province /Key Laboratory of Veterinary Pharmaceutics Discovery,Ministry of Agricultural /Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS,PR China,Lanzhou 730050;2.Institute of Modern Physics,Chinese Academy of Sciences,Lanzhou Gansu 730000,China;3.Chinese Academy of Sciences,Beijing 100049,China);Study on Optimization of Extraction Technology of Swainsonine from Astragalus strictus with the microwave-assisted extraction method Based on GC[A];[C];2012
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 LEI Qian et al(Key Laboratory of Ecosystem Model and Application,State Ethnic Affair Commission,The North University for Ethnics, Yinchuan,Ningxia 750021);Study on the Relationship between the Poisonous Plants in Northwest Ethnic Regions and Ethnoecology[J];Journal of Anhui Agricultural Sciences;2009-28
2 WANG Bao-hai1,CIREN Duo-ji1,WANG Jing-long1,ZHAO Bao-yu2,ZHA Luo1,XIU Hua1(1.Tibet Academy of Agricultural and Animal Husbandry Sciences Lasa 850009,China;2.College of Animal Sciences and Technology,Northwest Sci-Tec University of Agriculture and Foresty,Yangling 712100,China);Research progress of locoweed in Tibet[J];Grassland and Turf;2009-04
3 DONG Qiang1,ZHAO Baoyu1,TONG Dewen1,GE Pengbin2,Hasibatu3,DA Nengtai3,LIU Tuya3,SU Yile3(1 College of Animal Science, Northwestern Agriculture and Forestry University, Yanglin, 712100,Shanxi; 2 Yanglin Danong Biotechnology corporation, Ltd, Yanglin, 712100, Shanxi;3 AlashanVeterinary sanitation supervision Center, Alashan prefecture, 750300, Inner Mogolia);Poisonous weeds investigation on natural grassland in Alashan prefecture[J];Pratacultural Science;2003-06
4 LI Chunjie, GAO Jiahui, MA Bin(College of Pastoral Agriculture Science and Technology, Lanzhou University; Gansu Grassland Ecological Research Institute, Lanzhou 730020 , China);Seven diseases of drunken horse grass (Achnatherum inebrians) in China[J];Pratacultural Science;2003-11
5 LIU Ying, LONG Rui-jun, YAO Tuo (Pratacultural Institute, Gansu Agricultural University, Lanzhou 730070, China);Research progress on Stellera chamaejasme L. in grassland[J];Pratacultural Science;2004-06
6 TAN Chen-hu (General Grassland Station of Gansu Province, Lanzhou 730046, China);Distribution, harms and control measures of the main poisonous plants in the natural grassland of Gansu province[J];Pratacultural Science;2006-12
7 TANG Tao1,LI Yu-ling2,ZHOU Qing-ping2(1.Qinghai University,Xining 810016,China;2.Qinghai Academy of Animal Science and Veterinary Medicine,Xining 810016,China);The preliminary research on Oxytropis ochrocephala rust in alpine meadow around Qinghai lake[J];Pratacultural Science;2007-04
8 MA Song-jiang(Integrated Service Station of Pratacultural Industry of Geermu City,Geermu 816000,China);The poisonous and harmfulness plant resource in grassland and its economy value in Haixi of Qinghai Province[J];Pratacultural Science;2008-05
9 Ma Haibo Wu Yujun Ma Weidong (Alashan Zuoqi Grassland Station, Inner Mongolia, Bayanhaote 750300);THE POISONOUS PLANTS IN ALASHAN NATURAL GRASSLAND[J];PRATACULTURAL SCIENCE;1996-06
10 She Yongxing Ji Suling Tian Fayi (Department of Animal Husbandry and Veterinary Medicine, Tibetan Agriculture and Animal Husbandry College, Linzhi 860000);THE MAIN POISONOUS PLANTS AND THEIR CONTROL IN THE NATURAL GRASSLAND OF TIBET[J];PRATACULTURAL SCIENCE;1997-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved