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《Animal Husbandry & Veterinary Medicine》 2008-12
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Level of MDA and activities of SOD and GSH-Px in the chickens infected with avian infectious bronchitis virus

WANG Hai-feng1,ZHONG Xiu-hui1,2,LI Qing-yan2,GUO Bing3,WANG Hai-long1,DU Jian2,NI Yao-di2(1.College of Animal Science and Technology,Hebei Agricultural University,Baoding 071001,China;2.College of Traditional Chinese Veterinary Medicine,Hebei Agricultural University,Dingzhou 073000,China;3.College of Animal Science and Technology,Hebei North University,Zhangjiakou 075000,China)  
To investigate the changes of serum oxidative indexes in chickens infected with avian infectious bronchitis virus(IBV),80 chickens of 15-day-old were divided into control and experimental group.Birds in experimental group were infected with IBV by nasal inoculation.The superoxide dismutase(SOD)and glutathione peroxidase(GSH-PX)activities and malonaldehyde(MDA)contents were detected in the sera from each group at days 1,3,6,9 and 12 after infection,respectively.The results showed that compared with control group,SOD and GSH-Px activities in experiment group significantly decreased after infection(P0.05 or P0.01);MDA contents increased after infection and were significantly higher than those of control group at days 6 and 9 after infection(P0.01).It suggested that oxidative damage might participate in the occurrence and development of avian infectious bronchitis.
【Key Words】： infectious bronchitis virus serum SOD GSH-PX MDA
【CateGory Index】： S858.31
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