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《Medical Journal of National Defending Forces in Southwest China》 2008-04
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Effects of transcatheter arterial chemoembolization(TACE) followed by radiofrequency(RF) hyperthermia on treatment of advanced liver carcinoma

LUO Yi-zhou,LIAO Hui,HUANG Huang,LIU Man-jia,SHI Bin-bin,LI Zi-he Hospital 454 of PLA,Nanjing,210002.  
Objective:To reveal the effects of transcatheter arterial chemoembolization(TACE) combined with radiofrequency(RF) hyperthermia on advanced liver carcinoma.Methods:33 cases of advanced liver carcinoma were divided into two groups,the TACE+RF hyperthermia group including 14 cases and other 19 cases in the TACE group.All cases were treated by TACE and the cases in TACE+RF hyperthermia group were followed by RF hyperthermia.The response rates of both groups were evaluated after 3 courses of treatment according to WHO criteria.The grades of liver function were compared before and after therapy and the bone marrow suppression rate was determined according to WHO standards.Results:In TACE+RF Hyperthermia group,3 cases achieved partial response(PR,21.4%) and 5 cases SD(35.7%).In TACE group,2 cases PR(15.8%) and 3 cases stabilization(SD,15.8%).The disease control rate(PR+CR+SD)was 51.7%(TACE+RF Hyperthermia group) verse 26.3%(TACE group,P0.05);There were no difference in liver function and blood marrow suppression rate between two groups(P0.05).Conclusion:TACE followed by RF hyperthermia has a better disease control rate than single TACE treatment and the adverse effects were similar between two groups.
【Fund】: 南京军区医药卫生科研项目(06MA71)
【CateGory Index】: R735.7
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