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Effect of Point Application in Dog Days on Serum IgE,IL-4,IFN-γ in Patients with Allergic Rhinitis

LIN jia-jing1,2,HE Xiao-hua1,HU Yu-hua1,WANG Yan-cheng2,SUN Bo-jian2,HAN Mei2(1.The Affiliated Traditional Chinese Hospital of Ningxia Medical University,Yinchuan 750001;2.Department of Pathogenic Biology and Immunology of Ningxia Medical University,Yinchuan 750004)  
Objective To observe the effect of traditional chinese medicine(TCM) point application in dog days on serum IgE in patients with allergic rhinitis.Methods Patients with allergic rhinitis were treated by traditional chinese medicine point application in dog days.The levels of total IgE,IL-4 and IFN-γ in serum were assayed by radioimmunoassay in 32 patients with allergic rhinitis and 46 healthy subjects came from health examination.Results Total serum IgE and IL-4 significantly increased in allergic patients compared with controls(P0.01),and there were no significant difference of serum IFN-γ between cases and controls.After treatment using point application,total serum IgE in allergic patients decreased significantly(P0.05),but the levels of IL-4 and IFN-γ showed no difference between two groups(P0.05).Conclusion Traditional chinese medicine point application in dog days can reduce the level of serum IgE in AR patients.
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