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《Journal of Xianning Medical College》 2002-04
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Synthesis of Ciprofloxacin Derivatives Containing 2-Methyl-5-Nitroimidazol

YE Fa-qing 1,CHEN Li,YUAN Xin,et al (1.Department of Chemistry,Wenzhou Medical College,Wenzhou Zhejiang 325027,China)  
Objective To study the synthesis of ciprofloxacin derivatives containing 2-methyl-5-nitroimidazol.Methods Ciprofloxacin derivatives containing 2-methyl-5-nitroimidazol were synthesized primarily from 2-methyl-5-nitroimidazol and ciprofloxacin via nucleophilic substitution and esterifying.Results Ciprofloxacin derivatives containing 2-methyl-5-nitroimidazol had been synthesized.Conclusion The structure of these new compounds have been examined and confirmed by IR? 1 H-NMR?MS spectra as well as elementary analysis.
【Fund】: 湖北省教育厅重点课题资助项目 (98B0 33)
【CateGory Index】: TQ465
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