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《Journal of Xianning College(Medical Sciences)》 2004-05
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Protective Effects of Berberine on Myocardium Suffered from Acute Ischemia

FANG Hui,WANG Hui,LI Yang (Department of Pharmacology,School of Medicine,Wuhan University, Wuhan Hubei 430071,China)  
Objective To observe the effects of berbeine on myocardium suffered from acute ischemia in rabbit.Methods With the technique of monophasic action potential to observe the effects on MAP of three-tier myocardium during acute myocardial ischemia and the effects after berberine have been used.Results In the group of berberine,MAPA were changed relative diminutive in comparison with that in the control,and the 2-aspect platform did not disappear fully.The shap of MPA was not triangular.The TDR of three-tier myocardium were depress.The rates of EDA and arrhythm of acute ischemia were dropped markedly.Conclusion Berberine has protective effects on acute myocardial ischemia.
【CateGory Index】: R541
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