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《The Journal of Neonatology》 2004-01
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CHANGES AND SIGNIFICANCE OF PLATELET PARAMETERS IN NEONATAL HYPOXIC - ISCHEMIC ENCEPHALOPATHY

Yang Fengmei, Jia Ronghe, Gao Haibin, et al. Department of Pediatrics, Yang Quan First People's Hospital, Shanxi, 045000, China  
Objective To explore the changel and clinical significance of platelet parameter in neonatal hy-poxic-ischemic encephalopathy(HEI). Methods 102 cases of neonatal HIE were distributed by their clinical severity. The platelet total(PLT), mean platelet volume(MPV) and platelet distribution width (PDW) were observed dynamicly. They were compared with the results of 60 normal newborn infants. Results (1) PLT in acute period of HIE was significanty lower than that of the normal newborn infant ( P 0.01) . MPV and PDW were significantly higher than those of normal newborn infant( P 0.01) . PLT,MPV,PDW in recover period of HIE had no significant difference with normal group(P 0.05). (2) PLT had decreased with the severity of HIE (P 0.01) and MPV,PDW increased( P 0.01, P 0.05) with the severity of HIE. Conclusion Dynamical observation of the platelet parameters can be regarded as an index of evaluating the severity of HIE.
【CateGory Index】: R722.13
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