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《Chinese Journal of Thrombosis and Hemostasis》 2004-01
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Clinical Significance of Coagulation-Anticoagulant and Fibrinolytic in Pregnance Woman

TANG Rong-hua, LIU Fa-hu, KONG Li-na Yijishan Hospital of Waman Medical College, Wuhu 24101, China  
Objective: To test the variation of coagulation-fibrinolytic system in the pregnancy women and pregnancy - induced hypertension women(PIH) ,explore the application of coagulation firinolytic system markers in the pregnancy women. Methods: 63 pregnancy women were divided into two groups: 43 cases of the narmal prgancy women and 20 PIH, according to chnical conditions. The plasma levels of prothrombin time(PT) , activated partial thrombin time(APTT) ,thrombin (TT),fibrinogcn(Fbg) ,free protein S (FPS) were detected by clotting method, D-Dimer (D-D) and vWF by iimmunoturbidity on the coagulation analyzer. Results: In two groups the levels of PT, APTT were signifcantly shorter. The rate of the prolong TT were found in 18% of PIH while only in 1% of the normal pregnancy women; Fbg in two groups showed higher significandy than that in the control group. There are no significant defferenccs plasma level of FPS between the normal pregnancy and the control group but FPS in PIH decreased clearly . A significant change of vWF in two groups were observed , especially in the patients with PIH. Conclusion: The normal pregnancy women and PIH are assoicated with marked activation of coagulation-frobrinolytic endotheliam damage to a certain extent . These markers are useful to evaluate the coagulation-fribrinolytic level of the pregancy women, predict bleeding and protect DIC.
【CateGory Index】: R446.11
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【References】
Chinese Journal Full-text Database 4 Hits
1 ZHU Xin 1 CHEN Tao 2 1.Department of Laboratory,the Central Hospital of Xiangtan City,Hunan Province, Xiangtan 411100,China;2.Department of Laboratory,the First People's Hospital of Changde City,Hunan Province, Changde 415000,China;Four Blood Coagulation Indexes Testing and Analyzing of the Clinical Significanc for Parturient Women[J];中外医疗;2012-35
2 Wu Shao-ying.(Intranet of Guangzhou Women and Children′s Medical Center,510000);Clinical significance of the changes of molecular makers in patients with hypertensive disorders in pregnancy in pre-thrombosis state[J];中国优生与遗传杂志;2012-05
3 Xie Rong-zhang (Department of Laboratory Science,Guangdong Province Municipal People's Hospital of Yunfu,Yunfu 527300,China);Clinical Meaning on Variation of Coagulation Indexes and Anticoagulant Indexes and Fibrinolysis Indexes in Normal Pregnancy Women[J];中国医药导刊;2009-11
4 LING Wan-wen,LIN Jian-hua,LIN Qi-de,ZHANG Wei-yuan(Department of Obstetrics and Gynecology,Renji Hospital,School of Medicine,Shanghai Jiaotong University,Shanghai 200127,China);Change of coagulation function of hypertensive disorders in pregnancy[J];上海交通大学学报(医学版);2008-01
【Citations】
Chinese Journal Full-text Database 1 Hits
1 XU Yong, HUO Mai, XU Hong-binPeople's Hospital, Shanzhen, Guangdong 518020;The Level of Endothelium Damage Markers and Prethrombotic Markers in Pregnancy-Induced Hypertension Women[J];血栓与止血学;2001-02
【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 JIANG Bi-fen,ZHANG Guo-kun(Department of Laboratory,Zhaotong First People′s Hospital,Zhaotong,Yunnan 657000,China);Analysis on coagulation screening results in 148 prepartal women[J];检验医学与临床;2013-06
2 LIU Qian(Department of Clinical Laboratory,Linyi Traditional Chinese Medicine Hospital,Shandong 276003,China);The test result and the clinical value of detecting the function of the blood coagulation for pregnancy women in later terms[J];检验医学与临床;2012-23
3 ZOU Zejun Department of Clinical Laboratory,Panzhihua Maternal and Child Health-Care Hospital in Sichuan Province,Panzhihua 617000,China;The value of coagulation four indices combined platelet detection in patients with pregnancy induced hypertension[J];中国现代医生;2012-25
4 (XU Li-xiao);Observation on Variation of Coagulation in Pregnant Woman[J];血栓与止血学;2005-01
5 TANG Rong-hua, LIU Fa-hu, KONG Li-na Yijishan Hospital of Waman Medical College, Wuhu 24101, China;Clinical Significance of Coagulation-Anticoagulant and Fibrinolytic in Pregnance Woman[J];血栓与止血学;2004-01
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 WEI Xiu-min,MIAO Qin-ling,WANG Su-qin (Department of Obstetrics/Gynecology in Jiyuan People Hospital,Jiyuan 454650,China);Clinical analysis of the formation of DVT after caesarean section based on 14 case studies[J];河南医学研究;2010-03
2 LI Xin-chun,SHA Tong-ye,ZHANG Jing(Trditional Chinese Medicine Hospital of Rizaho City,Rizhao 276800,China);Clinical research of thrombogenesis of deep veins of lower limb after caesarean section[J];泰山医学院学报;2008-01
3 LING Wan-wen,LIN Jian-hua,LIN Qi-de,ZHANG Wei-yuan(Department of Obstetrics and Gynecology,Renji Hospital,School of Medicine,Shanghai Jiaotong University,Shanghai 200127,China);Change of coagulation function of hypertensive disorders in pregnancy[J];上海交通大学学报(医学版);2008-01
4 XIAO Lin,et al(Department of Gynecology and Obstetrics,the Frist Affiliated Hospital,Chongqing Medical University);The relationship between placenta thrombosis and bad outcomes of late pregnancy[J];重庆医科大学学报;2007-11
5 ZHENG Chang-cheng WU Jing-sheng (Department of Hematology,the Provincial Affiliated Hospital of Anhui Medical University,Hefei 230001,China);Inherited Thrombophilia and Adverse Obstetric Outcomes[J];血栓与止血学;2006-04
6 WU Wen-qing, XIE Hong-yan, LU Yi-xia, et al. Department of Obstetrics and Gynecology, Nanshan Affiliated Hospital of Guangdong Medical University, Guangdong 518052, China;Study on the changes of platelet function in patients with hypertensive disorder complicating pregnancy[J];中华围产医学杂志;2006-03
7 YANG Zi, LI Rong, SHI Ling-yi, WANG Li-na, YE Rong-hua, WANG Rong, HUANG Ping. Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100083, China;Clinical delimitation and expectant management of early onset of severe pre-eclampsia[J];中华妇产科杂志;2005-05
8 YE Yuehong,et al (Department of Clinical Laboratory,the Second College of Clinical Medicine,Chongqing Medical University);The study of the activities of antithrombin Ⅲ in several thrombophilia[J];重庆医科大学学报;2004-02
9 TANG Rong-hua, LIU Fa-hu, KONG Li-na Yijishan Hospital of Waman Medical College, Wuhu 24101, China;Clinical Significance of Coagulation-Anticoagulant and Fibrinolytic in Pregnance Woman[J];血栓与止血学;2004-01
10 ZHENG Lei,WANG Qian,SUN Dehua,et al (Nanfang Hospital,The First Military Medical University,Guangzhou Guangdong 510515,China);Detection of Prethrombosis State in Patients with Pregnancy Induced Hypertension and Its Clinical Significances[J];实用妇产科杂志;2003-06
【Secondary References】
Chinese Journal Full-text Database 8 Hits
1 LI Yan;ZHANG Jian;ZHANG Xiaoming;Department of Gynecology,the Second Clinical College of Ji’nan University;;Correlation Analysis of Prethrombotic State and the Early Onset of Severe Preeclampsia[J];医学理论与实践;2014-15
2 Lin Shaomei;Wei Fengying;Liang Lineng;Department of Gynecology,the Maternal and Child Health Hospital of Shunde District;;Anticoagulants combined with calcium and vitamin E in the early intervention of hypertensive disorder complicating pregnancy patients[J];中国基层医药;2014-13
3 DONG Chun-Yu;Department of Gynecology and Obstetrics,Affiliated Hospital of Yanbian University;;Relationship between platelet count,serum globulin and fibrinogen in patients with hypertensive disorder complicating pregnancy[J];中国妇幼保健;2013-35
4 XIONG Yu * ,LOU Yi-ting * ,CAI Xu,XUZheng-fang,ZHOU Rong,YANG Dan,MA Duan,LI Xiao-tian * . * The Obstetrics & Gynecology Hospital,Fudan University,Shanghai 200011,China;Maternal alternations of haemostasis and thrombosis in preeclampsia[J];中国实用妇科与产科杂志;2013-03
5 Wu Shao-ying.(Intranet of Guangzhou Women and Children′s Medical Center,510000);Clinical significance of the changes of molecular makers in patients with hypertensive disorders in pregnancy in pre-thrombosis state[J];中国优生与遗传杂志;2012-05
6 Lin Wen-yuan(Laboratory Dept of the Second People's Hospital in Yichang,Yichang 443000,China);Analysis of Coagulation Index Test Results of 230 Parturient Women[J];中国医药导刊;2012-02
7 ;The effect of whole-range epidural analgesia on blood coagulation function of natural labor in women with hypertensive disorders in pregnancy[J];武警医学院学报;2011-12
8 DING Fang-lin,LIU Cong,LI Li-Wen,LI ZHONG-cheng (Department of Laboratory,Shenzhen Second People's Hospital,Shenzhen,518035,China);Study on the Makers of Thrombus and Platelet Activation in Patients of Hypertensive Disorder Complicating Pregnacy[J];血栓与止血学;2009-03
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 WANG Hui, BAI Jun, HU Zhanghe, et al. First Affiliated Hospital of Hubei Medical University, Wuhan 430060;Clinical Study on Pathologic Changes of Umbilical Cord Vessels in Pregnancy Induced Hypertension[J];中华妇产科杂志;1999-01
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