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《Chinese Journal of Schistosomiasis Contral》 1996-04
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Huang Wentong,Yang Loujing,Tan Peiping,Huang Shan Hunan Institute of Parasitic Diseases (Yueyang 414000)  
The experimental results in the laboratory showed that the mortalities of snails exposed to 5 ?20 mg/L of Rhizoma Paridis saponin for 48 h were 50. 0?00%;and no juvenile snail had been hatched after its eggs were exposed to 12. 5 ?50. 0 mg/L of Rhizoma Paridis saponin for 24 h or over. The mollusciciding effect by spray in the field is lower than that of immersion,A certain toxicity to fish was found when the saponin concentration over 10 mg/ L;and its LD50 to mice was 5 546. 26 mg/kg B. W. in the oral acute toxicity test,and its Ld50 to domestic rabbit was over 2200 mg/kg B. W. in the skin acute toxicity test. It is indicated that this saponin is a kind of slight toxic drug to untarget animal,when it is used as mollusci-cides.
【Fund】: 湖南省中医管理局资助
【CateGory Index】: R184.38
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