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《Chinese Journal of Cardiovascular Research》 2018-03
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Coronary artery bypass grafting combined with mitral valvoloplasty for the treatment of ischemic mitral regurgitation

ZHU Yong-feng;ZHANG Xiang-li;FU Zhi-kun;Department of Cardiovascular Surgery,Zhengzhou Cardiovascular Hospital,Zhengzhou No.7 People's Hospital;  
Objective The aim of this study was to identify the predictors of early prognoses and survivals in patients with ischemic mitral regurgitation(IMR) who had undergone mitral valvuloplasty(MVP) combined with revascularization. Methods From January 2012 to December 2015, 33 patients with IMR who had undergone MVP combined with coronary artery bypass graft(CABG) in our institution were enrolled. Mitral valve annuloplasty rings were used in all patients. Patients' mean age was( 58.3 ±7.7)years,New York Heart Association(NYHA)class Ⅲ or Ⅳ was 51.5%, preoperative left ventricular end-diastolic diameter(LVEDD) was(58.0±4.7)mm and ejection fraction(EF) was(52.3%±11.4)%. The study endpoints were postoperative death, reoperation, recurrence of moderate or severe mitral regurgitation and heart failure. Results Follow-up data were obtained in all patients.Mean follow-up was(20.3±8.5)months. Preoperative characteristics were comparable between the two groups. Only mitral annular dilatation(AD) was significantly different between the groups(57.9% vs. 30.3%, P=0.02). AD,NYH A class Ⅲ or Ⅳ, ventricular aneurysm(VA) were powerful risk factors of endpoint events on univariate analysis. After adjustments, Cox proportional-hazards regression analysis showed that AD, atrial fibrillation, aortic cross clamp time were the risk factors of early prognoses. Moreover, patients with annular dilatation showed significantly higher rate of endpoint events than those without annular dilatation(HR =5.64,95%CI 1.20-28.05, P0.05). Conclusion In patients with IMR, annular dilatation, atrial fibrillation, and long aortic cross clamp time were independent risk factors of early prognoses after MVP combined with CABG. Patients with annular dilatation showed higher rate of endpoint events than those without annular dilatation.
【CateGory Index】: R654.2
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 WU Ruo bin, ZHENG Shao yi, GUO Hui ming, et al. Department of Cardiac Surgery, Guangdong Provincial Cardiovascular Institute, Guangzhou 510100, China;Strategy in treating ischemic mitral regurgitation[J];中华胸心血管外科杂志;2004-05
【Co-citations】
Chinese Journal Full-text Database 6 Hits
1 ZHU Yong-feng;ZHANG Xiang-li;FU Zhi-kun;Department of Cardiovascular Surgery,Zhengzhou Cardiovascular Hospital,Zhengzhou No.7 People's Hospital;;Coronary artery bypass grafting combined with mitral valvoloplasty for the treatment of ischemic mitral regurgitation[J];中国心血管病研究;2018-03
2 YUAN Ning-ning,GAO Chang-qing*,JIANG Sheng-li,REN Chong-lei,SHENG Wei,YAO Ming-hui Department of Cardiovascular Surgery,General Hospital of PLA,Beijing 100853,China;Early effect of surgery for ischemic mitral insufficiency: a report of 46 cases[J];解放军医学杂志;2013-06
3 ZHAO Tie-fu 1,WANG Sheng-yu 1,LIU Dong 1,MA Han-ying 2.(1.Department of Cardiac Surgery,Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,P.R.China;2.Department of Geriatric Cardiology,Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,P.R.China);Treatment Strategy for Patients with Subacute Myocardial Infarction and Severe Ischemic and Functional Mitral Regurgitation[J];中国胸心血管外科临床杂志;2013-02
4 YU Yang,GU Cheng-xiong,LI Jing-xing,LI Hai-tao,GAO Ming-xin.(Department of Cardiac Surgery,Beijing An Zhen Hospital,Capital Medical University,Beijing 100029,P.R.China);Off-pump Surgical Therapy for Mild-to Moderate-Ischemic Mitral Regurgitation Using a Self-designed Device[J];中国胸心血管外科临床杂志;2012-03
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1 HU Shengshou, CHEN Lei, XU Jianping, et al. Department of Cardiac Surgery, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China;Surgical treatment of ischemic mitral regurgitation (an analysis of 38 cases)[J];中华心血管病杂志;2002-11
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