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Effect of honeysuckle in the treatment for peptic ulcer with Hp infection

ZHANG Shi-Lin, HE Xiao-Yan, Zeng Zhong-Qiu and PENG Ji-Xin(Department of Medical Administration, the People's Hospital ofYongshun County, Yongshun 416700, Hunan Province, China)  
AIM To study the effect of honeysuckle in the treatment of peptic ulcer (PU) with H. Pylori (Hp) infection,compared with prnton-pump inhibition (PPl ) triple therapy.METHODS ln 154 active PU petients diagnosed by gastroscopy Hp test was positive in 48 petients (group A), were taken only two pills (30 g/ pill) of self-made honeysuckle capsule; 56 patients (group B), two pills of honeysuckle capsules and 150mg of Ranitidine; 50 patients (group C), 20 mg of omeprazole, 100 mg of amoxicillin and 400 mg of metronidazole. All of them were taken the medicines twice a day after meals. Reexamine was performed one week after 2-3 weeks treatment.RESULTS The total efficacy rates of the three groups were 72. 9%, 92 .8% and 94,0%. The Hp eradication rates were 64 .6%, 87. 5% and 90 .0%. Group C was tbe best of the three and group B was better than group A, group B was almost as the same as group C. boring the treatment only 40% in group C had side effects, Such as nausea and constipation. The cost of two weeks' medicines in RMB was: in group A 4 yuan; group B 10 yuan and groop C 650 yuan. The differences among them were quite obvious.CONCLUSION Honeysuckle and ranitidine in the treatment of Hp+ PU is as effedive as PPl triple therapy.This treatment is safe, cheap and highly effective.
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