Upper gastrointestinal symptoms in type 2 diabetes mellitus and detection of gastric emptying by ultrasongraphy
Chun-Tao Li,Ye Zhang,Department of Digestive Endocrinology,Shunyi District Hospital,China Medical University, Beijing 101300,China
AIM:To investigate the relationship between upper gastrointestinal(GI)symptoms and gastric emptying in patients with type 2 diabetes mellitus. METHODS:A total of 411 patients with type 2 diabetes mellitus were examined in Beijing Shunyi District Hospital from November 2005 to October 2007,and 264 normal individuals were used as controls.We statistically analyzed the rate of GI symptoms and the scores of severity. Ultrasound scan was performed to measure the gastric emptying rate 30,60,90 min after drink- ing water. RESULTS:The rate of GI symtoms in diabetic patients was significantly higher than that in normal controls(60.3%vs 16.7%,P0.01).The most common GI symptoms in diabetic patients were epigastric fullness(77.9%)and abdominal distention or belching(61.1%).The scores ofsymptomic severity were also higher in diabetic patients(P0.01).The gastric emptying in pa- tients with diabetes was delayed as compared with that in normal controls 30,60 and 90 min after drinking water(P0.01).Diabetic patients with normal and delayed gastric emptying in 60 min showed significant differences only in early satiety,nausea and vomiting(P0.05). CONCLUSION:Type 2 diabetic patients have a significantly higher prevalence of upper GI symptoms,and delayed gastric emptying may contribute to these symptoms.Ultrasound is convenient in detecting the gastric emptying of diabetic patients.
【CateGory Index】： R587.2;R445.1