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《Journal of Xinxiang Medical College》 2005-06
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Immunohistochemistry study on collagen type Ⅰand Ⅲ of sternomastoid muscle in congenital muscular torticollis

XUE Ke-xiu~1,YAN Hai-yan~2,LIU Tong-Xi~1 (1.The Third Affiliated Hospital of Xinxiang Medical College,Xinxiang,Henan 453003;2.Zhengzhou Children's Hospital,Zhengzhou,Henan 450053)  
Objective To investigate the expression and hyperplasy of Collagen Type Ⅰand Ⅲ in sternomastoid muscle of congenital muscular torticollis and to explore the pathogenesis of sternomastoid muscle fibrosis.Methods The hyperplastic state of collagen fiber was observed by Masson collagen staining method and immunohistochemical method was performed to investigate the expression of Collagen Type Ⅰ,Ⅲ.Results By Masson collagen staining method,it was observed that the collagen fibers proliferated excessively.In immunohistochemistry,the expression of Collagen Type Ⅰ,Ⅲ in the experimental group is significantly higher than that in the control group(P0.01).Conclusion The degrees of sternomastoid muscle fibrosis in congenital muscular torticollis are related to the hyperplasy of Collagen Type Ⅰ,Ⅲ.
【Fund】: 河南省科技攻关项目(0524410057)
【CateGory Index】: R726.8
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