Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Xinxiang Medical College》 2006-03
Add to Favorite Get Latest Update

Relationship between level of matrix metalloproteinase-1 and soluble CD40 ligand in patients with unstable angina

CAI Lun-an,WEI Jing-han,ZHAO Luo-sha,et al (1.Department of Cardiology,the First Affiliated Hospital to Zhengzhou University,Zhengzhou 450052 China;2.Department of Cardiology,Xinyang Central Hospital,Xinyang 464000 China)  
Objective To analyze the correlation of metalloproteinase-1(MMP-1)and CD40 ligand(CD40L)or MMP-1 and IL-1β,so as to explore the role of expression and secretion of MMP-1 regulated by CD40L on pathophysiologicial mechanism of unstable angina.Methods The serum levels of soluble CD40L,MMP-1 and IL-1β were measured by enzyme-linked immunosorbent assay in 36 patients with unstable angina,24 patients with stable angina and 20 controls.And also the levels of Creactive protein(CRP) were measured by immune-turbidimetry method,and the correlations of MMP-1 and CD40L or IL-1β were analyzed,and to analyze the correlation of MMP-1 and CRP in patients with unstable angina.Results Serum levels of MMP-1,CD40L and IL-1β were significantly higher in patients with unstable angina than those with stable angina(P0.01) and controls(P0.01).MMP-1 level was stronger positively correlated with CD40L in unstable angina(r=0.486,P0.01),MMP-1 was positively weaker correlated with IL-1β(r=0.369,P0.05).Level MMP-1 were positively correlated with CRP in patients with unstable angina(r=0.489,P0.01).Conclusion It is possible reason for the expression and secretion of MMP-1 regulated by CD40 L in the rupture of coronary artery plaque.
【CateGory Index】: R541.4
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 4 Hits
1 ZHOU Hong-juan,KONG Li-hong,YE Yu-wan,CUI Chang-xiang(Hubei University of Chinese Medicine,Wuhan 430061,China);Influences of Medicine and Catgut Embedding In Acupoints On Matrix Metalloproteinase-9 In Cortex Tissues of Rats With Focal Cerebral Ischemia Reperfusion Injury[J];Journal of Hubei University of Chinese Medicine;2009-04
2 GUO Ai-ling1,TIAN Pei-chao2,WANG Huai-li2,ZHUO Zhi-hong2,QIAO Xiao-hui2,CHEN Xiao-xin2(1.Department of Surgery;2.Department of Pediatrics,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China);Expression of Matrix Metalloproteinase 9 and Tissue Inhibitor of Metalloprteinase 1 in Rats with Infectious Brain Edema[J];Journal of Applied Clinical Pediatrics;2008-11
3 KE Hai-xia,JIA Yin-ming,HAN Qin-fu,et al(Department of Cardiovasculary,Anyang People′s Hospital,455000);Relationship between pregnancy-associated Plasma Protein A,C-reactive Protein and metabolic syndrome[J];Journal of Xinxiang Medical College;2008-01
4 MENG Ling-bo1,XU Jian-gong2,SHI Xin-chang1(1.Department of Internal Medicine,Longhai Hospital of Kaifeng City,Kaifeng 475003,China;2.Department of Thoracic Surgery,the Third Affiliated Hospital of Xinxiang Medical College,Xinxiang 453003;China);Effect of low molecular weight heparin calcium and simvastatin on patients with unstable angina pectoris[J];Journal of Xinxiang Medical College;2008-05
Chinese Journal Full-text Database 10 Hits
1 Yu Hai; Liao Xiaoyi; Zhou Zhiyu; et al.(Haikou city peple's hospital, Hainan 570208);EXTRACTION OF COLLAGEN FROM RAT TAIL TENDON AND PREPARATION OF COLLAGEN GEL[J];HAINAN MEDICAL JOURNAL;2000-03
2 MENG Jun,ZHANG Yi,ZHANG Jia-xin,et al.The Third Clinical College of China Three Gorges University,Gezhouba Central Hospital,Yichang 443000,Hubei,P.R.CHINA;Effect of Ginkgo leaf extract/dipyridamole injection on unstable angina pectoris and its possible mechanism.[J];Hainan Medical Journal;2009-12
3 Li Meiying, Yin Minglan, Ni Ming (Pharmacelltical Dosage Department, Second Affiliated Hospital, Hubei Medical Univercity, Wuhan 430071, China);Clinical Application of Subcutaneously Embedded Chinese Herbal Medicine[J];JOURNAL OF HUBEI MEDICAL UNIVERSITY;1998-02
4 YE Shi-wen (Guangdong effort Extension explosive materials plant clinic,Shaoguan 512146);Of traditional Chinese medicine treatment of unstable angina[J];Jilin Medical Journal;2010-15
5 Yu Liya Department of Cardiology, Huadong Hospital, Shanghai 200040, China;CLINICAL STUDY OF EXTRACT OF GINKGO BILOBA LEAVES IN TREATMENT OF PATIENTS WITH UNSTABLE ANGINA[J];Gereatrics & Health Care;2005-01
6 YAO Yiqun,SU Ximin,LIU Fangling(Cadre ward,The General hospital of PLA Beijing Commond,Beijing 100700,China);The relationship between carotid and coronary atherosclerosis by pathologic analysis[J];Chinese Journal of Clinical Healthcare;2007-01
7 FENG Zhen-hua1,JI Xiang-wu2 (1.Master Postgraduate of Grade 2007,Weifang Medical College,Weifang 261042,Shandong,China ;2.Department of Cardiac Medicine,Weifang People's Hospital Affiliated to Weifang Medical College,Weifang 261041,Shandong,China);Clinical Study of Salvianolate in Early Admission Period in Patients with Unstable Angina[J];Journal of Liaoning University of Traditional Chinese Medicine;2010-04
8 LI Gui-sen,GAO Zhen (Yingkou City Central Hospital,Yingkou 115000,Liaoning,China);Step Naoxintong Capsule Combined with Intensive Lipid-lowering Therapy in Patients with Unstable Angina Clinical Observation[J];Journal of Liaoning University of Traditional Chinese Medicine;2010-04
9 LI Zong-xin, HUANG Xiao-bo, CHEN Wen-qiang, WANG Ning-qun. Department of Traditional Chinese Medicine, Xuanwu Hospital, the Capital Medical University, Beijing 100053, China;Discriminant analysis of carotid arteriosclerosis with traditional Chinese medicine syndromes[J];Chinese Journal of Cerebrovascular Diseases;2007-11
10 Qian Wenbin,et al (Hubei college of traditional Chinese medicine,Wuhan 430065);Preparation and Research into the Effects on the Decreace of the Hyperlipidemia of Mice of Water and Alcohol Extracts of Alisma Orientalis[J];Journal of Mathematical Medicine;2007-06
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 Yang Xiang-hua,Li Chun-jiang(Jiangsu Medical Traditional Chinese Medicine Treating Disease External Treatment Specialized Subject Hospital,Jiangyin 214404,China);Low Molecular Weight Heparin Combined with Simvastatin in The Treatment of Unstable Angina Pectoris Clinical Observation of 52 Cases[J];Chinese Journal of Medicinal Guide;2012-04
2 WANG Maojuan,YANG Xiaoqiong, DENG Shukai,WANG Rongli Department of Respiratory Diseases,the Affiliated Hospital, Luzhou Medical College,Luzhou 646000;Detection of matrix metalloproteinase-2, matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in serum and bronchoalveolar lavage fluid of community acquired pneumonia patients[J];Journal of Zhengzhou University(Medical Sciences);2010-06
3 WANG Hui-jiu Anyang People's Hospital,Anyang,Henan 455000,China;Serum of patients with coronary vascular endothelial growth factor and high sensitivity C reactive protein and clinical significance[J];Journal of Medical Forum;2011-01
4 CUI Changxiang1,KONG Lihong2,ZHOU Hongjuan3,YE Yiwan4,ZHOU Hua2 (1.Grade 2007 postgraduate student of Hubei University of Chinese Medicine,Wuhan 430061,Hubei;2.College of Acupuncture-Moxibustion & Orthopedics-Traumatology,Hubei University of Chinese Medicine,Wuhan 430061,Hubei;3.Shenzhen Luohu Traditional Chinese medicine hospital of Guangdong Province,Shenzhen 518001,Guangdong;4.Wuhan Hospital of Traditional Chinese Medicine,Wuhan 430014,Hubei);Effect of Acupoints Catgut Embedding Therapy on the Cortical VEGF mRNA Expression in Rats with Focal Cerebral Ischemia-Reperfusion Injury[J];Journal of Hubei University of Chinese Medicine;2010-04
5 YANG Rongmei,KONG Lihong,XU Xiaoshuang,WANG Yanggan(College of Acupuncture and Orthopedics,Hubei University of Chinese Medicine,Wuhan 430061);The Effect of Deformable Embedding Medicine in Acupoints on Brain Tissue MMP-9 of Rats with Focal Cerebral Ischemia Reperfusion Injury[J];Journal of Hubei University of Chinese Medicine;2012-02
6 XU XiaoShuang,KONG Lihong,YANG Rongmei,QIN Rong,LI Deping,WANG Yanggang(College of Acupuncture and Orthopedics,Hubei University of Chinese Medicine,Wuhan 430061);Effect of Deformable Embedding Medicine in Acupoints on Brain Tissue PCNA of Rats with Focal Cerebral Ischemia Reperfusion Injury[J];Journal of Hubei University of Chinese Medicine;2013-03
7 SUN Xing-zhen(Department of Pediatrics,Huai′an First Affiliated Hospital of Nanjing Medical University, Huai′an 223300,Jiangsu Province, China);Relationship between Serum C-Reaction Protein,Tumor Necrosis Factor-α and Changes of Myocardiac Enzymology,Coronary Artery Lesions in Children with Kawasaki Disease[J];Journal of Applied Clinical Pediatrics;2008-21
8 LIU Guo-yu1a,LIU Ge-li1a,YANG Qing-yan1a,MA Xian-cheng1a,MU Qing1a,ZHANG Yi1b,HU Tian-yi2(1a.Department of Pediatrics,General Hospital of Tianjin Medical University;1b.Department of Pediatrics,the Second Hospital of Tianjin Medical University,Tianjin 300070,China;2.Department of Pediatrics,Tianjin Public Security Hospital,Tianjin 300042,China);Diagnostic Value of Oral Glucose Tolerance Test for Metabolic Syndrome in Obese Children[J];Journal of Applied Clinical Pediatrics;2009-08
9 LIU Zhi-hui,MENG Qun,SHEN Ying(Department of Kidney Internal Medicine,Beijing Children′s Hospital Affiliated to Capital Medical University,Beijing 100045,China);Clinical Value of High-Sensitivity C-Reactive Protein in Children with Chronic Kidney Disease[J];Journal of Applied Clinical Pediatrics;2009-17
10 CHEN Feng,YAN Zhi-kang,YANG Bo(Department of Acu-moxibustion,People's Hospital of Wuhan University,Wuhan 430060,China);Effects of Acupoint-injection of Compound Angelica-root Injectio on Cerebral Bcl-2 and Bax Immunoactivity and Hemorheology in Rats with Cerebral Ischemia-reperfusion Injury[J];Acupuncture Research;2011-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved