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《Journal of Xinxiang Medical College》 2008-01
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Effect of puerarin for treatment of early patients with anterior ischemic optic neuropathy

LIU Ai-qin,LIU Xiang-ling,WAN Xin-shun,et al(Department of Ophthalmology,the Third Affiliated Hospital of Xinxiang Medical College,Xinxiang 453003,China)  
Objective To observe the clinical effect of puerarin in treatment of early patients with anterior ischemic optic neuropathy(AION).Methods 44 patients(44 eyes) were randomly divided into two groups(n=22).Patients in treatment group were intravenously performed with 200 mg puerarin plus 250 mL normal sodium once a day for 14 days,500 mL low molecule dextran were intravenously performed once a day for 14 days in control group.The sight and visual field were detected pre-and post-treatment in two groups.Results The effective rate in treatment group(95.45%) was obviously higher than this in control group(59.09%,P0.05).There were no significant difference in sight,average visual impairment and,sensitiveness before treatment between(P0.05).There were no significant difference in these indexes pre-and post-treatment in control group(P0.05),but there was significant difference in treatment group(P0.01),and there was significant difference of these indexes between two groups post-treatment(P0.05).Conclusion Puerarin can improve visual function in patients with early AION.
【CateGory Index】: R276.7
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