Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Xinxiang Medical University》 2013-05
Add to Favorite Get Latest Update

Toxic effects of Serrin B and Nodosin on HL60,SGC7901,LOVO,U87 and AGZY cells

HAI Guang-fan1,ZHANG Hui1,GUO Lan-qing2,BAI Su-ping1(1.Pharmacy College of Xinxiang Medical University,Xinxiang 453003,Henan Province,China;2.Nursing College of Xinxiang Medical University,Xinxiang 453003,Henan Province,China)  
Objective To study the toxic effects of Serrin B and Nodosin on human promyelocytic leukemia cell line HL60,human gastric adenocarcinoma cell line SGC7901,human colon carcinoma cell line LOVO,human glioma cell line U87 and human lung adenocarcinoma cell line AGZY in vitro.Methods The HL60,SGC7901,LOVO,U87 and AGZY cell lines in logarithmic phase were seeded in 96-well plates.When the cells adhere to the plates,different concentrations of Serrin B or Nodosin were added to the wells.The final concentrations were 0.00,1.25,2.50,5.00,10.00,20.00 μmol·L-1 respectively.24 hours later,four methyl thiazolyl tetrazobium methods were used to determine the death rates of the cells.Results There were obvious toxic effects for Serrin B on HL60,SGC7901,LOVO,U87 and AGZY cell lines in vitro(P0.01).The dose-effect relationship was obvious.There were significant toxic effects for Nodosin on HL60,SGC7901,LOVO,U87 cell lines(P0.05,P0.01).There was no toxic effect for Nodosin on AGZY cell lines.Conclusion Serrin B and Nodosin are the active anticancer components of Robdosia serra(Maxim) Hara,which offers more clues for the development of new anticancer drugs.
【Fund】: 河南省科技攻关计划项目(编号:122102310286)
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 6 Hits
1 YAO Yong-fang,LIAN Xiao-wei,ZHU Mei-juan,LUO Yi-zhu(Department of Food,Guangdong Industry Technical College,Guangzhou 510312);Study on bacteriostasis from Rabdosiea Serrae Hara and the effect of restraining bacteria[J];Food Science and Technology;2008-01
2 Li Zhen,Wu Hui,Lai Fu-rao(College of Light Industry and Food Science,South China University of Technology,Guangzhou 510640,China);Research on Antioxidant Activities of Polyphenol Extracted from Rabdosia serra(Maxim.) Hara[J];Food and Fermentation Industries;2012-06
3 BAI Su-ping, YANG Zhen-hua, FAN Bing-lin,et al (Department of Chemistry, Xinxiang Medical College, Xinxiang 453003, China);Studies on cytotoxicity of the diterpenoids from Isodon japonica[J];Journal of Xinxiang Medical College;2005-05
4 HAI Guang-fan,YAN Yan,LIU Ju-yuan,et al(Department of Pharmacology,Pharmacy College of XinXiang Medical College,Xinxiang 453003,China);Inhibitory Effects of enmein、serrin B、nodosin and lasiodonin on growth of HL60 cells and LOVO cells in vitro[J];Journal of Xinxiang Medical College;2008-06
5 ZHANG Qiao1,2,PAN Chao-mei3(1.Guangdong Vocational and Technical College of Pharmaceutical Chemistry,Guangzhou,510520,China; 2.Resource protection and use of South drugs Engineering Research and Development Center, Guangzhou,510520,China;3.Guangzhou University of Traditional Chinese Medicine,Guangzhou,510006,China);Different Morphology of Rabdosia serra Rabdosia lophanthoides Rabdosia lophanthoides var. gerardiana and Rabdosia lophanthoides var. graciliflora[J];Pharmacy Today;2012-01
6 HU Ying-jie, LAI Xiao-ping, LIU Zhong-qiu, ZHU Yu-tong, DENG Xue-long, LIU Ni, CHEN Jian-nan(Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, China);Chemical components of Isodon lophanthoides var. gerardianus and their anti-hepatitis B virus effects[J];Chinese Traditional and Herbal Drugs;2005-11
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 SHI Lin et al(Department of Food and Bioengineering,Guangdong Industry Technical College,Guangzhou,Guangdong 510300);Effect of Different Extraction Methods on the Chemical Constituents of Essential Oils from FOLIUM ARTEMISIAE ARGYI[J];Journal of Anhui Agricultural Sciences;2011-35
2 NI lin,LI Shu-hua,LU Hai-xiao,WEI Zhi-xiong,GAO You-heng(College of Traditional Chinese Medicine,Guangzhou University of Chinese Medicine,Guangzhou,Guangdong 510405,China);Determination of nodosin in Rabdosia nervosa by HPLC[J];Journal of Guangdong Pharmaceutical College;2010-06
3 HUANG Dong-lan,CHEN Xiao-kang*,XU Yong-qun,LI Gui-lian(School of Chemistry and Environmental Engineering, Shaoguan University,Shaoguan 512005,China);Determination of Trace Elements of Rabdosia Iophanthoides and Its Relative Species[J];The Journal of Light Scattering;2013-01
4 SHEN Xiao-hui;Academy of Agricultural Sciences in Jiamusi of Heilongjiang Province;;On Bacteriostasis of Orange Peel Extracts[J];Journal of Anhui Agricultural Sciences;2013-34
5 Xia Mengkai;Zeng Jing;Niu Chunli;Peng Fang;College of Pharmacy and Chemistry, Dali University;;Effect of Ganlong Capsule and Periplaneta americana Skimmed Cream on Bile Secretion of Normal Rats[J];Journal of Dali University;2015-02
6 HUANG Dong-lan;CHEN Xiao-kang;XU Yong-qun;School of Chemistry and Environmental Engineering ,Shaoguan University;;Identification of Four Original Species of Xihuangcao by 2D Infrared Correlation Spectroscopy[J];The Journal of Light Scattering;2015-01
7 LIANG Yu-Guang,HAO Guang-Tao,SU Jia,LIU Ze-Yuan*(Department of Pharmacology,Affiliated Hospital,Academy of Military Medical Sciences,Beijing 100071,China);Progress in research on diterpenoids from Isodon species(Labiatae) and their biological activities[J];Bulletin of the Academy of Military Medical Sciences;2009-02
8 SHI Lin*,YANG Yuan-e,YAO Yong-fang Department of Food and Bioengineering,Guangdong Industry Technical College,Guangzhou,Guangdong 510300,China;Effect of Different Extraction Methods on the Chemical Constituents of Essential Oils from FOLIUM ARTEMISIAE ARGYI[J];药用植物研究(英文版);2012-02
9 ZHAO Han-min,XU Hai-feng,LIANG Chao-ying(Department of Chemistry and Bioengineering Guangxi Normal Universities for Nationalities,Guangxi Chongzuo,532200);Test on the Polysaccharide Content of Rabdosia Serra(Maxim)[J];Journal of Guangxi Normal University for Nationalities;2011-03
10 LI Xiao-hui,ZHU Chen-hen,LI Chang-qing,et al.(1.School of Traditional Chinese Medicine,Guangzhou University of Traditional Chinese Medicine,Guangzhou 510405,Guangdong,P.R.China);Effects of extract of Isodon Lophanthoides var.gerardianus (Benth.) Hara on the production of TNF-α and the change of ultrastructure of liver cell in mice induced by concanavalin A[J];China Tropical Medicine;2011-11
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 YANG Bin1,LIU Xu-sen2,YUAN Quan-heng2(1The First People's Hospital of Guiyang City,Guiyang 550000,China;2The Affilited Hospital of Guiyang Medical College,Guiyang 550103,China);Mechanisms of inhibition on human pancreatic cancer PC-3 cell line by a diterpenoid compound 5 F isolated from Pteris semi pinnata L treatment[J];China Journal of Traditional Chinese Medicine and Pharmacy;2010-03
2 WANG Ya-dan;ZHANG Gui-jie;QU Jing;LI Yu-huan;JIANG Jian-dong;YU Shi-shan;State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking UnionMedical College;Institute of Medicinal Biotechnology,Chinese Academy of Medical Sciences and Peking UnionMedical College;;Study on the diterpenoids from Radix Illicii Maji and their antiviral activity against Coxsackie B virus[J];Journal of International Pharmaceutical Research;2013-06
3 HAO Lang-song,WANG Geng,QIAN Kun,LUO Ting,LI Xiao-jun,WU Xiao-ting~△.Department of General Surgery,West China Hospital,Sichuan University,Chengdu 610041,China;HIF-1α Expression and Relationship Involving Tumor Cell Proliferation and Angiogenesis in Human Breast Carcinoma[J];Journal of Sichuan University(Medical Science Edition);2007-01
4 TIAN Guang-hui,LIU Cun-fang,LAI Pu-hui (School of Chemistry, Shaanxi University of Technology, Hanzhong 723001, China);Study on Volatile Components of Essential Oil from Rabdosia nervosa Seeds and ItsA ntimicrobialA ctivities[J];Food Science;2008-02
5 Xin Qingfeng1,2,Chen Junhui2,Xie Xiaoyuan3,Shen Zhongying3 1The Third Affiliated Hosptal of Luohe Medical College,Henan Luohe 462000,China;2Peking University Shenzhen Hospital,Guangdong Shenzhen 518036,China;3Medical College,Shantou University,Guangdong Shantou 515031,China.;Morphological and functional changes of mitochondrial in apoptotic esophageal carcinoma cell induced by oridonin[J];Journal of Modern Oncology;2013-02
6 ZHANG Ji-xia,CHEN Zheng-yue,WANG Yong-xue,et al(Pharmaceutical Laboratory,Xinxiang Medical College,Xinxiang,Henan Province 453003,China);Chemical constituents of Isodon macrophylla[J];Journal of Xinxiang Medical College;2006-01
7 SHEN Yan1,L Bin1,ZHANG Shuo1,MA Zhong-jun2(1.Dept of Gastroenterology,the Frist Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310006,China;2.College of Pharmacy,ZhejiangUniversity,Hangzhou 310058,China);Apoptosis of human colon adenocarcinoma cell line SW620 induced by diterpenoid C from Radix Curcumae and its related pathways[J];Chinese Pharmacological Bulletin;2011-03
8 WANG Si-ming1,WANG Xi1,SU Xiao-hui1,ZHANG Man-li1,DONG Mei2,SHI Qing-wen1(1.Dept of Chemistry of Natural Products,School of Pharmaceutical Sciences, 2.Dept of Forensic Medicine,Hebei Medical Univercity,Shijiazhuang 050017,China);Inhibitory effect of lathyrane diterpen factors from Euphorbia lathyris on the proliferation of gynecologic cancer cells[J];Chinese Pharmacological Bulletin;2011-06
9 HE Jian-lin1,2,ZHENG Shi-zhong2,LU Yin2,XU Chang-an1,TANG Xu1,YI Rui-zao1(1.The Third Institute of Oceanography,State Oceanic Administration,Xiamen Fujian 361005,China; 2.College of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210029,China);Calcium channels in cancers[J];Chinese Pharmacological Bulletin;2012-07
10 CHEN Hui-li1,LI Jian-hua1,WANG Shu-qing2.(1.Weifang Medical College,Weifang 261041,China;2.Affiliated Hospital of Weifang Medical College,Weifang 261031,China);Correlative Study between Mitochondrial Transmembrane Potential and Apoptosis[J];Medical Recapitulate;2007-14
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 Ma Ligang;Zhao Le;Li Yingchao;Feng Weisheng;Kuang Haixue;Zheng Xiaoke;School of Pharmacy, Henan University of Traditional Chinese Medicine;Collaborative Innovation Center for Respiratory Disease Diagnosis And Treatment & Chinese Medicine Development of Henan Province;College of Pharmacy, Heilongjiang University of Chinese Medicine;;Cloning, Sequence Analysis and Prokaryotic Expression of GGPS Gene from Lepidium apetalum[J];Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology;2015-03
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 DU Jian;YANG Ying;ZHAO Ming-ye;WANG Jun;CHEN Min. College of Food Science and Nutritional Engineering,China Agricultural University,Beijing,100083,P.R.China.;Changes of antioxidant activity of phenolics in Toona sinensis during storage[J];Journal of Beijing Forestry University;2011-02
2 HUANG Li-hua1,ZHANG Ye-hui2,ZHAO Li-chao1,YOU Man-jie1,LIU Xin1 (1.College of Food Science,South China Agricultural University,Guangzhou 510642,China) (2.College of Light Industry and Food Sciences,South China University of Technology,Guangzhou 510640,China);Effects of Storage Condition on Apple Polyphenol Composition and Antioxidant Activity[J];Modern Food Science and Technology;2009-03
3 WEN Ling-rong, LIN Lian-zhu, ZHAO Mou-ming (College of Light Industry and Food, South China University of Technology, Guangzhou 510640,China);Compassion of Antioxidant Capacity of Extracts from Rabdosia Lophanthoides (Buch.Ham ex D.Don) Hara by Reflux Extraction and Decompression Reflux Extraction[J];Modern Food Science and Technology;2010-01
4 FU Ming, XIA Wei, LIU Sheng-gui, HU Chao-tun(Key Laboratory of Hunan Province for Study and Utilization of Ethnic Medicinal Plant Resources,Huaihua University;Key Laboratory of Hunan Higher Education for Hunan-western Medicinal Plant and Ethnobotany,Huaihua University;Department of Life Science,Huaihua University,Huaihua,Hunan 418008);Study on the Extraction and Anti-lipid Peroxidation Function of Chlorogenic Acid of Artemisia arborescens[J];Journal of Huaihua University;2011-05
5 DING Li-jun ZHOU Yan-fang LIN Nan (Chemical Department,Hanshan Normal University,Chaozhou,Guangdong 521041,China);Extracting of flavone from Rabdosiea Serrae Hara and its effects on scavenging of hydroxyl radicals[J];Food and Machinery;2004-03
6 Qian Jianya et al.;Study on Characteristics of Sweet Potato Purple Pisment[J];Food Science;2003-09
7 XU Ya-min1,2, ZHAO Xiao-yan2,*, MA Yue2, MENG Xian-jun1, LI Dong-hua1 (1.Shenyang Agricultural University, Shenyang 110161, Liaoning, China; 2.National Engineer Research Center for Vegetable, Beijing 100097, China);STUDY ON ANTIOXIDANT ACTIVITIES OF PURPLE CABBAGE PIGMENT[J];Food Research and Development;2006-11
8 LIANG Sheng-nian DUAN Zhi-fang FU Li (Department of Biology, Zhaoqing University, Zhaoqing, 526061);Antibacterial effect of the ethanol extract from Rabdosin serra(Maxim) Hara[J];Food Science and Technology;2003-12
9 Liu Xiaoqi Cao Enhua Zhu YuRong (Institute of Biophysics, Academia Sinica, Beijing 100101);A STUDY ON DNA DAMAGE INDUCED BY LIPID PEROXIDATION OF LINOLEIC ACID SYSTEM[J];Acta Biophysica Sinica;1993-03
10 LIU Yin-hua1,LIANG Li-qiu1,SHEN Jie1,AI Wen-li1,HU Zong-li2(1.Medical College of Shaoguan University,Shaoguan 512026,China;2.Biological Engineering College of Shaoguan University,Shaoguan 512005,China);Experimental Study on the Effect of Xihuangcao and Huzhang Decoctions on the Biliary Secretion in Wistar Rats[J];Lishizhen Medicine and Materia Medica Research;2009-07
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved