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《Chinese Journal of Information on TCM》 2004-04
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Clinical Research of the Bu Shen Sheng Sui Principle Curing the Postmenopausal Osteoporosis

LIAO Lin, LI Xue-song, CAI Quan-hui, et al (The People's Hospital of Zhongshan City, Zhongshan 528400, China)  
Objective To compare the curative effect of the Bu Shen Sheng Sui principle with the hormone replacement therapy, which were used to cure the postmenopausal osteoporosis. Methods 95 postmenopausal osteoporosis sufferers were divided randomly into three groups. The Chinese herbal medicine group (32 cases) takes Bu Shen Sheng Sui soup orally. The western medicine group (34 cases) takes the oral conjugated estrogen (1#/d) and medroxyprogesteronum (2.5 mg/d). And the control group (29 cases) do not make any special treatment. Half a year later, observe and give marks, regarding kidney deficiency syndrome as the main symptoms, and examine the serum hormone's level, blood calcium, blood phosphorus, liver kidney function and bone mass density (BMD). Then make a contrast with that before treatments. Results After the Chinese medicine and the western medicine's treatments, each main symptoms of the kidney deficiency syndrome can be alleviated availably. There was significant difference (P0.01). Besides, the serum estrogen and the progesterone will improve after curing. And a comparison between the two kinds of treatments shows that the two kinds remedies makes no different influence on the patients' estrogen and progesterone. The BMD of the entrance point of screw and the femoral have no variety. But regarding the two examinations in the control groups, the level of the BMD may report to a decline trend (P0.05). Conclusion Bu Shen Sheng Sui soup has the plant estrogen and progesterone kind function, it can raise the level of serum estrogen and progesterone hormone, so it may take the place of the estrogen and the progesterone. It can also avoid side effects such as the periodic vagina bleeds, mammary glandsache, etc. and averting the otiose panic in patients. Bu Shen Sheng Sui soup and hormone replacement can't improve the BMD effectively, but it can break the progress of the BMD's descent.
【Fund】: 广东省中山市科技计划项目(2001A061)
【CateGory Index】: R259
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