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《Chinese Journal of Information on Traditional Chinese Medicine》 2015-02
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Efficacy and Safety of Compound Kushen Injection Used for Peritoneal Perfusion on Patients with Malignant Ascites

LIU Jia-qi;Hubei Xinhua Hospital;  
Objective To observe the clinical efficacy and safety of compound Kushen Injection in the patients with malignant ascites. Methods Totally 139 patients with malignant ascites were randomly divided into treatment group and control group. 30 m L compound Kushen Injection was given to the treatment group, and 100 mg cisplatin was given to the control group through peritoneal perfusion once a week, for 3 weeks. The changes of urine volume, abdominal perimeter, blood-Rt, function of liver and kidney, and gastrointestinal reaction were detected before and after treatment, with a purpose to evaluate the total efficacy and safety. Results The total effective rate was 80.56%(58/72) in treatment group, and 86.57%(58/67) in the control group, without significant difference between the two groups. The incidences of bone marrow suppression, liver and kidney damage, and nausea and vomiting of gastrointestinal reaction were lower in the treatment group than the control group. Conclusion The effects of compound Kushen Injection and cisplatin have equal efficacy for the treatment of malignant ascites, but the former was superior to the latter on safety.
【CateGory Index】: R730.5
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2 CHENG Wei;GE Liang;MENG Xianjie;Shihezi People's Hospital;;Integrated Traditional Chinese and Western Medicine in the Treatment of Medium and Advanced Gastric Cancer:Report of 64 Cases[J];Clinical Medicine & Engineering;2014-04
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Yan, JIANG Ji kai*, LIU Xiao shan, et al Department of Clinical Biochemistry, Chongqing University of Medical Sciences, Chongqing 400016, P R China;Differentiation and apoptosis in K562 erythroleukemia cells induced by matrine[J];CHINESE JOURNAL OF CANCER;2000-08
2 HUA Hai-qing,JIANG Zi-yu,YANG Ai-zhen,QIN Shu-kui.Center of Oncology,Nanjing 81 Hospital of PLA,Nanjing 210002,China;The effect of Fufangkushen injection alone and the combined effect with oxaliplatin for antiproliferative and apoptotic action on human hepatoma cell line SMMC-7721[J];Chinese Clinical Oncology;2010-01
3 WANG Bing, WANG Guo jun,CAI Xiong,et al.Department of Medical Oncology,Shanghai Sixth People's Hospital,Shanghai 200233,China;Inhibitory Effect of Oxymatrine on Vascular Endothelial Cell Proliferation Induced by Hepatocellular Carcinoma Cell[J];Journal of Qilu Oncology;2003-07
4 YANG Qin,ZHANG Ya-shengDepartment of Traditional Chinese Medicine,the First People's Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200080,China.;Effects of matrine injection on expressions of mRNAs and proteins of VEGF and CXCR4 in gastric carcinoma SGC-7901 cells[J];Journal of Modern Oncology;2010-08
5 WANG Bing1,WANG Guo-jun2,XU Jun1(1.Department of Radiotherapy,Shanghai Sixth Hospital,Shanghai,200233,China; 2.Department of Infection,Changzheng Hospital,Second Military Medical University,Shanghai,200003,China);Inhibitory effect of Oxymatrine on vascular endothelial cell proliferation induced by tumor[J];JOURNAL OF PRACTICAL ONCOLOGY;2000-05
6 ZHANG Li-ming1,ZHENG Chuan-li2(1.Ningxia Medical College,Yinchuan 750021,China;2.Affiliated Hospital of Ningxia Medical College,Yinchuan,750004,China);Experimental Study on the Apoptosis of Osteosarcoma Cells Induced by Oxymatrine[J];Lishizhen Medicine and Materia Medica Research;2007-12
7 LI Min,QIAN Xiao-ping,LIU Bao-rui(Department of Medical Oncology,Gulou Hospital Affilicated to Medical College of Nanjing University,Nanjing,Jiangsu,210008);Experimental Study of Composite Radix Sophora Flavescentis Injection with Thermotherapy Inhibiting Angiogenesis[J];Journal of Clinical Medicine in Practice;2007-05
8 FENG Bai,ZHAO Xuequn(Dept.of Pharmacy,Tianjin First Central Hospital,Tianjin 300192,China);Effect of Composite Radix Sophora Flavescentis Injection on Immunological Function in Patients with Lung Cancer[J];China Pharmacy;2007-33
9 CHENG Xiangdong 1 ,DU Yian 1 ,HUANG Ling 1 ,JIANG Zhiming 2 ,ZHENG Zhiguo 21 Department of Hepatobiliary Surgery,Zhejiang Cancer Hospital,Hangzhou 310022,China 2 Zhejiang Cancer Institute,Hangzhou 310022,China;The Role of Matrine in Regulating the Expression of Bax and Bcl-2 in Hep G2 Cells Which Induce Apoptosis[J];Chinese Journal of Clinical Oncology;2008-12
10 ZHU Yan-qin,ZHOU Hui-ru (Department of Pathology,College of Basic Medical Sciences,Henan College of Traditional Chinese Medicine,Zhengzhou 450008);Study on Influence of Oxymatrine in Exosomatic Cell Antiproliferative Activity of Eca-109[J];Chinese Journal of Misdiagnostics;2008-08
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