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《Chinese Journal of Hemorheology》 2007-03
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The Clinical Study on Influence of the Epidural Anesthesia in Hypertensive during Perioperation

TANG Xian-ling,WANG Chun-yan,LI Zhu-hua(Dpartment of Anesthesia,the Afflitiated Hospital of Luzhou Medical College,Luzhou,Sichuan 646000)  
Objective To investigate the hemorheologic changes of hypertensive patients during epidural anesthesia.Methods 15 patients with systolic blood pressure(SBP)≥ 140mmHg and/or diastolic blood pressure(DBP)≥ 90mmHg,ASA classificationⅠ ̄ Ⅱ,who had underwent elective abdomen operation and had no other factors influencing hemorheology.They were received epidural anesthesia.Blood sample from all patients were taken at the following points:pre-anesthesia,30min after anesthesia,end-operation,24h,48h and 72h after operation.The blood samples were taken 5mL.each time from elbow vein and were tested for the hemoheological measure-ments within four hours in vitro.Blood viscosity(Hηb,Lηb,ηr,ηp)was determined at a shear rate of 200s-l and 3s-1 at 37℃ using an automatic rheological-examining machine,hematocrit(Hct) using capillary.Results 1.Before anesthesia,Hηb,Lηb and ηr;ηp,ESR were beyond normal range.2.There was not any change with all param-eters at 30min after anesthesia.By the end of operation,blood viscosities(ηb and ηp),ηr,ηp,EAI were descendant(P0.05)clearly and TK ascended clearly.3.At the 24h after end-operation we found all parameters were coming revive except ηp.The level of blood viscosity(ηb,ηp),EAI and ERI rose at 72h exceeding the preoperation appreciably.Conclusion The study suggest that epidural anesthesia is one of the useful method on hypertensive as it can meliorate the hemorheology of hypertensive.
【Fund】: 四川省教育厅重点资助课题(编号:2002A067)
【CateGory Index】: R614.42
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