Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Modern Medicine & Health》 2006-06
Add to Favorite Get Latest Update

Effects of resveratrol on behavior and memory senility caused by D-galactose in rats

ZHANG Min1,ZHOU De-lan2,CHEN Yong-Xin2 (1. Department of Microbiology,Guangdong Medical College,Zhanjiang 524023,China;2. Guangxi Medical University,Nanning 530021,China)  
Objective:This study was designed to investigate whether there was influence on behavior and memory senility caused by D-galactose in rats which were injected with resveratrol in a certain dose. Methods:One hundred mice were randomly divided into 5 groups according to injection condition(normal saline,D-galactose,low,middle and high dose of resveratrol). The D-galactose group and resveratrol group were continually injected with D-galactose for 72 days. And the resveratrol group was continually injected with resveratrol from the 23th day to the 72th day. After these animal models were finished,they were undergone these tests including Y type maze step through test. Morris maze test and lipofuscin guantitative analysis. Results:There was no statistical difference between low dose of resveratrol and models. Such differences of swimming length and the mumbers through the flat roof in Morris maze and the right numbers in Y type maze through test and the brain lipofuscin content were statistically valid by spss analysis between the D-galactose group and the middle and high dose of resveratrol group(P0.05),but there was no statistical difference between middle and high dose of resveratrol groups. Conclusion:The middle and high dose of resveratrol can improve the behavior and memory senility caused by D-galactose,and can inhibit the development of the brain lipofuscin.
【CateGory Index】: R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 3 Hits
1 CHEN Luo-xi,GUO Ling-ling,LI Liang(Chendu University of Traditional Chinese Medicine,Chengdu 610075,Sichuan,China);Application of Rounded Morris Water Maze and Analysis of Correlated Indicatrix[J];Journal of Liaoning University of Traditional Chinese Medicine;2008-08
2 ZHENG Xiao-xia,HUANG Hong-na,ZHANG Dan-shen,XUE Gui-ping.(The Pharmacological Department,Hebei North University,Zhangjiakou 075029,China);Research Progress in Neuroprotective Function of Resveratrol[J];Medical Recapitulate;2009-20
3 CUI Xin-ying,LI Xiang-yan(Pharmacy College of Beihua University,Jilin 132013,China);Effect of Prunus cerasus L Juices on Learning and Memory in Senile Mice Induced by D-Galactose[J];Journal of Beihua University(Natural Science);2009-06
Chinese Journal Full-text Database 3 Hits
1 ZHAO Ya-li, PENG Xiao-dong, YANG Yu-hua, MA Hong-bo, SONG Jin-ping, PU Jing-suiInstitute of Space Medio-Engineering, Beijing 100094,China;Effects of 2 450 MHz Microwave on Long-term Potentiation of Hippocampus and Lipofuscin Contents in Rat Brain.[J];Space Medicine & Medical Engineering;2004-02
2 LI Wen-Bin;WEI Fen;FAN Ming;ZHANG Jin-Li;ZNANG Bing-Lie;MA Xian-Chen;YANG Wei-Ping;WEI Wen(Institute of Gerontology ane Geriatries, General Hospitalof People's Liberalion Army, Beijing,100853);Mimetic brain aging effect induced by D-galactose in mice[J];CHINESE JOURNAL OF PHARMACOLOGY AND TOXICOLOGY;1995-02
3 Yu Jing, Ren Zhaoyang, Cang Jing(Life Science College, Northsaeast Agricultural University, Harbin Heilongjiang 150030);A Promising Secondary Metabolite-Resveratrol[J];Chinese Agricultural Science Bulletin;2005-07
Chinese Journal Full-text Database 10 Hits
1 XIE Xue-yuan,WANG Qiang(Department of Pharmacy,Naval General Hospital,Beijing 100037,China);A study on anti-aging action of Potentilla anserina Lextract[J];Chongqing Medicine;2007-08
2 ZHAN Peng-fei, ZHANG Yan, ZHU Xiang-rui (College of Animal Sciences, Zhejiang University, Hangzhou 310029, China);Extraction and Determination of Resveratrol from Different Parts of Mulberry[J];Bulletin of Sericulture;2008-04
3 LIU Xian-ming,LI Yue-fen,LI Guo-ping(Department of Neurosurgery,Municipal Hospital of Qingdao,Qingdao 266071,China);Anti-aging effects of theanine on aging model mice induced by D-galactose[J];Journal of Traumatic Surgery;2008-03
4 ZHU Xiang-Rui1 FEI Jian-Ming2 YANG Yi-Wen3 YANG Kun1(1College of Animal Sciences,Zhejiang University,Hangzhou 310029,China;2Huzhou Academy of Agricultural Science,Huzhou Zhejiang 313000,China;3Anji Chaolong Sericultural Development Company,Anji Zhejiang 313300,China);Preliminary Investigation on Resveratrol Content in Mulberry Pericarp and Branch[J];Science of Sericulture;2007-01
5 XU Yu-fen~1,YE Bing-ying~1,CHEN You-qiang~(1,2*),WANG Bing-mei~1,HUANG Qing-huang~1,LIN Zhi-kai,CHEN Ru-kai~2(1.College of Life Sciencies,Fujian Normal University,Fuzhou 350108,China;2.Key Lab of Eco-physiology & Genetics Improvement of Sugarcane,Ministry of Agriculture,Fuzhou 350108,China);Construction of the Monocotyledon Expression Vector for the Transforming of Resveratrol Synthase Gene[J];Journal of Fujian Normal University(Natural Science Edition);2007-01
6 SUN Bo,ZHOU Hongying,LI Yong, WU Hui (Industrial Crops Institute, Hubei Academy Of Agricultural Sciences, Wuhan 430064,China);Study Progress in Mulberry Fruit Ingredients[J];North Sericulture;2010-01
7 KANG Yanfang1,LI Mengqing1,HOU Jiangong2,JU Yinxuan1,LIU Guimin1,LIU Songqin3(1 Department of Pharmaceutical Engineering,School of Chemical Engineering,Hebei University of Technology,Tianjin 300130,China;2Hebei Veryong Bio-chemical Co.,Ltd,Shijiazhuang 050031,Hebei,China;3 Chemical Equipment Limited Company of Shijiazhuang University of Technology,Shijiazhuang 050031,Hebei,China);Ultrasonic extraction of resveratrol from waste residue of grape spike-stalk[J];Chemical Industry and Engineering Progress;2006-11
8 Tangwei (department of biochemistry, Yunyang medical college, Hubei, Shiyan, 442000);Effect of Chinese yam polysaccharides on MDA of mice[J];Journal of Huanggang Polytechnic;2002-01
9 Tang Wei Zhu Minglei Song Minghua (Demartment of biochemistry, Yunyang medical college, Hubei, Shiyan, 442000);Experimental Studies on the Effect of Chinese Yam Plysaccharides on Anti - Aging of Mice[J];Journal of Huanggang Polytechnic;2002-03
10 LI Chu-hua 1, LIU Mei-lian 1, ZHENG Yan 2, DONG Chuan-hong 1, XIAO Peng 1 (Department of Biology, South China Normal University,Guangzhou 510631, China);INHIBITION OF LEARNING AND MEMORY INDUCED BY D-GALACTOSE IN MICE AND RATS[J];Journal of South China Normal University(Natural Science);2001-04
Chinese Journal Full-text Database 10 Hits
1 ZHANG Wei~1,ZHANG Yu~ 1,ZHAO Qing~2,YANG Yong-mei~1 (1. Department of Neurology, First Hospital, Jilin University, Changchun 130021, China; 2. Department of Neurology, China-Japan Union Hospital, Jilin University, Changchun 130031, China);Effects of β-amyloid on learning-memory and hippocampus neuron ultrastructures in aging rats induced by D-galactose[J];Journal of Jilin University of (Medicine Edition);2005-02
2 BO Tao~(1△),CHEN Yong~2,MAO Ding-an~1,LI Yan-fang~1,ZHU Xiao-hua~1 (1.Department of Pediatrics,the Second Xiangya Hospital,Central Southern University,Changsha 410011,China;2.Department of Neurology,Jiangxi Children Hospital);Long-term effects of neonatal recurrent seizures on γ-aminobutyric acid A receptor α1 and γ2 subunit expressions in the rat brain[J];Journal of Peking University(Health Sciences);2006-06
3 WANG Lin, FU Xian-ming, QIAN Ruo-bing, NIU Chao-shi, LU Ming. Department of Neurosurgery, Affiliated Provincial Hospital, Anhui Medical University, Hefei 230001, China;Changes of ethology and brain morphology in morphine-addicted rats[J];Chinese Journal of Neuromedicine;2006-12
4 ZHOU Jie,LEI Peng,ZHANG Xiang,et al.(Department of Neurosurgery,Lanzhou General Hospital,Lanzhou Command,Lanzhou 730050,China);Effect of resveratrol on the neural apoptosis of impaired brain tissue in rats with head injury[J];Journal of Traumatic Surgery;2008-01
5 ZHANG Jian-Dong, HOU Yi-Ping, SONG Yan-Feng, ZHANG Lang, WANG De-Gui Department of Anatomy, Basic Medical College, Lanzhou Medical University, Lanzhou 730000, China;Intake of phosphatidylcholine from soybean lecithin improves learning and memory ability and hippocampal synaptophysin expression in young rats[J];Journal of The Fourth Military Medical University;2005-09
6 YUAN De-pei,LI Jun,WANG Ping(Medical College,Hubei Institute for Nationalities, Enshi 445000,China);Effects of “Bushen Huoxue Huatan Prescription” on Space Learning Memory and Expression of nNOS in Hippocampus Region of Rat Model with Alzheimer's Disease[J];Journal of Hubei Institute For Nationalities Medical Edition;2004-04
7 FAN Xiao\|lan, WANG Wei, ZHAO Xiao\|zhen (Division of Anatomy, Histology and Embryology, Fujian Medical University, Fuzhou\ 350004, China) \ \;Effect of Sex and Age on the Morris Water Maze Memory Performance of Rats[J];Journal of Fujian Medical University;2003-01
8 Zhou Guoxing, Wang Chunxu, Liu Zhengqin. Chinese Medicine and Drug College of Hunan,Changsha 410013 China;The pretreatment of heat stress influences the memory and learning of mice[J];Anatomy Research;2004-04
9 Pan Ya,Zeng Zhaoyi,Lu Xinrui,et al.Guiyang Medical College,Guiyang 550004;The effect of Insulin on the Capabilities of Learning Memory and the Expression of Aβ_(1-40) in Hippocampal CA1 Region of AD-like rats[J];Guizhou Medical Journal;2006-08
10 LUO Li, HUANG Yi-ming~ (Deparment of Nutrition and Food Hygiene, School of Public Health, Central South University, Changsha 410078,China);Effect of resveratrol on the cognitive ability of Alzheimer’s mice[J];Journal of Central South University(Medical Sciences);2006-04
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 XIE Ri-qing,TAO Tao,CHEN Min-li,ZHU Ke-yan,PAN Yong-ming,ZHOU Wei-min,LENG Xiao-xia,XIAO Hui,AI Xiu-feng,YU Jia(Zhejiang Chinese Medical University Laboratory Animal Research Center,Hangzhou 310053,China);Research on Learning Memory Ability and Behavior of Ageing Model Rat Induced by D-galactose and Interventional Effect of Traditional Chinese Medicine[J];Chinese Journal of Comparative Medicine;2010-05
2 LIU Bin1 ,MAO Wen-jing1,LI Ai-chuen1,MA Yuan-yuan1,ZHANG Jin-xia1,LI Shi-ying,LI Jian-min2 ( The Affiliated Hospital of North China Coal Medical College,Tangshan 063000,China);Effect of Shenxiong Huayu Capsule on Expression of p38MAPK in CA1 Area of Hippocampus in Vascular Dementia Rats[J];Chinese Journal of Experimental Traditional Medical Formulae;2010-08
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved