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《Journal of Modern Medicine & Health》 2013-01
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Experimental study of semen astragali complanati extracts on blood glucose in mice

Deng Xiaoying,Yao Limei,Xie Xiaoxia,Zhang Qiao,Zhuang Yixiu(Guangdong Food and Drug Vocational College,Guangzhou,Guangdong 510520,China)  
Objective To observe the influence of semen astragali complanati extracts on blood glucose in normal and streptozotocin(STZ)-inducing diabetes mellitus(DM) mice.Methods Semen astragali complanati extracts were given to nomal mice once daily for consecutive 10 d by oral administration and to DM mice model induced by STZ for 20 d by peritoneal injection.The animal status was observed.Blood was collected for separating serum and detecting the fasting blood-glucose levels before and after drug administration.Results Various extracts of semen astragali complanati had no obvious influence on blood glucose in normal mice,while high-dose of semen astragali complanati extract B could reduce blood glucose significantly in STZ mice(P0.05).Conclusion Semen astragali complanati extract B can reduce the levels of fasting blood-glucose in DM animal models and has certain curative effect on DM animal models.
【CateGory Index】: R285.5
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