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《New Medicine》 2013-12
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A follow-up study of poststroke aphasiarecovery using acupuncture and donepezfil

LI Ai-ping;XIAO Wei-min;WANG Yu-ming;XIONG Xiao-ping;HUANG Xiao-qiong;Department of Neurology,Dongguan People's Hospital of Guangdong Province;  
Objective To evaluate the effectiveness of combining acupuncture and donepezfil in patients with post-Infarction aphasia. Methods One hundred and twenty patients with acute aphasic infarct were randomly assigned into 4 groups: standard speech-language therapy group( group A),donepezil( 5 mg / d) as an adjunctive treatment to standard speech-language therapy group( group B),acupuncture as an adjunctive treatment to standard speech-language therapy group( group C) and a combination of donepezil( 5 mg / d), acupuncture and standard speech-language therapy group( group D). All patients underwent clinical assessment( western aphasia battery) three times over a 24-week period( the 1st,12th,and 24thweeks) and clinical scores were analyzed. Results Compared with the baseline in each group,all items of WAB scores and Aphasia Quotien( AQ) were statistically significant( all P 0. 05). The difference in all items of WAB scores and AQ between different groups in the 12thand 24thweek became statistically significant. The significant improvement rate in the combination of donepezil,acupuncture and standard speech-language therapy group was 77% which was significantly greater than that of other groups( group A 27. 6%,group B 50% and group C 46%,all P 0. 05). Conclusion Acupuncture combined with donepezil has been shown to improve the poststroke aphasia.
【Key Words】: Acupuncture Donepezil Poststroke aphasia
【Fund】: 东莞市医疗卫生科技计划一般项目(201110515001082)
【CateGory Index】: R246.6;R743.33
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