Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of New Drugs and Clinical Remedies》 2003-11
Add to Favorite Get Latest Update

Pharmaceutical effects of total glucosides of peony and its application in autoimmune disease

ZHOU Qiang,LI Zhan guo (Department of Rheumatology and Immunology, People's Hospital, Peking University, Beijing 100044, China)  
It was found that total glucosides of paeony (TGP) had inhibitive effects on autoimmune response via variant pathway. It also had effects of inflammation suppressing, analgesia, and hepatic protecting. It had precisely therapeutic effect on autoimmune diseases, such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). This presenting review has summarized the studies of TGP on cellular, humoral immunity, anti inflammation, and clinical studies on auto immune diseases.
【CateGory Index】: R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 10 Hits
1 SHAO Fu-rong,WEI Wei,LIU Hao,SUN Wu-yi,LI Xiang(Institute of Clinical Pharmacology of Anhui Medical University, Anhui Hefei 230032,China);Comparison of Protective Effect of Shaoqiduogan Extracted by Different Methods on Immunological Liver Injury in Mice[J];Journal of Anhui Traditional Chinese Medical College;2007-05
2 SHI Peng Department of Nephrology, PLA 451 Hospital, Xi'an 710054, China;Effects of total glucosides of paeony on active Heymann nephritis in rats[J];Journal of The Fourth Military Medical University;2005-18
3 REN Feng-lian,QU Bai-lu and TAN Xiao-yan(College of Chemistry and Chemical Engineering,Central South University,Changsha 410083);Determination of total glucoside content of paeony in Paeonia lactifloria Pall.by Alkaline hydrolysis-UV spectrophotometry[J];Chinese Journal of Analysis Laboratory;2008-10
4 JIANG Xing-lin1,JIANG Le-long1,HU Xiang-shang1,WANG Yu-ai1,TIAN Xiao-ying1,DENG Wei-feng1,FANG Hua2,LIU Hui2(1.Department of Laboratory Medicine,Huaihua Medical College,Huaihua Hunan 418000;2.Dalian Medical Universty);Probe into the Influence to Mouse Body Fluid Immunologic Function by TCM Paeonia Lactifiora Pallas[J];Journal of Huaihua Medical College;2006-02
5 YU Hui-min,NIE Ying-kun,WANG Jing-lu(Department of Traditional Chinese Medicine,The Second Clinical College,Harbin Medical University,Harbin 150081,China);Effects of total glucosides of paeonia on the serum levels of NO and IL-1β in patients with knee osteoarthritis[J];Journal of Harbin Medical University;2007-05
6 SHANG Shu,GU Jin-jin,TANG Guo-yao.Shanghai 9th People's Hospital Affiliated to Medical College,Shanghai Jiaotong University.Shanghai 200011,China.;The clinical evaluation of total glucosides of paeony on treating oral lichen planus[J];Journal of Clinical Stomatology;2007-04
7 WU Hao,LI Wei,GE Hong-mei,LIU Ping*(Department of Oncology,the First Affiliated Hospital of NJMU,Nanjing 210029,China);Paeoniflorin induces the apoptosis of human gastric carcinoma cells by inhibiting activation of NF-κB[J];Acta Universitatis Medicinalis Nanjing(Natural Science);2008-02
8 WANG Wenjun, WANG Peixun, LIANG Ruiyan(Institute of Immunology, Guangzhou University of TCM, Guangzhou 510405, China);Studies on In-Vitro Biological Activity of Albiflorin R1 in Counteracting Cell Proliferation[J];Journal of Guangzhou University of Traditional Chinese Medicine;2005-01
9 GUO Hui1,ZHANG Ling2(1.School of Pharmaceutical Sciences,Shandong University,Jinan 250012 China;2.Institute of Biopharmaceuticals of Shandong Province,Jinan 250108,China);Progress on Traditional Chinese Medicine Curing Rheumatoid Arthritis[J];Food and Drug;2007-01
10 QU Bai-lu1,2, WU Hong-yi2,3, REN Feng-lian2, YU Wen-feng1,2, WANG Ji-zhang2 (1.Changsha Environmental Monitoring Station, Changsha 410001; 2.College of Chemistry and Chemical Engineering, Central South University, Changsha 410083; 3.Institute of chemical Defence, Beijing 102205);Analysis of essential oil composition of Paeionia lactiflora Pall.by GC/MS[J];Food Science and Technology;2009-03
China Proceedings of conference Full-text Database 1 Hits
1 CHEN Gang,GUO Li-Xia,DENG Xiao-Hong,YIN Zhong-Yi,JING Jia-Jia (Research Center of Medical Chemistry and Chemical Biology,Chongqing Technology and Business University,Chongqing 400067,China);Effects and mechanism of total glucosides of paeony on nitric oxide and inducible nitric oxide synthase production in macrophages[A];[C];2010
【Citations】
Chinese Journal Full-text Database 10 Hits
1 Gao Benbo; Dai Liming; Xu Shuyun(Institute of Natural Drugs 261042);THE SCAVENGING ACTIVITIES OF TGM AND TGP ON FREE RADICALS[J];JOURNAL OF WEIFANG MEDICAL COLLEGE;1996-01
2 Wei Wei, Liang Junshan Zhou Aaiwu et al (The clinical Pharmacology Institute, Anhui Medical University, Hefei );EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ON INTER-LEUKI'N 2 PRODUCTION[J];Chinese Pharmacological Bulletin;1989-03
3 Liang Junshan, Wei Wei & Zhou Aiwu (The Institute of Clinic Pharmacology, Anhui Mecical University, Hefei 230032);METHOD FOR MEASURING IL-1 AND EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ( TGP ) ON IL-1 PRODUCTION[J];Chinese Pharmacological Bulletin;1989-06
4 Wang Xingwang1, Wei Wei, Chen Mingzhu, Xu Shuyun ( Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032 );MECHANISM OF IMMUNOMODULATORY ACTIONS OF TOTAL GLUCOSIDES OF PAEONY IN MICE[J];Chinese Pharmacological Bulletin;1990-06
5 Li Jun, Zhao Weizhong1, Chen Minzhu , Xu Shuyun (Dept. of Phas., Institute of Clinical Pharmacology1, Anhui Medical University, Hefei 230032);EFFECT OF TOTAL GLUCOSIDES OF PAEONY ON LEUKOTRIENE B_4 BY PERITONEAL MACROPHAGES IN RATS[J];Chinese Pharmacological Bulletin;1992-01
6 WANG Xing-Wang, CHEN Ming-Zhu. XU Shu -Yun (Institute of Clinical Pharmacology . Anhui Medical Unirersity . Hefei 230032);The effects of total glucosides of paeony (TGP) on T lymphocyte subsets[J];Chinese Pharmacological Bulletin;1992-05
7 DAI Li-Ming, CHEN Xue-Guang, XU Shu-Yun (Dept Of Pharmacology, Anhui Medical University, Hefei, 230032);Protective effects of total glucosides of paeony on experimental hepatitis[J];Chinese Pharmacological Bulletin;1993-06
8 WANG Zhi-Jian; CHEN Ming-Zhu; SUN Gut-Hua; XU Shu-Yun(Anhui Medical University, Hefei 230032);Effect of total glucoside of paeony on rheumatoid arthris patients[J];CHINESE PHARMACOLOGICAL BULLETIN;1994-02
9 LI Jun; CHEN Min-Zhu; XU Shu-Yun (Inst,of Clinical Pharmacology,Anhui Medical University,hefei 230032);Effect of total glucosides of paeony on prostaglandin E_2 derived from peritoneal macrophapes and its sectional mechanism in rats[J];CHINESE PHARMACOLOGICAL BULLETIN;1994-04
10 WANG Bin, CHEN Min Zhu, XU Shu Yun (Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032);Regulatory mechanism of total glucosides of paeony on tumor necrosis factor production by peritoneal macrophages in rats[J];CHINESE PHARMACOLOGICAL BULLETIN;1997-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Li Xiaomei,Li Xiangpei,Wang Guosheng,et alDepartment of Rheumatology,Anhui Provincial Hospital,Hefei 230001;Effectiveness and safety of total glucosides of peony in the treatment of patients with Sjogren syndrome[J];;2006-05
2 LI Jun, ZHANG Yun-Fang, TANG Xiao-Lin, LI Chang-Yu, XU Shu-Yun (Institute of clinical pharmacology, Anhui medical University, Hefei 230032);Therapeutic effects of nimesulide on adjuvant arthritis in rats[J];Anhui Medical and Pharmaceutical Journal;1997-03
3 ZANG Yin-shan (Dept of Rheumatology, People's Hospital of Pizhou,Jiangsu 221300,China);Observation on curative effects of total glucosides of paeony for juvenile idiopathic arthritis[J];Anhui Medical and Pharmaceutical Journal;2005-02
4 WANG Shi-hong~(1,2),WEI Wei~(1),XU Du-juan~(1),XU Shu-ping~(1),CUI Ying~(2)(1.Institute of Clinical Pharmacology,Anhui Medical University;Anhui Key Laboratory of Antiinflammatory and Immunopharmacology;Anhui Provincial Key Laboratory of R&D of Chinese Medicine,Hefei 230032;2.He'nan College of TCM,Zhengzhou 450008);Proliferation inhibition of TGP on SMMC-7721 Cell in vitro[J];Anhui Medical and Pharmaceutical Journal;2006-01
5 CHEN Xiang qing,WANG qin mao,FANG Hua wu,SU Cui mei (Dept. Of Pharmacy, Anhui Provincial Hospital,Anhui Hefei 230001,China);PROTECTIVE EFFECTS OF TOTAL GLUCOSIDES OF PAEONY AND EXTRACT FROM ANGELICA SINENSIS ON EXPERIMENTAL HEPATITIS[J];Journal of Anhui Traditional Chinese Medical College;2002-03
6 Anhui Technical Teachers College Fengyang 233100) LIU Han\|zhen 1\ LIU Ai\|rong 1\ LI Xiao\|liang 1\ LI yi\|song 2\;2 Anhui angriculture college Hefei 230031\;;The Chemical Composition and Pharmacodynamics Resersh Recent Development about Peeled Root of Herbaceous Penoy[J];Journal of Anhui Agrotechnical;2001-04
7 Wang Yuwei,Wang Yongjun Zhejiang Chinese Medical University Hangzhou(310053);Pharmacological Study and Clinical Application of Total Glucosides of Peony in Autoimmune Diseases[J];Journal of Zhejiang University of Traditional Chinese Medicine;2007-02
8 CHEN Xiang-qing,WANG Qin-mao,FANG Hua-wu,et al (Dept.Of Pharmacy,Anhui Provinical Hospital,Anhui Hefei 230001,China);PROTECTIVE EFFECTS OF TOTAL GLUCOSIDES OF PAEONY AND EXTCACT FROM ANGELICA SINENSIS ON EXPERIMENTAL IMMUNOLOGICAL LIVER INJURY[J];Journal of Chengde Medical College;2004-01
9 WANG Dong feng 1,3 ,LI Jun 2,WANG Chang hong 1, ZHAO Gui wen 3 JIN Yong 2,CHENG Ding ding 1,YE Sheng 1 [WT6BX](1 Key Laboratory of Tea Biotechnology,Anhui Agricultural University,Agricultural Ministry of the Peoples Republic of China,;Study on the Component and Immune Activity of Polysaccharides from Tea[J];JOURNAL OF TEA SCIENCE;2000-01
10 SHI Peng Department of Nephrology, PLA 451 Hospital, Xi'an 710054, China;Effects of total glucosides of paeony on active Heymann nephritis in rats[J];Journal of The Fourth Military Medical University;2005-18
China Proceedings of conference Full-text Database 1 Hits
1 LIANG Yuanyuan, ZHU Chenchen(New Drug Research& Development Center, Guangzhou University of TCM, Guangzhou, 510405);Determination of Paeoniflorin in Gujing Pill by HPLC[A];[C];2004
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 DENG Chao et al(School of Medicine and Pharmaceutics,Jiangnan University,Wuxi,Jiangsu 214122);Effects of Collagen Peptide from Cyanea nozakii on Mice Immune Function[J];Journal of Anhui Agricultural Sciences;2009-08
2 REN Feng-lian,QU Bai-lu and TAN Xiao-yan(College of Chemistry and Chemical Engineering,Central South University,Changsha 410083);Determination of total glucoside content of paeony in Paeonia lactifloria Pall.by Alkaline hydrolysis-UV spectrophotometry[J];Chinese Journal of Analysis Laboratory;2008-10
3 SUN Lili WANG Lei GUO Libing pharmacy college in Guangdong Pharmacy College Guangdong Guangzhou 510006;Developments in RA Treated by the Traditional Chinese drug[J];International Medicine & Health Guidance News;2007-08
4 ZHANG Ying1,KANG Yuan-yuan1,DING Xian-wu1,MENG Wen2(1.Department of Comprehensive Emergency,Affiliated Stomatology Hospital,China Medical University,Shenyang,110002,China;2.Hospital of Traditional Chinese Medicine of Shenhe District,Shenyang,110013,China);Clinical effect of compound chamomile and lidocaine hydrochloride gell and dexamethasone in the treatment of oral lichen planus[J];The Chinese Journal of Clinical Pharmacology;2008-02
5 LIU Xian-xiang,LI Ming-bo,CHEN Wen-lie,et al(Fujian Academy of Integrative Medicine,FUTCM,Fuzhou,Fujian 350108,China);Effects of Tougu Xiaotong Granule on Differentiation of BMSCs into Chondrocytes[J];Journal of Fujian University of Traditional Chinese Medicine;2009-04
6 SONG Jian-wu1,CHAO Zhi2,DONG Wei-ren1( 1Department of Histology and Embryology,College of Basic Medicine,2School of Traditional Chinese Medicine,Southern Medical University,Guangzhou 510515,China);Synthesis of huperzine A-bovine serum albumin conjugate and its immunogenicity in mice[J];Acta Academiae Medicinae Militaris Tertiae;2009-21
7 ZHANG Yuan-chao,SUN Hong-sheng,PAN Zheng-lun,LI Ming (Department of Rheumatology and Immunology,Shandong Provincial Hospital,Shandong University,Jinan 250021,China);Research progress of total glucoside of paeony in rheumatic disease[J];World Clinical Drugs;2010-08
8 CHAI Yi-feng*,ZHU Zhen-yu and CHEN Xiao-fei(Department of Pharmaceutical Analysis,School of Pharmacy,Second Military Medical University,Shanghai 200433),Fenxi Shiyanshi,2010,29(9):78~122;Pharmaceutical analysis(I)[J];Chinese Journal of Analysis Laboratory;2010-09
9 GUAN Xiao-bing,BAI Jing-ping,ZHANG Hui-na,WANG Li-hua,LI Ping,SUN Zheng.Department of Periodontology,Capital Medical University School of Stomatology,Beijing 100050,China;Clinical evaluation of Yangyin Yiqi mixture in the treatment of oral lichen planus[J];Beijing Journal of Stomatology;2010-04
10 Guo Cuiping Zhumadian second Chinese Medicine Hospital ,Henan,Zhumadian 463000;Treatment of irritable bowel syndrome by Lipi Decoction for 34 cases[J];Guangming Journal of Chinese Medicine;2010-11
China Proceedings of conference Full-text Database 5 Hits
1 XU Jin-sen SHAO You-yan LIN Ji-yun CAI Bi-shuang ZHANG Lei-qiong (School of Life Sciences,Key Laboratory of Ministry of Education for Cell Biology and Tumor Cell Engineering,Xiamen University,Xiamen 361005,PR China);UV Spectrophotometric and MALDI-TOF-MS Determinations of Hapten Number for the Artificial Paeoniflorin -HSA Conjugates[A];[C];2007
2 SONG Jian-wu~1,CHAO Zhi~(2*),DONG Wei-ren~1,TANAKA Hiroyuki~3 (1.College of Basic Medicine,Southern Medical University,Guangzhou 510515,China;2.School of Traditional Chinese Medicine,Southern Medical University,Guangzhou 510515,China;3.Graduate School of Pharmaceutical Sciences,Kyushu University,Fukuoka 812-8582,Japan);Identification and immunogenicity analysis of a conjugate of huperzine A with bovine serum albumin[A];[C];2008
3 Zhengyu Zhang~1 Yuanhong Zhao~2 Jie Yu~1 1.Tianjin University of Traditional Chinese Medicine 2007 Graduate 2.Oncology Department 2.The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine;Tumor metastasis to the offensive and defensive references[A];[C];2009
4 YE Tianshen,FANG LI~2,WENXIA XIE,YONG CHEN,RUIXIAN ZHENG,YUEFEN WANG,CHI ZHANG~1 (The first Affiliated Hospital of Wenzhou medical college,Wenzhou325000,China;2enrolled postgraduates,Wenzhou medical college,Wenzhou325000,China);Clinical Research of abdominal acupuncture combined with Tripterygium wilfordii ~7in the Treatment of Post-menopause women with Active Rheumatoid Arthritis[A];[C];2009
5 LIU Jun 1、2,ZHANG Jian-jun 2 (1. Guangzhou University of Chinese Medicine,Guangzhou 510405,China; 2.Guangdong Provincial Institute of Traditional Chinese Medicine,Guangzhou 510095,China);Optimization of the Processing Parameters for the Extraction of Total Glucoside of Paeony in Paeony Dispensing Granule using Box-Behnken experimental design[A];[C];2010
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Wei Wenshu,Wang Youqi& Wang Yushan et al ( The Clinical Pharmacology Institute of Anhui Medical University, Hefei );IMMUNOREGULATORY EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ROOT IN MICE[J];Chinese Pharmacological Bulletin;1987-03
2 Liang Junshan, Chen Minzhu and Xu Shuyun ( Clinic Pharmacoloy Institute, Anhui Medical University, Hefei);EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ON CHEMILUMINESCENCE OF PERITONEAL MACROPHAGES IN RATS[J];Chinese Pharmacological Bulletin;1988-04
3 Wang Yongxiang ,Wang Weiqun & Huang Jiping et al (Dept. of Phar., Anhui Medical University , Hefei);THE PROTECTIVE EFFECT OF TGPs ON ACUTE LIVER INJURY INDUCED BY CARBON TETRACHLORIDE IN MICE[J];Chinese Pharmacological Bulletin;1988-06
4 Wei Wei, Liang Junshan Zhou Aaiwu et al (The clinical Pharmacology Institute, Anhui Medical University, Hefei );EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ON INTER-LEUKI'N 2 PRODUCTION[J];Chinese Pharmacological Bulletin;1989-03
5 Liang Junshan, Wei Wei & Zhou Aiwu (The Institute of Clinic Pharmacology, Anhui Mecical University, Hefei 230032);METHOD FOR MEASURING IL-1 AND EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ( TGP ) ON IL-1 PRODUCTION[J];Chinese Pharmacological Bulletin;1989-06
6 Zheng Yiwen, Ma Donglai, Chen Minzhu (The Clinical Pharmacology Institute, Anhui Medical University, Hefei 230032);EFFECTS OF LUTEOLIN ON H_2O_2 RELEASE OF PERITONEAL MACROPHAGES IN RAT[J];Chinese Pharmacological Bulletin;1990-01
7 Guan Yongyuan, Duan Dayue, Wu Jiexioag, Sun JiaJun ( Dept. of Phar, Sun Yat sen University of Medical Sciences, Guangzhou 510089) Kwan CY (Dept. of Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada L8N 3Z5 );DETERMINING EFFECTS OF CARDIOTOXIN FROM SOUTHERN CHINESE COBRAVENOM ON THE CYTOPLASMIC CALCIUM ION CONCENTRATION OF LACRIMAL ACINAR CELLS ISOLATED FROM RAT WITH FURA-2 FLUORESCENCE TECHNIQUE[J];Chinese Pharmacological Bulletin;1990-05
8 Wang Xingwang1, Wei Wei, Chen Mingzhu, Xu Shuyun ( Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032 );MECHANISM OF IMMUNOMODULATORY ACTIONS OF TOTAL GLUCOSIDES OF PAEONY IN MICE[J];Chinese Pharmacological Bulletin;1990-06
9 Li Jun, Zhao Weizhong1, Chen Minzhu , Xu Shuyun (Dept. of Phas., Institute of Clinical Pharmacology1, Anhui Medical University, Hefei 230032);EFFECT OF TOTAL GLUCOSIDES OF PAEONY ON LEUKOTRIENE B_4 BY PERITONEAL MACROPHAGES IN RATS[J];Chinese Pharmacological Bulletin;1992-01
10 WANG Bin; CHEN Min-Zhu; XU Shu-Yun(Institute of Clinical Pharmacology,Anhui medical University,Hefei 230032);Effect of total glucosides of paeony (TGP) on tumor necrosis factor produced by peritoneal macrophages in rats[J];CHINESE PHARMACOLOGICAL BULLETIN;1995-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved