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Lipid Peroxidation Effect of Sodium Fluoride in Vitro, and Inhibition Effects of Some Antioxide Agents

Yang Zhenzhong  
Addition of sodium fluoride (NaF) in various concentration to the rat liver homogenate elicited a significant increase of lipid peroxides, and showed a rather good dose-response relationship. Concentration of NaF up to 1.25mg/ml hepatic homogenate was considered to be optimed to produce maximed amount of lipid peroxides, since higher concentration of the former could lead to decrease of the content of the latter. Antioxides like vitamin C, vitamin E and 2-mereaptoethanol inhibited markedly the lipid peroxidation effect of NaF.
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