Experimental study on the photo-protection of Baikal skullcap root of human skin cells from ultraviolet radiation damage
MIN Wei, LUO Dan, LIN Xiang-fei (Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China)
Objective To evaluate the photo-protective efficiency of Baikal skullcap root, a traditional Chinese medicine, on human skin cells (keratinocytes and fibroblasts), from UV radiation damage. Methods Subconfluent keratinocytes and fibroblasts were shammed or irradiated with different doses of UVB and UVA and treated with Baikal skullcap root agents. The vitality of cells was determined by MTT method. Results The intervention of Baikal skullcap root could preserve the cellular vitality by 8%～38%. Conclusion The UV radiation injury to human skin cells (keratinocytes and fibroblasts) can be reduced by Baikal skullcap root.