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《Chinese Pharmacological Bulletin》 1986-04
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ANTIINFLAMMATORY, ANTIPYRETIC AND ANALGESIC EFFECTS OF SUDOXICAM

Jia Xiurong, Jiao Wencai, Wei Wenshu, Chen Mingzhu & Xu Shuyun ( Institute of Clinical Pharmacology, Anhui Medical University )  
This paper describes the anti-inflammatory, antipyretic and analgesic effects of Sudoxicam ( Sud) synthesized by Shenyang Pharmaceutic College.Sud is found to possess significant anti-inflammatory, antipyretic and analgesic quality in such animal models as carrayeenan-induced paw oedema ( ED50=5.26mg/kg ) , tylolinduced ear oedema in mice, adjuvant-induced arthritis in rats, yeast-induced fever in rats, acetic acid-induced arithing ( ED50= 5.0mg/kg ) and hot plate-induced pain reaction in mice.
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