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《Chinese Pharmacological Bulletin》 1987-06
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Chen Jue & Xu Hengjun (Department of Pharmacology, Institute of Materia Medica Zbejiang Academy 玣 Medicine, Hangzhoti)  
The influence of Gynostemma pentaphyllum extract ( G. P ) on the life span of fruit fly was observed. G. P (0.5% and 1.0%) significantly increased mean life span by 11.8% and 12.2%, respectiyely, when fed to male adults. At 0.25% concentraction, the female adults were found to yield an increase of 24.1% in mean life span and the male an increase of 18.5%. Rearing flics on 0. 5% G. P during both the developmental and adult stages proved to be even more effective than just feeding during the adult stage. The mean life span of male and female adults were increased by 53.3% and 46.1% , respectively, but at the higher concen- tration of 1.0%, the increase was 14.4% and 9.7%, respectively, G. P obviously improved the growth of larvae when given a concentration of 0.5%, No marked change was observed in the copulatory rate of fruit flies after the treatment of 0.5% G.P.
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