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《Chinese Pharmacological Bulletin》 1992-02
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EFFECTS OF SUPERNATANTS FROM CULTURED RAT PINEAL GLANDS ON THE FUNCTIONS OF LYMPHOCYTES

Wei Wei, Liang Junshan, Chen Xueguang et al ( Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, )  
Effects of supernatants from cultured rat pineal glands on ConA and LPS induced proliferative responses of splenocytes in mice, ConA induced interleukin 2 (IL-2) production of splenocytes in rats were studied. These results showed that ConA and LPS induced proliferative responses of splenocytes were enhanced by supernatants from cultured rat pineal glands stimulated with 10 μmol/L isoproterenol (ISO) for 60 min (Dilution. 1 : 45 ) , ConA induced IL-2 production of splenocytes in rats was also enhanced by the supernatants (Dilution: 1 : 135 ) .
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