Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《CHINESE PHARMACOLOGICAL BULLETIN》 2000-01
Add to Favorite Get Latest Update

Effect of ganoderma polysacchrides on PKC activity in murine peritoneal macrophages

LI MingChun, LEI LinSheng1, LIANG DongSheng, XU ZiMing, YANG ShuQin1, SUN LiSha1 (Dept of Pharmacy, 401 Hospital of PLA, Qingdao 266071)  
AIM To investigate the effect of Ganoderma polysacchride(GLB 7) on PKC activity in murine peritoneal macrophages METHODS A new ionpair reversedphase high liquid chromatography method was used to determinate the activity of protein kinase C in cellsRESULTS GLB 7 (40 mg·L -1 )induced activation,translocation of PKC, and GLB 7 antagonized the inhibition effect to PKC of staurosporine(10 μmol·L -1 ) in murine peritoneal macrophages The peak time was 30 minutes,the activity of PKC came back the basic level at 2 hours CONCLUSION The immunopoteniating effect of Ganderma polysacchride may be associated with its activation of PKC in murine peritoneal macrophages
【Fund】: 国家自然科学基金资助项目!No39400165
【CateGory Index】: R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 10 Hits
1 LI Wan-kun1,2,YAN Hong-bin1,CAI Xue-peng1,GUO Fu-cun2,3(1.National Key Lab of Livestock Pathogenic Biology,Key Lab of Gansu Vet.Parasitic Diseases,Lanzhou Institute of Vet.Medicine CAAS,Lanzhou 730046,China;2.College of Vet.Medicine,Gansu Agri.University,Lanzhou 730060,China;3.Alltech Biological Product(China) Co.,Ltd,Beijing 101407,China);Mechanism Study of β-glucans for Enhanced Immune Competence[J];China Animal Husbandry & Veterinary Medicine;2007-07
2 GAO Shi-Yong,ZHANG Yu-Jin, WANG Shuai-Shuai, ZOU Xiang(Postdoctoral Programme, Institute of Materia Medica, Harbin University of Commerce, Harbin 150076,China);Study on red cellular immunity and sialic acid content of Xianlu Kang'ai capsule[J];Journal of Harbin University of Commerce(Sciences Edition);2005-04
3 WANG Dao Fu ①,SHAO Lin Ping ②,JU Bao Wen ③,YUAN Yao Ming,DING Wang ( ①Dept of Pharmacy,89 Hospital of PLA,Weifang 261000,Shandong) ( ②People's Hospital of Weifang City,Weifang 261021,Shandong) ( ③Weifang City Institute for Drug Contro;Effect of Auricularia Polytricha Sacc Polysaccharide on PKC Activity in Murine Peritoneal Macrophages[J];Pharmaceutical Journal of Chinese People's Liberation Army;2002-01
4 WANG Bin,KAYAGAKI Noboru,LI Jie-fen(Department of Diagnostics of Traditional Chinese Medicine,Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405,China);Effects of Ganoderma polysaccharides on proliferation of dendritic cells in mouse spleen[J];Immunological Journal;2006-03
5 ZHAO Kun~1,LI Jing-xi~1,ZHANG Hui-hui~1,GUO Dong-sheng~1,JIA Bei-bei~1,WANG San-hu~1,ZHANG Shi-jun~2(1.Henan Institute of Science and Technology,Xinxiang 453003 China;2.Institute of Biology,Henan Academy of Science,Zhengzhou 450008,China);Studies on the Effect of Alfalfa Polysaccharide on the Immune Efficacy of Swine Fever Vaccine[J];Journal of Henan Agricultural University;2005-04
6 YU Hong-tao1,2,WU Mao-yu1,ZHAO Yan1,HU Xiao-song3,XIAO Li-xia2,(1.Jinan Fruit Research Institute All China Federation of Supply & Marketing Co-operatives,Jinan 250014,Shandong,China;2.College of Tourism and Cuisine,College of Food Science and Engineering,Yangzhou University,Yangzhou 225002,Jiangsu,China;3.China Agricultural University,Beijing 100083,China);Progress on the Studies of Extraction and Physiological Activity of Polysaccharides from Ganoderma Lucidum[J];Food Research and Development;2011-05
7 HE Chuan-bo1, LI Lin2, TANG Feng-xia1, XIONG He-jian1 (1.School of Bioengineering, Jimei University, Xiamen 361021; 2.School of Light Chemistry and Food Science, South China University of Technology, Guangzhou 510640);Isolation and immunological activities of polysaccharide from Morinda officinalis how[J];Food Science and Technology;2009-08
8 ZHANG Lei;BAO Bin;LIU Jian;School of Biotechnology and Food Engineering,Hefei University of Technology;Hefei Fengle Seed Co.Ltd.;;Luteolin Inhibits Obesity-Associated Adipose Tissue Macrophage Polarization through Protein Kinase C(PKC) Pathway[J];Food Science;2014-13
9 XU Jing-juan WU Min-chen ZHU Jie CHEN Ping(School of Medicine and Pharmaceutics,Jiangnan University,Wuxi 214122,China);Study on Immunoregulatory Function of Agrocybe cylindracea Polysaccharide(ACP)[J];Journal of Food Science and Biotechnology;2007-06
10 LI Ming-Chun; LEI Lin-Sheng;WANG Qing-Biao; LIANG-Sheng; XU Zi-Ming; YANG Shu-Qin; SUN Li-Sha (Dept of Pharmacy,401 Hospital of PLA, Qngdao 266071) (Dept of Pharmacology, the First Military University, Guangzhou 510515);Effect of Ganoderma polysacchride on intracellular free calcium and intracellular pH in murine T cells[J];Chinese Pharmacological Bulletin;2001-02
【Citations】
Chinese Journal Full-text Database 3 Hits
1 School of Pharmaceutical Sciences He Yunqing, Li Rongzhi, et al;STUDIES OF ACTIVE POLYSACCHARIDES OF GANODERMA LUCIDUM[J];;1989-03
2 Lin Zhibin Department of Pharmacology;IMMUNOPHARMACOLOGIC RESEARCHES OF GANODERMA POLYSACCHARIDES AND ITS SIGNIFICANCES[J];;1992-04
3 Li Mingchun, Liang Dongsheng, Xu Ziming, Yuan Jinhua (Navy 401 Hospilal (Qingdao 266071);Determination of Protein Kinase Activity by Ion-pair RT-HPLC[J];CHINESE JOURNAL OF BIOCHEMICAL PHARMACEUTICS;1999-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 SONG Li et al(College of Food Science and Engineering,Northwest A & F University,Yangling,Shaanxi 712100);Advances in Analysis Methods of the Structure of Ganoderma lucidum Polysaccharide[J];Journal of Anhui Agricultural Sciences;2012-10
2 Lin Zhibin Department of Pharmacology;IMMUNOPHARMACOLOGIC RESEARCHES OF GANODERMA POLYSACCHARIDES AND ITS SIGNIFICANCES[J];;1992-04
3 He Yunqing School of Pharmacy Sciences;STUDIES ON ACTIVE POLYSACCHARIDES GLA FROM GANODERMA WITH ANTI-AGING ACTIVITY[J];;1992-06
4 ZHANG Qun-Hao; LIN Zhi-Bin (Department of Pharmacology, Beijing Medical University. Beijing 100083);Effect of Ganoderma lucidum polysaccharides B on TNFα and IFNγ preduction and their mRNA expression[J];Journal of Beijing Medical University;1999-02
5 LIN Zhi-Bin △ (Department of Pharmacology,Peking University School of Basic Medical Sciences,B eijing 100083,China);Progress of studies on the anti-tumor activity and immunomodulating effect of Ganoderma[J];Journal of Beijing Medical University;2002-05
6 WAN Ping,TANG Kaihui(School of Bioindustry,Chengdu University,Chengdu 610106,China);Preliminary Exploration on Cultivating Conditions of Deep Submerged Fermentation for Ganoderma Liquid[J];Journal of Chengdu University(Natural Science Edition);2009-04
7 NIU Jun fang,FANG Zheng,WANG Hong geng,WANG Guo chao (Key Laboratary of Bioinorganic Chemistry of Hebei, Bioinorganic Chemistry Laboratory, Agricultural University of Hebei, Baoding 071001, China);The research advance on the effective constituents of Ganoderma spp.[J];Journal of Agricultural University of Hebei;2002-S1
8 SHANG De jing 1, WANG Guan lin2, WANG Xiao min2, TIAN Xing2, AN Yue2 ( 1. School of Chem. Eng., Dalian Univ. of Technol., Dalian 116012, China; 2. Liaoning Normal Univ., Dalian 116029,China );Isolation, purification and property identification of two kinds of polysaccharide containing selenium in Ganoderma lucidum[J];Journal of Dalian University of Technology;2001-02
9 ZHOU Jing-hua(Faculty of Basic Medicine,Dali University,Dali,Yunnan 671000,China);Research and Clinical Application Prospects of Polysaccharides[J];;2006-06
10 Lei Linsheng ; Sun Lisha; Yang Shuqin(Department of Pharmacology, First Military Medical Universlty, Guangzhou, 510515);Effect of interaction of Ganoderma polysaccharides with concanavalin A on proliferation of mouse splenocytes in vitro[J];Journal of First Military Medical University;1998-04
China Proceedings of conference Full-text Database 2 Hits
1 YU Yong-Nian (Systematic Mycology & Lichenology Laboratory, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080) SHEN Ming-Zhu (Institute of Agricultural Environment & Sustained Development, Chinese Academy of Agricultural Science, Beijing 100081);THE HISTORY OF LINGZHI [GANODERMA SPP.] CULTIVATION[A];[C];2003
2 Chen Jianwei Yan Songbai and Jiang Yaping The Institute Center of Medicinal Fungi & Bio-technology of Traditional Chinese Medicine, Nanjing 210029;The Development and Applying of the Polysaccharide Resources of Medicinal Fungi in China[A];[C];2005
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 CHEN Guan min, LIN Sheng qing, HUANG Zong xiu, CHEN Ren xiong, HE Ling, JIANG Rui chai (Fujian Provincial Health and Anti epiodemic Station, Fuzhou 350001, China);STUDY ON THE ANTIMUTAGENICITY OF LENTINAN[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;2000-02
2 DENG Li xia\+1, Hu Bin\+1, CHEN Xiao jun\+2, CHEN Tie jiang\+1, GUN De xiu\+1, ZHENG Lü kong\+1, FAN Rui quan\+1(1. Department of Toxicology, School of Public Health, Zhong shan University; 2. Tumor Research Institute, Zhong shan University, Guang;STUDY OF THE GERMINATION ACTIVATED GANODERMA SPORES ON TERATOGENICITY, MUTAGENICITY AND ANTIMUTAGENICITY[J];Carcinogenesis,Teratogenesis and Mutagenesis;2002-03
3 CHANG Si-si1,MA Zhi-min1,,SONG Zheng-rui1,LIU Guang-ming2 (1.School of Public Health,Dali University,Dali 671000;2.School of Pharmacy,Dali University,Dali 671000,China);The anti-mutation effect of extracts from pinecones[J];Carcinogenesis,Teratogenesis & Mutagenesis;2010-01
4 WANG Zi-ying(Department of Biology,Anhui Institute of Education,Hefei,230061,China);The Comparison of ISSR and PAPD Analysis of Edible Wild Mushrooms of Anhui[J];Journal of Anhui Institute of Education;2005-06
5 Xu Shouming et al.(Institute of Agricultural Biotechnology,college of life science,Henan University,KaiFeing 475004,China);Study on Apoptosis and Cytochrome C[J];Anhui Agricultural Science Bulletin;2009-15
6 WANG Lei et al (College of Life Sciences,Ludong University,Yantai,Shandong 264025);Study on Phylogenetic Relationship of Cultivated Strains of Coprinus comatus[J];Journal of Anhui Agricultural Sciences;2006-16
7 TAO Da-yong (College of Animal Science and Technology,Tarim University,Alar,Xinjiang 843300);Immunomodulation Effect of Lycium barbarum Polysaccharide[J];Journal of Anhui Agricultural Sciences;2007-22
8 HUANG Sheng-quan et al(College of Light Industry and Food Sciences,South China University of Technology,Guangzhou,Guangdong 510640);Study on Extraction Technology of Water-soluble Polysaccharide from Ganoderma lucidum by Ultrasonic Assistant Method[J];Journal of Anhui Agricultural Sciences;2009-23
9 ZHANG Zhen et al (College of Pharmacy,Dali University,Dali,Yunnan 671000);Studies on Chemical Constituents from Pinus armandii Franch[J];Journal of Anhui Agricultural Sciences;2010-24
10 Zhang Buchang et al (Biology Dept,Anhui University,Hefei, 230039 );Study on extraction, purification and blood - sugar lowering of a polysaccharide from danpi (root shin of Paeonia suffruticasa Andr. )[J];JOURNAL OF ANHUI AGRICULTURAL SCIENCES;1995-04
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 CAI Ai-qun (Yingdong College of Bioengineering,Shaoguan University,Shaoguan,Guangdong 512005);Wild Edible Fungi Resources of Antitumor in the North Region of Guangdong Province[J];Journal of Anhui Agricultural Sciences;2008-01
2 HU Shun et al(Food Science and Technology Institute of Hunan Agricultural University,Changsha,Hunan 410128);Progress in Research on Ganoderma lucidum Spore Oil[J];Journal of Anhui Agricultural Sciences;2010-17
3 SHEN Cong-wei et al(Celluar and Molecular Lab of Chinese Materia Medica,Sichuan Academy of Chinese Medicine Sciences,Chengdu,Sichuan 610066);Research Progress on Pharmacological Activities of Auricularia polytricha Polyaccharide[J];Journal of Anhui Agricultural Sciences;2011-22
4 WANG Yan-hua,WANG Cheng-zhang,SHI Ying-hua,LI Zhen-tian,CHEN Ji-hong,PAN Jun-liang(Engineering College of Animal Husbandry and Veterinary Science,Henan Agricultural University,Zhengzhou 450002,China);The research progress on alfalfa polysaccharides[J];Pratacultural Science;2007-04
5 FAN Wen-na,WANG Cheng-zhang,SHI Peng-fei,YAN Xue-bing,XU Bing,YANG Ling-ling(College of Animal Science and Medicine,Henan Agricultural University,Zhengzhou 450002,China);Progress situation on research and application of alfalfa in animal diet[J];Pratacultural Science;2009-01
6 SHI Ying-hua,WANG Cheng-zhang,CHEN Ming-liang,YAO Hui-xia,YUAN De-di,WANG Xian-ke(College of Animal Science and Veterinary Medicine,Henan Agricultural University,Henan Zhengzhou 450002,China);Effects of alfalfa hay meal on growth performance,antioxidant and immune values of Sichuan white geese[J];Pratacultural Science;2011-05
7 LIU Yanyan,QIN Guang,LI Jichang(College of Veterinary Medicine,Northeast Agricultural University,Harbin 150030,China);Regulating effect on immunologic function and cytokine by PHA compound preparation in chicken[J];Journal of Northeast Agricultural University;2011-06
8 TAO Hao1,WEI Bingdong2,CHEN Qun2(1.College of Animal Technology,Jilin Agricultural University,Changchun 130118,China;2.Branch Institute of Animal Husbandry,Jilin Academy of Agricultural Sciences,Gongzhuling Jilin 136100,China);Effect of astragalus polysaccharide on mucosal structure in small intestine of 14-day-old broilers[J];Journal of Northeast Agricultural University;2012-03
9 DONG Xiao-fang1 JIANG Yong1 GAO Wei-wei2 SA Ren-na1 ZHANG Qi1 TONG Jian-ming1(1.State Key Laboratory of Animal Nutrition,Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing 100094,China;2.Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences;Beijing 100094,China);Effect of Polysavone on some Parameters of Immunity,Incretion and Lipid Metabolism in Broiler Chickens[J];Chinese Journal of Animal Nutrition;2007-04
10 CHEN Qing-hua LIU Zhu-ying HE Jian-hua(College of Animal Science and Technology,Hunan Agriculture University,Changsha 410128,China);Effects of Achyranthes Bidentate Polysaccharide on the Proliferation of Lymphocytes and Concentrations of Cytokine in Peripheral Blood Mononuclear Cells of Piglets[J];Chinese Journal of Animal Nutrition;2008-06
China Proceedings of conference Full-text Database 6 Hits
1 Shan Jun-jie,Jiang Wei,Zhu Ting,Wang Yu-xia (1.Institue of Pharmacology and Toxicology,Academy of Medical Sciences,Beijing,100850,China);Application of Polysaccharides on Vaccine Adjuvant[A];[C];2011
2 ZHANG Yan~(1,2),GAO Shi-yong~(1,2),JI Yu-bin~(1,2) (1.Postdoctoral Programme of Institute of Materia Medica,Life Sciences and Environmental Sciences Research Center,Harbin University of Commerce,Harbin 150076,China;2.MOE Engineering Research Center of Natural Anticancer Drugs,Harbin University of Commerce, Harbin 150076,China);Advances on effect of structural modification of polysaccharides against anti-tumor activities[A];[C];2011
3 ;Research of the Fingerprint Methods of Ganoderma lucidum and Application of Cluster Analysis[A];[C];2007
4 XIE Dian, CHEN Yao-xing, WANG Zi-xu, LI Jun-ying, CAO Jing, JIA Liu-jun (College of Animal Medicine, China Agricultural University, Beijing 100094; College of Animal Science, China Agricultural University, Beijing 100094);Effects of Monochromatic Light on Immune Function in the Splenoctye of Broilers[A];[C];2006
5 TIAN Li-xin,JIN Xiao,SHI Bin-lin,ZHANG Cai-fen,CUI Yu-ming,LI Hui-ying,GUO Xiao-yu(College ofAnimal Science,Inner MongoliaAgricultural University,Hohhot 010018,China);Effects of Chitosan on Intestinal Microecology in Broilers[A];[C];2012
6 CHEN Liangyan, XIE Jia, Cao Yang, CHEN Zhong College of Life Sciences, Hainan Norm al University, Haikou, China, 571158;Research Advances on the Extraction Methods of Morinda officinalis How Polysaccharides and Its Biological Functions[A];[C];2012
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Gong Zheng Lin Zhi-bin Department of Pharmacology, Beijing Medical College;THE PHARMACOLOGICAL STUDY OF LINGZHI (GANODERMA LUCIDUM) AND THE RESEACH OF THERAPEUTICAL PRINCIPLE OF "FUZHENG GUBEN" IN TRADITIONAL CHINES EMEDICINE[J];;1981-01
2 Guan Hong-chang, Cong Zheng Department of Pharmacology, Beijing Medical College;EFFECTS OF LINGZHI POLYSACCHARIDE D_6 ON THE BIOSYNTHESIS OF NUCLEIC ACIDS AND PROTEIN[J];;1981-04
3 WAN Qian;CHEN Chang-Zheng;TU Hong-Min;LI Bao-Liang and XIA Qi-Chang(Shanghai Institute of Biochemistry,Academia 200031);A New Assay for Protein Kinase A Using Capillary Electrophoresis[J];ACTA BIOCHIMICA ET BIOPHYSICA SINICA;1995-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved