Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Pharmacological Bulletin》 2007-01
Add to Favorite Get Latest Update

DNA topoisomerase and antitumor

MO Xiao-mei, LI Jing, GENG Mei-yu (Molecular Pharmacology Lab, Medicine College, Ocean University of China,Qingdao Shandong 266003,China)[FL(2K2]  
DNA topoisomerase is a basic enzyme in eucaryon and prokaryotic cells, which distributes in cell nucleus generally. DNA topoisomerase plays important roles in the process of duplication, transcription, translation, recombination and chromosome monomer isolation to control, keep and modify the DNA topology. It is reported that DNA topoisomerase has a high expression level, which related with the mechanism of many antitumor drugs.
【Fund】: 国家重点基础研究发展规划(973规划)资助项目(No2003CB716400)
【CateGory Index】: R730.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 8 Hits
1 ZHANG Yan-li1,YANG Yi-dong1,LI Zu-qiang2,FANG Tian-tian1,LIU Ya-min1,QING Chen1(1.The Key Laboratory of Pharmacology for Natural Products in Yunnan Province Kunming Medical College,Kunming 650031,China;2.Research Center,School of Chemistry and Material Engineering,Yunnan University,Kunming 650091,China);Antitumor activity of santamarin and its effect on topoisomerase[J];Chinese Pharmacological Bulletin;2007-10
2 GAO Shi-yong,JI Yu-bin(Postdoctoral Research Station,Institute of Materia Medica,Life Science and Environment Science ResearchCenter of Harbin Commerce University,Harbin 150076,China);Research advance of arylamine N-acetyltransferase[J];Chinese Pharmacological Bulletin;2008-01
3 ZHANG Jia-jie,WANG Guang-fa,WU Shu-guang(School of Pharmaceutical Sciences,Southern Medical University,Guangzhou 510515,China);Interactions of anticancer drugs and miRNA targets[J];Chinese Pharmacological Bulletin;2008-11
4 TAN Hui-xin(Pharmacy Department of the Forth Affiliated Hospital to Harbin Medical University,Harbin 150001,China);Research progress on topoisomerase Ⅰ inhibitors[J];Chinese Pharmacological Bulletin;2009-04
5 ZHOU Qing-feng1,LI Ming-yue2,NA Guang-shui3,LI Cheng-wei1(1.Dept of Life Science and Technology,Shangqiu Normal College,Shangqiu Henan 476000,China;2.School of Life Science and Technology,China Pharmaceutical University,Nanjing 210009,China;3.National Marine Environmental Monitoring Center,Dalian Liaoning 116023,China);Progress in research of antitumor mechanisms of marine polysaccharides[J];Chinese Pharmacological Bulletin;2009-08
6 MA Yun-tong (Editorial board,Xi'an University of Arts and Science,Xi'an 710065,China);DNA Damage,Repair and Checkpoint Response Mediated by Topoisomerase Ⅰ Inhibitor[J];Journal of Xi'an University of Arts & Science(Natural Science Edition);2010-01
7 LI Yan-mei1,2,SHEN Xiao-yan1 (1. Laboratory of Pharmacology and Toxicology,School of Pharmaceutical Sciences, Sun Yat-Sen University,Guangzhou 510275,China;2. Bio-Pharmacy Technology of R & D Center,Institutes of Life & Health Engineering,Jinan University,Guangzhou 510632,China);Progress in the study of G-quadruplex telomerase inhibitors[J];Chinese Pharmacological Bulletin;2010-01
8 LU Li,PENG Fang. ( College of Pharmacy,Dali Universi- ty,Dali 671000,China);Advances in Targeted Anti-tumor Drugs[J];Medical Recapitulate;2010-13
【Citations】
Chinese Journal Full-text Database 1 Hits
1 LIU Ming-hua1,QING Chen1,LIU Ji-kai2,ZHANG Yan-li1, Wang Lei1, JI Shu-yu1 (1.The Key Laboratory of Pharmacology for Natural Products in Yunnan Province , Kunming 650031,China; 2.The State Key Laboratory of Phytochemistry and Plant Resources in West of Chin a; Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204,China );Study on the antitumor activity of Albaconol and its effect on DNA topoisomera se Ⅱ[J];Chinese Pharmacological Bulletin;2004-11
【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 CONG Yue1,GUO Jinggong2,WANG Tianxiao1,LI Mian1,LI Ke1,WANG Jinhui3,LI Qin 1(1.Institute of Traditional Chinese Materia Medica,School of Pharmacy,Henan University,Kaifeng 475004,China;2.Key Laboratory of Plant Stress Biology,Henan University,Kaifeng 475004,China;3.School of Taditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,China);Chemical constituents and antitumor activity on leukemia K562 cell of Leonurus heterophyllus[J];China Journal of Chinese Materia Medica;2009-14
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 JIANG Chao, QING Chen, MENG Ling hua, et al. Shanghai Institute of Material Medical,Chinese Academy of Sciences,Shanghai 200031,P.R.China;Inhibitory effects of China ganoderma lucid essence (CGLE) on DNA topoisomerases and its ability to induce apoptosis of K562 cells[J];CHINESE JOURNAL OF CANCER;1999-06
2 CHEN Ling ji, HAN Jia xian, YANG Wei yi, LU Li juan, ZHANG Jia liu,YANG Qiu long, YUAN Sheng tao, DING Jian*Division of Anti Tumor Pharmacology,State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 200031,P.R.China;Inhibition of Mixture of Lucid Garoderma and Lucid GarodermaSpore on Tumor Cell In Vitro and In Vivo[J];Chinese Journal of Cancer;2002-12
3 PENG LING,YU ZHUANG,SONG YANG(Department of Oncology,The Affiliated Hospital of Qingdao University Medical College,Qingdao 266003,China);EFFECT OF STICHOPUS JAPONICUS ACIDIC MUCOPOLYSACCHARIDE ON PROLIFERATION AND DIFFERENTIATION OF Hela CELLS[J];Acta Academiae Medicinae Qingdao Universitatis;2008-03
4 Wo Xingde,Yu Ying Zhe jiang University of TCM,Homg Zhou (310053);Research on Inhibition of Cell Apoptosis and Multidrug Resistance (MDR)[J];Journal of Zhejiang University of Traditional Chinese Medicine;2006-05
5 LIN Zhi-bin△, WANG Peng-yun(Department of Pharmacology, Peking University School of Basic Medical Sciences, Beijing 100083, China);The pharmacological study of Ganoderma spores and their active components[J];Journal of Peking University(Health Sciences);2006-05
6 HUANG Xiao-Jun1, YANG Jia-Ji1, WANG Chun-Mei1, HUANG Xiao-Feng1, LI Zhen1, CAO Yun-Xin2, YU Hua1, WANG Shuang1, CHEN Dan1 1Electron Microscopic Center, 2Department of Immunology, Fourth Military Medical University, Xi'an 710033, China;Growth and apoptosis of Hep G-2 cells affected by extremely low-frequency electromagnetic field[J];Journal of The Fourth Military Medical University;2005-24
7 Han Zemin, Li Delun, Xue Zhenxun Department of Oro maxillofacial Surgery, Qindu Stomatology Hospital, Fourth Military Medical University, Xi'an 710033;The study of effects of static magnetic field induced and combined with Pingyangmycin chemotherapy on human lingual cancer cell[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;1997-02
8 LI Zu-Qiang~(1*),MA Guo-Yi~(2),LUO Lei~(3),ZHANG Xi-Tai~(2)(1.Experimental Center,College of Chemistry and Material Engineering,Yunnan University,Kunming 650091,China;2.Faculty of Pharmacy,the University of Sydney,NSW,Australia;3.Chemical & Engineering College,Yunnan Normal University,Kunming 650092,China);Sesquiterpene Lactones from Cyathocline purpurea[J];Chemical Journal of Chinese Universities;2006-05
9 ZOU Xiang-yang~1,LI Lian-hong~2.(~1Department of Biology,Dalian Medical University,Dalian 116027;~2Department of Pathology,Dalian Medical University,Dalian 116027,P.R.China)Correspording anthor: ZOU Xiang-yang.E-mail: zouxiangyang@126.com;Cell Cycle Control and Tumor[J];International Journal of Genetics;2006-01
10 XIAO Chu-yao,DING Yue,JIANG Jian-min(School of Pharmaceutical Sciences,Sun Yat-sen University,Guangzhou 510080,China);Novel anticancer agents:PI-88 and its mimetics[J];Journal of International Pharmaceutical Research;2008-06
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 YU ZHU-QIN,LIU ZONG-BAO,GONG SHAO-LAN,et al(Department of Medicine,Songshan Hospital,Qingdao University Medical College,Qingdao 266021,China);EFFECTS OF LAMINARIA JAPONICA ON SERUM LIPID IN RATS WITH EXPERIMENTAL HYPERLIPEMIA[J];Acta Academiae Medicinae Qingdao Universitatis;2010-05
2 LI Lin1,QIU Rong-li2,ZHOU Chang-hui2,SHI Ying-ying2,HAN Ying2,LU Yin1(1Institute of Chinese Medicine,Nanjing University of Chinese Medicine,Nanjing,Jiangsu,210046,China;2Pharmacology College of Nanjing University of Chinese Medicine,Nanjing,Jiangsu,210046,China);Effect of Polysaccharides from Fructus Ligustri Lucidi on Immunity of Tumor-bearing Mice[J];Journal of Nanjing University of Traditional Chinese Medicine;2008-06
3 JI Yu-bin1,2,GAO Shi-yong1,2,JI Chen-feng1,2,ZOU Xiang1,2(1.Postdoctoral Programme,Institute of Materia Medica,Center of Research and Development on Life Sciences andEnviroment Sciences of Harbin University of Commerce;2.Engineering Research Center ofNatural Anticancer Drugs,Ministry of Education.Harbin 150076,China);Effects of solanine on kinetic constants of NATase in HepG_2 cells[J];Chinese Pharmacological Bulletin;2008-09
4 ZHANG Rui,XU Hua-li,YU Xiao-feng,QU Shao-chun,CHEN Ming-xia,SUI Da-yuan(Dept of Pharmacology,School of Pharmacy,Jilin University,Changchun 130021,China);Effect of 20(S)-Protopanaxadiol on SMMC-7721 human liver cancer in vivo and in vitro[J];Chinese Pharmacological Bulletin;2008-11
5 LI Lin,QIU Rong-li,CHENG Ge,SHI Ying-ying,HAN Ying,GAO Yu,LU Yin(Nanjing University of Traditional Chinese Medicine,Nanjing 210029,China);The study on the anti-tumor effect of LLP in vitro and in vivo[J];Chinese Pharmacological Bulletin;2008-12
6 TAN Hui-xin(Pharmacy Department of the Forth Affiliated Hospital to Harbin Medical University,Harbin 150001,China);Research progress on topoisomerase Ⅰ inhibitors[J];Chinese Pharmacological Bulletin;2009-04
7 YANG Yi-dong1,CHEN Ye-gao2,WU Hui1,FANG Tian-tian1,ZHANG Yan-li1,QING Chen1(1.Yunnan Key Laboratory of Pharmacology for Natural Products Research,Kunming Medical College,Kunming 650031,China;2.Faculty of Chemistry and Chemical Engineering,Yunnan Normal University,Kunming 650092,China);Antitumor activity of compound Mirabijalone B and its effect on DNA topoisomerases[J];Chinese Pharmacological Bulletin;2009-10
8 LI Yan-mei1,2,SHEN Xiao-yan1 (1. Laboratory of Pharmacology and Toxicology,School of Pharmaceutical Sciences, Sun Yat-Sen University,Guangzhou 510275,China;2. Bio-Pharmacy Technology of R & D Center,Institutes of Life & Health Engineering,Jinan University,Guangzhou 510632,China);Progress in the study of G-quadruplex telomerase inhibitors[J];Chinese Pharmacological Bulletin;2010-01
9 GAO Shi-yong1,2,LANG Lang1,2,ZOU Xiang1,2,JI Chen-feng1,2,JI Yu-bin1,2,MA Qiang1,2,YUE Lei1,2,QU Zhong-yuan1,2,SHANG Ming1,2(1.Post-doctoral Research Station,Institute of Materia Medica,Center of Research and Development on Life Sciences and Environment Sciences of Harbin University of Commerce,Harbin 150076,China;2.MOE Engineering Research Center of Natural Anticancer Drugs,Harbin University of Commerce,Harbin 150076,China);Inhibition of humulon on arylamine N-acetyltransferase-1 activity and gene expression in SGC-7901 cells[J];Chinese Traditional and Herbal Drugs;2010-05
10 OU Xian-hong1,2,LIU Hua-gang1,XU Heng3(1.Dept of Pharmacology,3.Medical Experimental Center,Guangxi Medical University,Nanning 530021,China;2.Dept of Pharmaceutics,Guilin Medical University,Guilin Guangxi 541004,China);The new progress in research of antitumor targets for natural alkaloids and their derivatives[J];Chinese Pharmacological Bulletin;2010-06
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 JIANG Chao, QING Chen, MENG Ling hua, et al. Shanghai Institute of Material Medical,Chinese Academy of Sciences,Shanghai 200031,P.R.China;Inhibitory effects of China ganoderma lucid essence (CGLE) on DNA topoisomerases and its ability to induce apoptosis of K562 cells[J];CHINESE JOURNAL OF CANCER;1999-06
2 QING Chen, JI Shu-yu, WANG Lei (Yunnan Key Laboratory of Pharmacology for Natural Products Research, Kunming Medical College, Kunming 650031 );Effects of Qingshan Antitumor Injection on Tumor Growth in Mice[J];Academic Journal of Kunming Medical College;2003-02
3 TANG Tao, MENG Ling Hua, CHEN Ling Ji, DING Jian (Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031);Reversal of multidrug resistance and inhibition of DNA topoisomerase Ⅱ by emulsion of seed oil of Brucea Javanica[J];Chinese Pharmacological Bulletin;2001-05
4 LU Yin 1, 2 ,SUN Zhi Guang 3, CHEN Wen Xing 2, WANG Ai Yun 2,LI Ling 2,ZHU Quan 2 ( 1Model Animal Research Centre, Nanjing University, Nanjing 210000) 2Nanjing University of TCM,Nanjing 210029 3Hospital of TCM of Jiangsu Province, Nanjing\ 210029;Effect of procyanidins on carcinogen-induced DNA damage and topoisomerase[J];Chinese Pharmacological Bulletin;2003-01
5 ZHOU Jian-Jun~*, YUE Xiu-Fang, HAN Jia-Xian, YANG Wei-Yi (Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031);IMPROVED MTT ASSAY FOR ACTIVITY OF ANTITUMOR AGENTS[J];Chinese Journal of Pharmaceuticals;1993-10
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved