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《Chinese Pharmacological Bulletin》 2009-12
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Research progress in molecular mechanism of the pharmacological actions of emodin

LIU Han,GAO Yun(Dept of Physiology,Basic Medical College of Nanchang University,Nanchang 330006,China)  
Emodin is the main effective monomer of Rhubarb,which has a variety of pharmacological actions and valuable clinical applications.Recently,there are many reports about molecular mechanisms of emodin pharmacological actions,and they givehighly attention on the dephlogisticating and antineoplastic effects.These effects are achieved through affecting the concentration and transportation of ions,resisting of oxidation and free radical,and affecting the secretion of inflammatory factor and the enzyme activity and apoptosis and so on.This article summarizes the reports and hopes to provide theoretical basis for the practical application.
【Fund】: 国家自然科学基金资助项目(No30860333);; 江西省自然科学基金资助项目(No2007GZY1002)
【CateGory Index】: R285
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