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《CHINESE PHARMACOLOGICAL BULLETIN》 1995-01
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Antimutagenic effects of Gypenosides(GP)in salmonella test

WANG Ying-Jin;BAI Yuan-Rang (Dept of Pharmacology, Xi'an Medical University, Xi'an 710061)  
Aset of histidine-requiring strains TA97.TA98.TA100,TA102was used for antimutagenicity test.4 mutagenic agents such as Atabrine(AB).Daunorubicin (DN).Sodium Axide(SA).Mitomycin C(MMC) were used to make mutagenic model and antimutagenic effects of GP was observed,Every tester strain was divided intocontrol group·model group and GPgroups.AB.DN.SA and MMC were mutagenic agents for TA97,TA98,TA100and TA102respectively.The results showed that GPinhibited mutagenic effects induced by 4 model agents. The inhibitory rates were56.0% ,74.7% .94.5% for AB; 23.1% , 40.2% , 57.9% for DN; 34.0% , 59.3%, 94.5% for SA and 22.0% . 50. 5% . 64. 3% for MMC respectivelThese data suggestthat GP has the effects of inhibiting mutagenesis induced by AB.DN, SA, MMC insalmonella test with dose-dependent manner and is very likely to have a protective action on the carcinogens.
【CateGory Index】: R96
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【References】
Chinese Journal Full-text Database 1 Hits
1 Guo Suzhi Zhang Guojun Zhang Yusong Yang Jiangfan (Fujian Agriculture and Forestry University, Fuzhou 350002);Studies on the Extraction Conditions of Health Components in Gynostemma Pentaphyllam[J];Journal of Chinese Institute of Food Science and Technology;2005-04
【Citations】
Chinese Journal Full-text Database 3 Hits
1 Znou Zongcan, et al. ( Beijirig Medical University );Screening Study on the Antimatagenicity of 57 Crude Drugs In vitro[J];Journal of Health Toxicology;1989-04
2 QIAN Bo-chu, ZANG Xing-xing, CHEN Jue, XU Heng-jun, LIU Xue-li, YUAN Yu-ying, PENG Xiao-ying(Department of Pharmacology, Institute of Materia Medica, Zhejiang Academy of Medicine, Hangzhou 310007);Influence of gypenosides on immunological function in rodents[J];Chinese Journal of Pharmacology and Toxicology;1986-01
3 Liu Dexiang, Yin Xuejun, Wang Hechuan, Zhou Yu Zhang Yuhong (Laboratory of Medical Genetics, Western Region Hospital, Urumqi 830000);Antimutagenicity Screening of Water Extracts from 102 Kinds of Chinese Medicinal Herbs[J];China Journal of Chinese Materia Medica;1990-10
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 SUN Zhi guang\+1, ZHAO Wan zhou\+2, LU Yin\+2, TANG Ling fang\+3, ZHANG Zhen ling\+3, ZHANG Shi wei\+2 (1. Department of Digestion, Hospital of TCM of Jiangsu Province, Nanjing 210029; 2. College of Traditional Chinese Herbs, Nanjing University of T;ANTIMUTAGENIC EFFECT OF PROCYANIDINS FROM VITIS VINIFERA SEED IN SALMONELLA TEST[J];Carcinogenesis,Teratogenesis and Mutagenesis;2002-03
2 WANG Li, XING Sui guang, AN Chang xin (Department of Histoiogy and Embryology, Xinjiang Medical University, Urumqi 830054, China);EFFECT OF CHLOROFORM EXTRACTS FROM ISATIS INDIGOTICA LEAVES ON MALE GERM CELLS IN MICE[J];Carcinogenesis,Teratogenesis and Mutagenesis;2002-04
3 WANG Ju-xiang, PEI Shi-geng, MEN Jin-e, et al(Derparment of Hygien , Hebei Engineering College,Handan 056029,China;Derparment of oto Laryngology,the Affiliated Hospital of Hebei Engineering College, Handan 056000,China;Experimental Center of the Medical Faculty, Hebei Engineering College, Handan 056000, China);Antagonistic Effect of Propolis on Mutation Induced by Thiolepa, Adriacin and Acridine Orange[J];Carcinogenesis,Teratogenesis and Mutagenesis;2005-01
4 Suzhen,Wang Jiaji, Wei Lingzhen,Sun Meifang, WangQuna,Zhang Youran.Dept.of TOxicology,Anhui Mtdical University, Hefei 230032;THE ANTIMUTAGENIC EFFECT OF 7 CHINESE HERBALMEDICINEshe[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1994-02
5 Lu Yao ,Pang Huimin ,Wu Guangheng ,Zhang MengqiuNorman Bethune University of Medical Sciences,School of Basic Medicine Changchun130021 the Third Teaching Hospital;REPARABLE ACTION AND TIME EFFECTS OF GINSENOSIDES ON GENETIC DEMAGE[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1994-03
6 WEN De-zhong, ZHANG He-yan, ZHU Yu-zhuo , ZHANG Li-jiao ( Department of Medical Genetics, School of Basic Medical Sciences, Jilin University, Changchun 130021, China; Department of Chinese Traditional Medicine, China-Japan Union Hospital, Jilin University, Changchun 130033, China; Department of Cell Biology, School of Basic Medical Sciences, Jilin University, Changchun 130021, China );Protective effect of Poly gala tenui folia willd on genetic damage and enhancement of lymphocyte function induced by cyclophosphamide in mice[J];Journal of Jilin University(Medicine Edition);2006-01
7 Wang Honglin;Chen Xiaodong;Luo Suilan et al(Department of Toxicofogy,Baotou Medical COllege,Baotou 014010);Studies of the Antimutagenesis of Lycium Chinese Mill Tea and Other Related Prlducts[J];JOURNAL OF BAOTOU MEDICAL COLLEGE;1995-02
8 Wan Jijin Ge Zhenhua et,al (Dept.of Modern Medicine,FCTCM;Fujian Institute of TCM & Pharmacology);The Effects of Gynostenmma Pentaphyllum on Proliferation & Immunity of Tumor Cells[J];Journal of Fujian College of Traditional Chinese Medicine;1993-03
9 Pang Zhilin 1, Tang Jun 2 ,Zhu Weryun 1, Lu Yao 3 ( 1Department of Medical Genetics & Cell Biology,Guangzhou Medical College; 2Department of Microbiology & Immunology,Guangzhou Medical College; 3School of Basic Medical Sciences,N;Genetic Toxicity of Water Boiled Juice of Isatic Tinctoria L. in Mice[J];ACADEMIC JOURNAL OF GUANGZHOU MEDICAL COLLEGE;2000-03
10 XU Hou quan,GUO Dong mei,HAN Fa bin,et al Department of Environmental Health,Shandong Medical University,Jinan 250012;Study on Antagonism of Natural Plants Extracts on Chromosomal Damages Induced by Chromium(Ⅵ)[J];JOURNAL OF ENVIRONMENT AND HEALTH;2000-02
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Lin Xin, Li Ge, Li Wenkui, Cai Youyu, Xiao Peigen Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing 100094 Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences, Beijing 100021;IN SITU NICK TRANSLATION METHOD REVEALS THE ANTIMUTAGENIC EFFECT OF THE TOTAL SAPONINS OF CIMICIFUGA DAHURICA[J];Carcinogenesis,Teratogenesis and Mutagenesis;1993-04
2 Wang Tingxin, Qin Shuzheng, Zhao wen, Jiang Dongsheng, Ma Xiaotong, Bian Qiangrong HeBei Sanitary Epidemic Station, Baoding\ 071000;INHIBITORY EFFECT OF LAMINARIA JAPONICA POLYSACCHARIDES ON MICRONUCLEUS RATE INDUCED BY CYCLOPHOSPHAMIDE IN MICE[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1999-02
3 YANG Sheng-li, HAN Shao-yin, ZHANG Qiao, DING Lan-ping, SONG Ai-yun, GONG Ya-ou, ZHANG Tan-mu (Department of Esophageal Cancer Research, Henan Medical University, Zhengzhou 450052, China);STUDY ON THE ANTIMUTAGENICTTY OF ORIDONIN[J];Carcinogenesis,Teratogenesis and Mutagenesis;2001-01
4 XIANG Hua\+1,ZHAO Jian-zhong\+2, BO Lin\+2 (1.Hygiene and Anti-epidemic Station of Hangzhou, Hangzhou\ 310006, China; 2.Department of Cytobiology, College of Biological Sciences, Zhejiang University, Hangzhou 310009, China);STUDY ON THE ANTIMUTAGENICITY OF SEAWEED POLYSACCHARIDES[J];Carcinogenesis,Teratogenesis and Mutagenesis;2001-01
5 GUO Wei, ZHAO Ze-zhen, SHAN Bao-en, WEI Li-zhen, WEN Deng-gui(Hebei Cancer Institute, The 4+{th} Hospital of Hebei Medical University, Shijiazhuang 050011, China);REPORT ON THE ANTIMUTAGENICITY AND ANTI-TUMOR ACTIVITY OF SIX KINDS OF CHINESE MEDICINAL HERBS[J];Carcinogenesis,Teratogenesis and Mutagenesis;2002-02
6 ZHANG Chun_ling, HU Jun_feng, QU Jiang_bin, et al.(School of Public Health, Shandong University, Jinan 250012 , Ch ina);STUDY ON ANTIMUTAGENICITY OF CHINESE HERBAL MEDICINE AND GREEN TEA TO BENZOAPYRENE AND NNK[J];Carcinogenesis,Teratogenesis and Mutagenesis;2003-02
7 ZHANG Quan-xin, NIE Mu-hai (Department of Toxicology, Guangzhou Center for Diseases Prevention and control, Guangzhou 510080, China);Anti-mutagenicity test of PS8812 Polysaccharides and its Selenium Polysaccharides[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-01
8 Du Yangyang and Mo ZiyaoGuangzhou Anti-epidemic Station,Guangzhou 5l0080;STUDY ON THE MUTAGENIC AND ANTIMUTAGENIC POTEN-TIALS OF GYPENOSIDES(GPS)IN MICE[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1995-03
9 Gao Minxin, Sui Zijie, Yang Hongqun, Wang Wei, Zhao Shengyou Health and Anti epidemic Station of JiLin province, ChangChun\ 130021;THE EFFECTS OF GINSENG ROOT SAPONINS ON ANTI DNA DAMAGING AND ANTI MUTATIONS[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1998-02
10 SI Wei ke*, GAO Li hong, LIU Bing, CHENG An, LI Peng, YAO JieDepartment of Clinical Biochemistry, the Third Military Medical University, Chongqing 400038, P.R.China;Regulation of G_1 Phase Cell Cycle Regulation Factors in Differentiation and Apoptosis of Matrine Induced Hepatoma Cells[J];Chinese Journal of Cancer;2001-08
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 HOU Hui-li,FU Tong-sheng(College of Animal Medicine,Hunan Agricultural University,Changsha,Hunan,410128,China);Research Advance in the Chemical Ingredients and Pharmacological Effects of Gynostemma pentaphyllum[J];Progress in Veterinary Medicine;2006-S1
2 ZHANG Yu-song1,YANG Jiang-fan2,XIAO Gui-ping3,ZHANG Jing-xian4(1.Tea Processing Factory;2.College of Horticulture;3.College of Food Science,Fujian Agriculture and Forestry University,Fuzhou,Fujian 350002,China;4.Quanzhou Agricultural Bureau,Quanzhou,Fujian 362000,China);Extraction conditions for ginsenoside,flavone,polysaccharide in dry and fresh Gynastemma pentaphyllum and processing technique of the beverage[J];Journal of Fujian Agriculture and Forestry University(Natural Science Edition);2007-05
3 Rui Wen, Cen Yyingzhou, Xing Yingying, Su Miaoxian(Jinan university, Guangzhou 510632,China);Research on the Antihepatitis Herbal Medicine of Yao Nationality[J];Guangdong Chemical Industry;2005-03
4 HUI Rui-hua, HOU Dong-yan, LI Tie-chun, LIU Xiao-yuan Department of Chemistry, Anshan Normal University, Anshan 114005, China;Simultaneous Determination of Total Flavone and Total Saponin in Gynostemma Pentaphyllum by Signal Multiplier Spectrophotometry[J];Spectroscopy and Spectral Analysis;2006-09
5 YANG Jiang-fan~1, ZHANG Yu-song~2(1. College of Horticulture, Fujian Agriculture and Forestry University;2.Tea Factory, Fujian Agriculture and Forestry (University), Fuzhou, Fujian 350002, China);Preparation technique of Gynostemma pentaphyllam chewable tablet[J];Sugarcane;2005-01
6 ZHANG Yu-song(Science and Technology Developing Corporation,Fujian Agriculture and Forestry University,Fuzhou,Fujian 350002,China);Study on microwave-assisted extraction of gypenosides from leaves of Gynostemma pentaphyllum[J];Subtropical Agriculture Research;2008-03
7 LI Ya-jing et al (Zhejiang Economic and Trade Polytechnic,Hangzhou,Zhejiang 310018);Effect of Complex Liquid of Gynostemma pentaphllum on Fatigue Resistance of Mice[J];Journal of Anhui Agricultural Sciences;2009-29
8 ZHENG Xiao-jiang (Hubei Institute for Nationalities, Enshi 445000,China);Composition Analysis of "Enqiyetian", "Enwayemi" and Proto-variety of Gynistemma Penaphyllum Makino[J];Journal of Hubei Institute For Nationalities;2002-03
9 TANG Ting~1,YUAN Hui-ning~2,MA Jian-ping~3(1.Dept.of Pharmaceutical Analysis,Medicine and Health Management College;2.Function Laboratory,Dept.of Basic Medicine;3.Clinical Medical Colleg,Hangzhou Teachers College,Hangzhou,Zhejiang 310036,China);The preliminary study on extraction technology of gynosaponins[J];Journal of Hangzhou Teachers College(Medical Edition);2006-01
10 ZHANG Tao1,ZHANG Yu-song2,YUAN Di-shun1,2 (1.Agricultural Product Quality Institute,FAFU,Fuzhou 350002,China;2.Institute of White Tea,Fujian Agriculture & Forestry University,Fuzhou 350002,China);Studies on Microwave-assisted Water Extraction of Health Components in Gynostemma pentaphyllum[J];Acta Agriculturae Universitatis Jiangxiensis;2008-05
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 Yin Xuejun;Analysis of MN and CA in Mouse Spleen and Bone Marrow Cells[J];Hereditas(Beijing);1988-06
2 Xu XueYing, Li Yuan and Xu Jin(Department of Antibiotic, Institute of materia Medica, Chinese Academy of medical Sciences, Beijing);A MODIFIED HUMORAL IMMUNE ASSAY METHOD A METHOD OF HEMOLYSIN DETERMINATION.[J];Acta Pharmaceutica Sinica;1979-07
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