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《CHINESE PHARMACOLOGICAL BULLETIN》 1996-06
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Effects of berberine sulphate on immune system

GENG Dong Sheng, LIU Fa, LIU Xue Bin, YANG Yong Xin (Department of Pharmacology, Xinjiang Medical College, Urumqi 830054)  
In previous studies, it found that berberine had the effects of antibacteria, anti inflamation and restraining the growth of tumor cells. These should have been closely connected with immunity effects. Therefore, we had studied the effects of berberine sulphate (BS) on immune system of mice in vitro and vivo . The results showed that BS with 10 -4 and 10 -5 mol. L -1 increased phagocytosing function of peritoneal macrophages (PMΦ) in mice and peripheral leukocytes in human, the production of IL 1 by PMΦ in mice, inhibited the production of IL 2 produced by spleen cells, the lymphocyte transformatiom of both T and B. With 25,50 mg·kg -1 , BS accelerated the clearance rate of charcoal particles, decreased the development of serum hemolysin concentration 50% and the delayed type hypersensitivity reaction. It was suggested that BS increase non specific and decrease specific immunity in mice.
【CateGory Index】: R967
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【References】
Chinese Journal Full-text Database 10 Hits
1 ZHOU Xia;PENG Yao-zong;HUANG Tao;LI Ling;MOU Shao-xia;KOU Shu-ming;LI Xue-gang;College of Pharmaceutical Science,Southwest University;School of Life Science,Southwest University;Engineer Research Center of Chongqing Pharmaceutical Process and Quality Control;;Effects of alkaloids from Coptidis Rhizoma on mouse peritoneal macrophages in vitro[J];中国中药杂志;2015-23
2 ZUO Yan;LIU Guoliang;ZHONG Xiaobo;HUANG Xiaoqing;Department of Endodontics,the Affiliated Hospital of Stomatology,Chongqing Medical University;Chongqing Research Center for Oral Diseases and Biomedical Science;Department of Periodontology,the Affiliated Hospital of Stomatology,Chongqing Medical University;;Study of the chitosan thermosensitive hydrogel loading Drynaria Rhizome, Coptis chinensis and Panax notoginseng in experimental regeneration of periodontal defect[J];重庆医科大学学报;2013-09
3 LIU Xin-min(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China);Clinic experience of the treatment on immunological infertility by professor LI Guang-rong[J];中华中医药杂志;2012-05
4 HUANG Gui-ping. Department of Internal Medicine,Dajishan Region Hospital,Jiangxi 341801,China;Effect observation of berberine and sucralfate in the treatment of chronic gastritis[J];中国实用医药;2009-12
5 XU Xiao-wei and ZHANG De-xian Department of Endocrinology and Diabetes Mellitus,Qingdao Hiser Medical Center,Shandong(266033);Effect of Tangyikang in Improving the Function of Pancreatic Islet β Cells in Patients with Latent Autoimmune Diabetes Mellitus in Adults[J];中国中西医结合杂志;2008-10
6 SUN Gui-bo1,3,DENG Xiang-chao2,GUO Bao-jiang3,LI Xu-e3,XU Hui-bo4,SUN Xiao-bo1(1 Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100094,China;2 Guangzhou University of Chinese Medicine,Guangzhou 510405,China;3 College of Life Science,South China Normal University,Guangzhou 510631,China;4 Academy of Traditional Chinese Medicines and Medica of Jilin Province,Changchun 130021,China);Study on anti-tumor effects of anthraquinone glycosides from Polygonum multiflorum[J];中国新药杂志;2008-10
7 YANG Yong1 DING Xiao-gang2 (1.The southwest university, Chongqing 400716;2.Shenzhen Huatai Animal Medicine Co., Ltd, Guangdong, Shenzhen, 518112);Ten Pharmacological effects of Berberine[J];科技信息(科学教研);2008-05
8 CHEN Han-ying1,LIU Li-mei2,XU Jian-qin1,LIU Feng-hua3(1.College of Veterinary Medicine,China Agricultural University,Beijing 100094,China;2.Research Institute of the Chinese Medicine Rationale,China Academy of the Traditional Chinese Medicine,Beijing 100700,China;3.Beijing Agricultural College,Beijing 102206,China);Effects of four Cortex phellodendri alkaloids on proliferation and levels of IFN-γ and IL-4 in mouse splenic lymphocytes after heat stress[J];中国兽医科学;2007-07
9 NIU Xiao-Hui,JI Feng-Lan, ZHANG Wei,XU Hui-Bo,SUN Xiao-Bo, LI Yu. Academy of Traditional Chinese Medicine and Material of Jilin Province, Changchun 130021, China;Influence of CVPS on IL-1,IL-2,IFN-γ and TNF[J];中国免疫学杂志;2006-12
10 HUANG Zhi-jian,LU Li-ming(College of Animal Science,Fujian Agriculture and Forestry University,Fuzhou 350002,China);Pharmacokinetics of Compound HuangBo Granule in Mice[J];畜牧兽医学报;2006-01
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Chu Zhonglu,et al (Department of Biochemistry);EFFECTS OF BERBERINE ON PLATELET AGGREGATION AND RELEASE[J];第二军医大学学报;1989-04
2 CHEN Qi-Ming and XIE Ming-Zhi (Institute of Materia Medica, Chinese Academy of Medieval Sciences, Beijing);EFFECTS OF BERBERINE ON BLOOD GLUCOSE REGULATION OF NORMAL MICE[J];药学学报;1987-03
【Co-citations】
Chinese Journal Full-text Database 7 Hits
1 YUAN Zhi-yi;WANG Yu-gang;CHAI Yu-shuang;HU Jun;JIANG Jing-fei;YAN Xiao-jin;DU Li-jun;Laboratory of Molecular Pharmacology and Pharmaceutical Sciences,School of Life Sciences,Tsinghua University;;Berberine action targets and its absorption behavior:how to use old drug for new mechanisms[J];中国中药杂志;2016-12
2 QU Hua;ZHANG Ying;MAO Hui-min;GAO Zhu-ye;SHI Da-zhuo;Beijing University of Traditional Chinese medicine;Xiyuan Hospital Affiliated to China Academy of Chinese Medical Science;;Research Progress of Coptis and Its Extracts in Treating Cardiovascular Disease[J];中医药导报;2016-06
3 Zhan Hongjing;Chen Haoyun;Lin Caixia;Zhang Chengfang;Kuang Shan;Zeng Zhihong;Zhu Yanghuan;Dong Guan City eastern part of the city hospital;;Effects of berberine on T2DM and high lipid serum NO level in patients with hyperlipidemia and the activity of SOD[J];北方药学;2015-04
4 CHEN Lu;ZHANG Hong;Traditional Chinese Medicine and Western Medicine Drum Tower,Clinical Medical College of Nanjing University of Chinese Medicine;Gulou Hosipital of Nanjing University;;Mechaniam of Berberine on Treating 2-DM[J];辽宁中医药大学学报;2013-11
5 JIA Yan-Jun,and LI Jian-Jun(Chinese Academy of Medical Science & Peking Union Medical College & National Center for Cardiovascular Diseases & Fuwai Hospital & State Key Laboratory of Cardiovascular Disease,Beijing 100037,China);The Effect of Anti-atherosclerosis of Berberine and Its Mechanism[J];中国动脉硬化杂志;2013-04
6 DING Yang-ping1,4,YE Xiao-li2,ZHOU Jie1,LOU Qiao-ming3,LIAN Meng-fei1,LUO Sai1,LI Xue-gang4 1.School of Food Science,Southwest University,Chongqing 400716,China 2.School of Life Science,Southwest University,Chongqing 400716,China 3.School of Marine Science,Ningbo University,Ningbo 315211,China 4.School of Pharmaceutical Science,Southwest University,Chongqing 400716,China;Research progress in hypoglycemic mechanism of berberine[J];中草药;2013-06
7 Tang Si,Zhang Yan,Tu Xiang,Xie Chunguang Chengdu University of Traditional Chinese Medicine,Chengdu,Sichuan,China 610075;Research Review on the Mechanism of Berberine in Reducing Blood Sugar of Type 2 Diabetes[J];中医学报;2012-07
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 WANG Jian,LIU Zong-xia,WANG Peng,LIU Rui-gang,LI Shu(Weifang Stomatological Hospital,Weifang 261011,China);Expression of matrix extracellular phosphoglycoprotein in periodontal wound healing[J];牙体牙髓牙周病学杂志;2011-05
2 YE Sha-sha,ZENG Yao-ying,YIN Le-le Institute of Tissue Transplantation and Immunology,College of Life Science and Technology,Jinan University,Guangzhou 510632,China;Effects of salidroside on proliferation,apoptosis,phagocytosis,ROS and NO production of murine peritoneal macrophages in vitro[J];细胞与分子免疫学杂志;2011-03
3 LI Xiao-fang,FENG Xiao-qiang,YANG Sheng(College of Life Science and Chemistry,Tianshui Normal University,Tianshui 741001,China);Synthesis,antimicrobial activity and effect of O-carboxymethyl chitosan on cell membrane protein[J];食品工业科技;2010-04
4 HU Qi-yong1,CHEN Li-li1,WANG Ren-fei2(1.Department of Stomatology,The Second Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou 310009,China;2.Hangzhou Stomatology Hospital,Hangzhou 310006,China);Traditional Chinese medicine Drynaria fortunei J. Smith naringin promotes proliferation and differentiation of human periodontal ligament cells[J];浙江大学学报(医学版);2010-01
5 JIANG Jun-qiang1, DING Yi2, LI Xiao-yu3, CAI Wei1, WANG Zhong-chao1. (1. Dept. of Oral Medicine, Stomatological Hospital of Luzhou Medical College, Luzhou 646000, China; 2. Dept. of Periodontology, West China College of Stomatology, Sichuan University, Chengdu 610041, China; 3. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China);Effects of Drynaria fortunei naringin on proliferation, alkaline phosphatase activity of human periodontal ligament cells[J];华西口腔医学杂志;2009-05
6 JI Qiu-xia,DENG Jing,YU Xin-bo,XU Quan-chen,XU Xiao-yan.(Department of Stomatology,The Affiliated Hospital of Qingdao University Medical College.Qingdao 266003,Shandong Province,China);An in vitro evaluation of the antibacterial activity of chitosan-based thermosensitive hydrogel against periodontal pathogens[J];上海口腔医学;2009-04
7 DU Wei-feng,WANG Ming-yan,CAI Bao-chang(Jiangsu key Laboratory of Chinese Medicine Processing,Nanjing University of Chinese Medicine,Nangjing 210029,China);Effect of Polysaccharides in Crude and Processed Cornus officinalis on the Immunologic Function of Mice with Immunosuppression Induced[J];中药材;2008-05
8 MA Zhi-wei1, ZHANG Yong-jie2, WU Zhi-fen1, WANG Rong3, ZHU Hao1, LI Yuan2, XU Jie1, LIU Qing1. (1. Dept. of Periodontology and Mucosal Diseases, College of Stomatology,The Fourth Military Medical University, Xi'an 710032, China; 2. Central Laboratory for Tissue Engineering, College of Stomatology, The Fourth Military Medical University, Xi'an 710032, China; 3. Dept. of Pharmacology, College of Stomatology,The Fourth Military Medical University, Xi'an 710032, China);A study on the effect of the chitosan thermosensitive hydrogel loading recombinant human bone mor-phogenetic protein-2 on repairing periodontal defects[J];华西口腔医学杂志;2008-01
9 GE Lin-hu,YE Xiao-li,ZHOU Shao-boSchool of Life Science,Southwest University,Chongqing 400715,Chin;Effect of Houttuyfonate Homologues on the Fluorescence Characteristics of Membrane Proteins of Macrophage[J];西南大学学报(自然科学版);2007-08
10 LU Jin-song,LIU Yu-qing,LI Ming,LI Bao-sheng,XU Yan(Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine,Beijing 100700,China);Protective effects and its mechanisms of total alkaloids from rhizoma Coptis chinensis on Helicobacter pylori LPS induced gastric lesion in rats[J];中国中药杂志;2007-13
【Secondary References】
Chinese Journal Full-text Database 7 Hits
1 YANG Zhaobin;CHEN Wenwen;CHEN Quan;HUANG Lingling;HUANG Daofeng;QIU Luzhen;Medical Intensive Care Unit, Zhangzhou Affiliated Hospital of Fujian Medical University;Department of Neonatology, Zhangzhou Affiliated Hospital of Fujian Medical University;Department of Neurosurgery, Fujian Medical University Union Hospital;;Dynamic changes of immune function in mouse peritoneal macrophages induced by LPS[J];免疫学杂志;2018-01
2 Xiong Feisheng;Chai Jie;Li Minping;Zhu Qingqing;Zhan Guangsheng;Zhu Ying;;Clinical Observation on Sequelae of Pelvic Inflammatory Disease of Accumulation of Dampness Heat and Blood Stasis Type Treated by Combination of Acupuncture and Chinese Medicine[J];实用中医药杂志;2017-10
3 CHEN Kai;WANG Yue-Liang;WANG Jia-Qi;DING Chuan-Bo;SONG Ming-Ming;LIU Wen-Cong;ZHANG Yi-Nan;LI Hui;Jilin Agricultural University College of Traditional Chinese Medicine;;Comparison of anti-inflammatory activity of ethanol extract of coptis chinensis Franch.and Berberine hydrochloride in vitro[J];中国免疫学杂志;2017-05
4 LI Si-jin;HU Ning-zhu;LI Yan-han;Institute of Medical Biology,Chinese Academy of Medical Sciences and Peking Union Medical College;;Effects of compound adjuvant of aluminium hydroxide and coptisine on humoral immune response induced by hepatitis A vaccine in mice[J];中国公共卫生;2017-05
5 Tang Zhini;Luo Yunpeng;Ge Fei;Zhang Mao;Luo Xun;Jiangxi University of Traditional Chinese Medicine;Chongqing Medical University;Children 's Hospital of Chongqing Medical University;;Research Advance of Antitumor Mechanism of Fuzheng Guben Chinese Herbal[J];儿科药学杂志;2016-11
6 LI Shuai-feng;DING An-wei;ZHANG Li;LAN Cai-wu;HE Ding-xiang;Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine;Suzhou Hospital of Chinese Medicine;Guizhou Changhao Chinese Medicine Development Co., Ltd.;;Optimization of integration of field processing and processing crude drugs of Polygoni Multiflori Radix[J];中草药;2016-17
7 TAN Shaohua;CHEN Yihui;HUANG Guangtai;HAN Liang;Department of Pharmacy,The Second Affiliated Hospital of Guangzhou Medical University;Guangzhou Chest Hospital;Guangdong Pharmaceutical University;;Analysis of Radix Polygoni Multiflori and Radix Polygoni Multiflori Preparata by UPLC/Q-TOF MS[J];今日药学;2016-08
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Chu Zhonglu, et al (Department of Biochemistry);THE ANTIPLATELET AGGREGATION AND DEAGGREGATION EFFECTS OF AL~(3+)[J];第二军医大学学报;1987-06
2 CHEN Qi-Ming and XIE Ming-Zhi (Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing);STUDIES ON THE HYPOGLYCEMIC EFFECT OF COPTIS CHINENSIS AND BERBERINE[J];药学学报;1986-06
3 Chu Zhonglu, et al( Department of Biochemistry);THE CORRELATION BETWEEN PLATELET ACTIVITY AND EXTRACELLULAR CALCIUM CONCENTRATION[J];第二军医大学学报;1986-02
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