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《Journal of Medical Science Yanbian University》 2006-01
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Effects of the compound Polygonatum on anti-hypoxia capacity and anti-tiredness in mice

JIN Ying-zi~1,QU Xiang-zhi~2,ZHANG Hong-ying~3(1.Department of Experimental Animals,Medical Department of Yanbian University;2.Department of Pharmacology,Yanbian University College of Basic Medicine;3.Department of Functional Experimental Science,Yanbian University College of Basic Medicine:Yanji 133000,Jilin,China)  
OBJECTIVE To study the effects of the compound Polygonatum on anti-hypoxia capacity and(anti-tiredness) in mice. METHODS The mice were observed by ordinary pressure hypoxia,loaded swimming and rotational stick to measure the survival time and endurance time after being given 2,4 g/kg(compound)(Polygonatum.) RESULTS The survival time under the condition of ordinary(pressure) hypoxia and the loadling swimming of high dosage group of compound Polygonatum were prolonged,and the endurance time of(rotational) stick of low and high dosage groups of compound(Polygonatum) was prolonged,respectively. (CONCLUSION) The compound (Polygonatum) has anti-hypoxia cpacity and anti-tiredness effects in mice.
【CateGory Index】: R285.5
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