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《Acta Genetica Sinica》 1988-05
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Enhancement of Endonuclease Activity and Repair DNA Synthesis by Polysaccharide of Spirulina plaennsis

Pang Qishen Guo Baojiang Ruan Jihong(Zhongkai Agricultural and Technical College, Guangzhou)  
The effect of a water-soluble polysaccharide from bluegreen alga Spirulina platensis ca excision repair was monitored by endonuclease assay and measuring unscheduled DNA synthesis (UDS).The results showed that the presence of the polysaccharide enhanced significantly both UV damaged DNA incision activity and UDS in the root-tip cells of Vicia faba irradiated with gamma-rays.We have examined the process of excision of two separate assays.It was found that the polysaccharide increased the initial rate and postponed the saturation of both incision activity and repair DNA synthesis.The implications of these findings for the pos-sible mechanisms are discussed.
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