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《Hereditas(Beijing)》 2002-02
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Double Stranded RNA (RNA inteference RNAi) in Different Creatures

HAN Bei 1,WANG Xiu-min 1,GU Xue-fan 1,2 (1.Molecular Biology Laboratory of Xinhua Hospital Shanghai 200092,China; 2.Pediatric Institute for Research of Shanghai Shanghai 200092,China)  
Double-stranded RNA could degrade mRNA of target gene.It is a useful way for studying gene function.It is used widely in different creatures,such as Arabidopsis thaliana,Caenorhabditis elegans,Drosophila melanogaster,Zebrafish,Mouse.This review is mainly related to the application of dsRNA in recent years
【Fund】: 国家自然科学基金资助项目 ( 39870 778);; 上海市卫生系统百人计划项目 ( 98BR0 35 )资助
【CateGory Index】: Q789
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