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《CHINESE JOURANAL OF SPORTS MEDICINE》 1995-02
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The Effects of Exhaustive Swimming on the Free Radical Metabolism and serum CK,LDH Activity in Rats

Zhang Yunkun;et al(Nanjing Institute of Physical Education)  
Sixteen rats were randomly divided into 2 groups. The rats of the experimental group were killed immediately after exhaustive swimming following 12 day's swimming training.The malondialdehyde(MDA)and superoxide dismutase(SOD)in brain,liver and skeletal muscle,and creatine kinase(CK),lactate dehydrogenase(LDH)in skeletal muscle and serum were determined.The results showed that the MDA content of rats'skeletal muscle significantly elevated after exhaustive swimming(p0.05).Serum CK and LDH activity increased(p0.05),The MDA and SOD in brain didn't change.The MDA of liver had a trend of increasing.The results indicated that exhaustive exercise would lead to an increased free radical generation.The high level of lipid peroxidation increased the permeability of cell membrane in skeletal musele.The effects of exhaustive exercise on free radical metabolism were different in various organs.
【CateGory Index】: G804.2
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