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Effect of Exhaustive Exercise on Free Calcium and Phospholipase A2 Activity in Rat Myocardial Mitochondria

Zhang Jun,et al The Teacher's College of Yangzhou University  
The alterations of exhaustive swimming on the mitochondria lipid peroxidation level, free calcuim content and phospholipase A2 activity in rat heart were investigated. The results showed that after exhaustive swimming the lipid peroxidation level and phospholipase A2 activity were increased significantly, free calcuim content was decreased significantly. The above findings suggested that exhaustive exercise may cause a substantial attack of oxygen radicals on the myocardial mitochondria. This might be one of the important factors for the injury of myocardial mitochondria and exhaustive fatigue induced by exhaustive swimming.
【CateGory Index】: R87
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