Studies on pharmacodynamics of selenium yeast
Zhang Anping, Ni Feizhou, Sheng Yuxian et al
Some of the pharmacological characteristics of selenium yeast have been investigated using a number of normal or abnormal animal models. In the mouse, selenium yeast (30~60 mg ·kg-1 ·d-1×1×d, ig) up-regulated the cellular immune reaction inhibited by cy-clophosphamide. The dose (60~90 mg ·kg-1×d-1×d, ig) protected the liver damage or reduced the gastric hemorrhage induced by CC14 or by restraint-stress respectively. It was also found that selenium yeast (25~50mg .kg-1×d-1×d,ig) improved the myocardial ischemia produced by pituitrin in the rats. These results indicated that selenium yeast could possess versatile pharmacological actions.