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《Acta Universitis Medicinalis Nahui》 2002-03
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The effect of hair dye on micronucleus in bone marrow PCE of mice

Sun Meifang,She Suzhen, Wei Lingzhen ( Dept of Toxicology, Anhui Medical University, Hefei 230032)  
Objective To study the mutagenesis of three kinds of hair dye using mouse bone marrow PCE micronucleus test. Methods The mice were divided into negative and positive control and three treated groups.Three kinds of hair dye were given for 5 days in doses of 5 000 , 2 500 , 1 250 mg/kg, and micronuclei in bone marrow PCE were analyzed. Results The micronucleus rates did not increase compared with the negative control ( P 0.05). Conclusion The hair dye does not induce increases of micronucleus rates.
【Fund】: 安徽医科大学校青年科研基金资助 (编号 :5 2 2 0 93 )
【CateGory Index】: R99
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